Catalog No.
YHD70001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Arg272
Predicted molecular weight
32.94 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P26367
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
AN2, Aniridia type II protein, Oculorhombin, PAX6, Paired box protein Pax-6
Gene expression study in the siRNA based aniridia cell model and in primary aniridia limbal epithelial cells following duloxetine and ritanserin treatment., PMID:40493651
Vimentin network dysregulation mediates neurite deficits in SNCA duplication Parkinson's patient-derived midbrain neurons., PMID:40479066
Interaction between long-range chromatin regulators Nipbl & Isl1 synergistically drives heart defects in mice., PMID:40475661
Parallel sensory compensation following independent subterranean colonization by groundwater salamanders (Eurycea)., PMID:40460121
DLK1-expressing neural progenitor cells promote tissue repair and functional recovery after cervical spinal cord injury., PMID:40448964
Molecular insights into region-specific sexual dichromatism: Comparative transcriptome analysis of red cheek pigmentation in zebra finches., PMID:40354322
Medulloblastoma's master regulators and their association with patients' risk., PMID:40348787
Artesunate Enhances Sensitivity of Renal Cancer Cells to Sunitnib by Mediating Tripartite Motif Containing 24-Induced Ubiquitination of Paired Box 6., PMID:40346910
Effect of isolated keratin 3 knockdown on gene expression of primary limbal epithelial cells without and with inflammatory stimuli., PMID:40334825
Variant-specific disruption to notch signalling in PAX6 microphthalmia and aniridia patient-derived hiPSC optic cup-like organoids., PMID:40280197
Pax6 and Pax7 in the Central Nervous System of Cladistian Fishes: A Comprehensive Expression Analysis., PMID:40275424
Pax6 Directly Regulates the Raver2/sFlt-1 Expression in Corneal Epithelial Cells to Maintain the Cornea's Avascular Privilege., PMID:40249603
Myelin regulatory factor (MYRF) is a critical early regulator of retinal pigment epithelial development., PMID:40233131
Coexistence of congenital lacrimal gland agenesis and congenital aniridia: Case report., PMID:40226226
PAX3 expression patterns in ocular surface melanocytes., PMID:40216818
Inducing mononuclear cells of patients with CADASIL to construct a CSVD disease model., PMID:40176124
Efficient Fabrication of Human Corneal Stromal Cell Spheroids and Promoting Cell Stemness Based on 3D-Printed Derived PDMS Microwell Platform., PMID:40149974
Assessing Splicing Variants in the PAX6 Gene: A Comprehensive Minigene Approach., PMID:40133207
Decreased PAX6 and DSG1 Protein Expression in Corneal Epithelium of Patients with Epithelial Basal Membrane Dystrophy, Salzmann Nodular Degeneration, and Pterygium., PMID:40094891
Novel compound heterozygous variants in SIX6 cause a PAX2 like Dysplastic Optic Disc with macular abnormalities without coexistent microphthalmia or cataract., PMID:40083070
Derivation of functional neurons from induced pluripotent stem cells using a simple neuromesodermal progenitor generation and rapid spinal cord neuron differentiation process., PMID:40080267
Effects of Complex I Inhibition on the Architecture of Neural Rosettes Differentiated from Human-Induced Pluripotent Stem Cells., PMID:40079171
XEN 63 in a case of refractory glaucoma secondary to microphthalmia and aphakia., PMID:40058695
A novel, rapidly progressive ataxia due to a spontaneous Myo5a mutation in mice impairs transport proteins and alters mitochondria., PMID:40022605
A method for siRNA-mediated knockdown of target genes in RA-induced neurogenesis using P19 cells., PMID:39991434
Development of the early fetal human thalamus: from a protomap to emergent thalamic nuclei., PMID:39990522
Crosstalk between signaling pathways (Rho/ROCK, TGF-β and Wnt/β-Catenin Pathways/ PI3K-AKT-mTOR) in Cataract: A Mechanistic Exploration and therapeutic strategy., PMID:39965745
Stiffness Regulates the Morphology and Stemness of Limbal Niche Cells Through Unique nYAP/cYAP Translocation., PMID:39951297
Pax6 regulates neuronal migration and cell proliferation via interacting with Wnt3a during cortical development., PMID:39922861
Analysis of downstream targets of PAX6 and LHX2, fundamental regulators of the developing mammalian neocortex., PMID:39912400
Gene expression differences in the olfactory bulb associated with differential social interactions and olfactory deficits in Pax6 heterozygous mice., PMID:39902612
Deciphering the dynamic single-cell transcriptional landscape in the ocular surface ectoderm differentiation system., PMID:39872440
Exome sequencing identifies existing and novel variants in a South African cohort presenting with anterior segment dysgenesis., PMID:39870121
Sonic Hedgehog Determines Early Retinal Development and Adjusts Eyeball Architecture., PMID:39859210
Dual-stimuli-responsive nanoparticles for the co-delivery of small molecules to promote neural differentiation of human iPSCs., PMID:39815767
Analysis of mouse lens morphological and proteomic abnormalities following depletion of βB3-crystallin., PMID:39803551
Patient-derived cornea organoid model to study metabolomic characterization of rare disease: aniridia-associated keratopathy., PMID:39794714
Expression of PAX6 and Keratocyte-Characteristic Markers in Human Limbal Stromal Cells of Congenital Aniridia and Healthy Subjects, In Vitro., PMID:39791356
Augmentation of neural stem cell proliferation and enhanced differentiation toward neural and oligodendroglia lineages through sonic hedgehog pathway: Cross-activation of Notch1 and SOX10., PMID:39756602
Efficient genome editing in medaka (Oryzias latipes) using a codon-optimized SaCas9 system., PMID:39743295
Impact of c-JUN deficiency on thalamus development in mice and human neural models., PMID:39707500
Impact of photobiomodulation on neural embryoid body formation from immortalized adipose-derived stem cells., PMID:39707453
Examination of the Corneal Endothelium in Patients With Congenital Aniridia With a PAX6 Mutation Using In Vivo Confocal Laser Scanning Microscopy., PMID:39670973
Regulation of corneal epithelial differentiation: miR-141-3p promotes the arrest of cell proliferation and enhances the expression of terminal phenotype., PMID:39642122
A human-like model of aniridia-associated keratopathy for mechanistic and therapeutic studies., PMID:39625791
Molecular mechanism of METTL14-mediated m6A modification regulating microglial function post ischemic stroke., PMID:39622391
Promoter hypermethylation-mediated downregulation of PAX6 promotes tumor growth and metastasis during the progression of liver cancer., PMID:39614377
Conditional Immortalization Using SV40 Large T Antigen and Its Effects on Induced Pluripotent Stem Cell Differentiation Toward Retinal Progenitor Cells., PMID:39611948
Two coacting shadow enhancers regulate twin of eyeless expression during early Drosophila development., PMID:39607769
PAX6 is a useful marker for pancreatic origin of neuroendocrine neoplasms: A tissue microarray study evaluating more than 19,000 tumors from 150 different tumor types., PMID:39571690
For research use only. Not for human or drug use.
