Catalog No.
YHD88001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Leu292
Predicted molecular weight
34.83 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P30281
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CCND3, G1/S-specific cyclin-D3
Olig1/2 Drive Astrocytic Glioblastoma Proliferation Through Transcriptional Co-Regulation of Various Cyclins., PMID:40428395
Increased protein expression of interleukin-10 and its signalling molecules in colon cancer progression: potential prognostic and therapeutic targets., PMID:40299210
[Relapse-related candidate genes and their clinicopathological connections of diffuse large B cell lymphoma]., PMID:40159024
Small nucleolar RNAs promote the restoration of muscle differentiation defects in cells from myotonic dystrophy type 1., PMID:40156865
Exploring potential additive effects of 5-fluorouracil, thymoquinone, and coenzyme Q10 triple therapy on colon cancer cells in relation to glycolysis and redox status modulation., PMID:40059278
Establishment and characterization of a new mouse gastric carcinoma cell line, MCC., PMID:39800685
Downregulated CCND3 Is a Key Event Driving Lung Adenocarcinoma Metastasis during Acquired Cisplatin Resistance., PMID:39781469
Cyclin D1-negative mantle cell lymphoma., PMID:39571691
Cone-rod homeobox transcriptionally activates TCF7 to promote the proliferation of retinal pigment epithelial and retinoblastoma cells in vitro., PMID:39559312
Upregulated let-7 expression in the follicular fluid of patients with endometriomas leads to dysfunction of granulosa cells through targeting of IGF1R., PMID:39521729
ZNF652 exerts a tumor suppressor role in lung cancer by transcriptionally downregulating cyclin D3., PMID:39500884
Impaired cyclin D3 protein degradation contributes to trastuzumab resistance in HER2 positive breast cancer., PMID:39487929
Structural requirements for the specific binding of CRABP2 to cyclin D3., PMID:39419021
Hepatoid thymic carcinoma in a polycythemia vera patient treated with ropeginterferon Alfa-2b: Clinical, histopathological and molecular correlates., PMID:39405803
LncRNA Pvt1 aggravates cardiomyocyte apoptosis via the microRNA-216/Ccnd3 axis., PMID:39398060
Gaucher-like crystal-storing histiocytosis associated with kappa chain myeloma: A case report with next generation sequencing study., PMID:39357187
Palbociclib in Solid Tumor Patients With Genomic Alterations in the cyclinD-cdk4/6-INK4a-Rb Pathway: Results From National Cancer Institute-Children's Oncology Group Pediatric Molecular Analysis for Therapy Choice Trial Arm I (APEC1621I)., PMID:39298716
Testosterone-Induced H3K27 Deacetylation Participates in Granulosa Cell Proliferation Suppression and Pathogenesis of Polycystic Ovary Syndrome., PMID:39243944
Genomic analysis reveals molecular characterization of CD30+ and CD30- extranodal natural killer/T-cell lymphomas (ENKTLs)., PMID:39187207
PRAME promotes proliferation of multiple myeloma cells through CTMP/Akt/p21/CCND3 axis by ubiquitinating CTMP and p21., PMID:39071619
Post-GWAS Validation of Target Genes Associated with HbF and HbA2 Levels., PMID:39056767
Analysis of CCND3 mutations in diffuse large B-cell lymphoma., PMID:38886191
Defining the heterogeneous molecular landscape of lung cancer cell responses to epigenetic inhibition., PMID:38853901
The application of proteomics and phosphoproteomics to reveal the molecular mechanism of salidroside in ameliorating myocardial hypoxia., PMID:38737233
A rare case of TFEB/6p21/VEGFA-amplified renal cell carcinoma diagnosed by whole-exome sequencing: clinicopathological and genetic feature report and literature review., PMID:38730456
Molecular Pathogenesis of Multiple Myeloma: Clinical Implications., PMID:38199896
A rare case of fluid overload-associated large B-cell lymphoma and antigen loss at relapse., PMID:38175437
The Cyclin D3 Protein Enforces Monogenic TCRβ Expression by Mediating TCRβ Protein-Signaled Feedback Inhibition of Vβ Recombination., PMID:38117277
First-Line Ipatasertib, Atezolizumab, and Taxane Triplet for Metastatic Triple-Negative Breast Cancer: Clinical and Biomarker Results., PMID:38060199
The genetic landscape of histologically transformed marginal zone lymphomas., PMID:37941429
Leukemic non-nodal cyclin D1- and SOX11-negative mantle cell lymphoma with CCND3::IGH rearrangement., PMID:37882866
BRD4 PROTAC degrader MZ1 exhibits anti-B-cell acute lymphoblastic leukemia effects via targeting CCND3., PMID:37594294
Circ_0001602 aggravates the progression of acute myeloid leukemia by regulating the miR-192-5p/ZBTB20 axis., PMID:37585722
IL-21 shapes germinal center polarization via light zone B cell selection and cyclin D3 upregulation., PMID:37466652
Limited clinical activity of palbociclib and ribociclib monotherapy in advanced cancers with cyclin D-CDK4/6 pathway alterations in the Dutch DRUP and Australian MoST trials., PMID:37424386
Analysis of the genomic landscape of primary central nervous system lymphoma using whole-genome sequencing in Chinese patients., PMID:37418076
Incidental Detection of TFEB-Amplified Renal Cell Carcinoma by Colocated Gene Amplification of CCND3 (6p21): A Case Report and Review of the Literature., PMID:37394760
Knocking down NSUN5 inhibits the development of clear cell renal cell carcinoma by inhibiting the p53 pathway., PMID:37263638
Inhibition of USP10 induces myeloma cell apoptosis by promoting cyclin D3 degradation., PMID:37055530
Simplified algorithm for genetic subtyping in diffuse large B-cell lymphoma., PMID:37032379
High-grade B-cell lymphoma with concurrent MYC rearrangement and 11q aberrations: clinicopathologic, cytogenetic, and molecular characterization of 4 cases., PMID:36997031
Clinical Targeted Next-Generation Panel Sequencing Reveals MYC Amplification Is a Poor Prognostic Factor in Osteosarcoma., PMID:36996377
Targeting diacylglycerol kinase α impairs lung tumorigenesis by inhibiting cyclin D3., PMID:36965165
Metformin and thymoquinone co-treatment enhance 5-fluorouracil cytotoxicity by suppressing the PI3K/mTOR/HIF1α pathway and increasing oxidative stress in colon cancer cells., PMID:36929658
Cyanidin-3-O-Glucoside Rescues Zearalenone-Induced Apoptosis via the ITGA7-PI3K-AKT Signaling Pathway in Porcine Ovarian Granulosa Cells., PMID:36901882
Whole-Blood Gene Expression Profiles Associated with Mortality in Community-Acquired Pneumonia., PMID:36830965
Evolutionary history of transformation from chronic lymphocytic leukemia to Richter syndrome., PMID:36624313
Novel targeted treatments in hairy cell leukemia and other hairy cell-like disorders., PMID:36620555
NOTCH1 mutation in chronic lymphocytic leukaemia is associated with an enhanced cell cycle G1/S transition and specific cyclin overexpression: Preclinical ground for targeted inhibition., PMID:36573331
Losing CD45 and various B-cell markers in a case of MYC-driven pediatric high-grade B-cell lymphoma, not otherwise specified that transformed from Burkitt's lymphoma during rituximab-containing treatments: a case report., PMID:36383247
For research use only. Not for human or drug use.
