Catalog No.
YHD71801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Leu52
Predicted molecular weight
32.95 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P26678
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PLN, Cardiac phospholamban, PLB
Glyoxal is a superior fixative to formaldehyde in promoting antigenicity and structural integrity in murine cardiac tissues., PMID:40485774
Expression and clinical significance of programmed cell death protein 1/programmed death-ligand 1 in non-small cell lung cancer patients with rare mutations of epidermal growth factor receptor gene: A retrospective cohort study., PMID:40469712
Immune perturbations in human pancreas lymphatic tissues prior to and after type 1 diabetes onset., PMID:40383826
AEOL-induced NRF2 activation and DWORF overexpression mitigate myocardial I/R injury., PMID:40375185
RBFOX1 Regulates Calcium Signaling and Enhances SERCA2 Translation., PMID:40358188
Harnessing Kupffer Cell Metabolic Rewiring: Rapamycin-Gliadin Nanoparticle as a Pivotal Strategy for Immune Tolerance in Celiac Disease., PMID:40302617
Additional genetic variants in cardiomyopathy patients with the pathogenic PLN p.(Arg14del) founder variant., PMID:40222661
Melanocortin-1 receptor expression as a predictive factor for postoperative outcomes in melanoma patients: a retrospective study., PMID:40213552
Cre recombinase affects calcium dynamics already in young mice., PMID:40206076
Subtherapeutic lithium supplementation causes physiological eccentric cardiac hypertrophy in young-adult wild-type male mice., PMID:40170524
Metformin prevents diabetes development in type 1 diabetes models via suppression of mTOR and STAT3 signaling in immune cells., PMID:40148472
Clinical Role of Pre-ablation Stimulated Thyroglobulin and Thyroid-Stimulating Hormone Ratio for Radioactive Iodine Treatment in Adults with Papillary Thyroid Cancer., PMID:40147171
Intratracheal Delivery of a Phospholamban Decoy Peptide Attenuates Cardiac Damage Following Myocardial Infarction., PMID:40141290
The costs of acromegaly management in Poland - analysis from one centre., PMID:40071804
Identification of disease-specific pathways and modifiers in phospholamban R14del cardiomyopathy: rationale, design and baseline characteristics of DECIPHER-PLN cohort., PMID:40048085
Humanized FcεRI Expressed on Mouse Eosinophils Mediates IgE-Facilitated Eosinophil Antigen Presentation., PMID:39996772
Deficiency in nucleoside diphosphate kinase B leads to endothelial activation of the hexosamine biosynthesis pathway and cardiac dysfunction., PMID:39985023
Efficiency of QM/MM optimization and fragment molecular orbital calculations for investigating interactions between zinc metalloprotease and its inhibitors., PMID:39983458
In silico molecular docking and molecular dynamic simulation of agarwood compounds with molecular targets of Alzheimer's disease ., PMID:39931160
Protective role of triiodothyronine in sepsis‑induced cardiomyopathy through phospholamban downregulation., PMID:39821325
Unraveling calcium dysregulation and autoimmunity in immune mediated rippling muscle disease., PMID:39819455
From Ca2+ dysregulation to heart failure: β-adrenoceptor activation by RKIP postpones molecular damages and subsequent cardiac dysfunction in mice carrying mutant PLNR9C by correction of aberrant Ca2+-handling., PMID:39742932
THE INFLUENCE OF BIFIDOBACTERIUM ANIMALIS AND LECTIN OF B. SUBTILIS IMV B-7724 ON THE ANTITUMOR IMMUNE RESPONSE OF MICE WITH EHRLICH ADENOCARCINOMA., PMID:39704458
Placental extracellular vesicles from women with severe preeclampsia alter calcium homeostasis in cardiomyocytes: an ex vivo study., PMID:39652412
Nanoparticulate drug combination inhibits DNA damage repair and PD-L1 expression in BRCA-mutant and wild type triple-negative breast cancer., PMID:39615752
Electrophysiological Phenotype-Genotype Study of Sustained Monomorphic Ventricular Tachycardia in Inherited, High Arrhythmic Risk, Left Ventricular Cardiomyopathy., PMID:39611258
Staphylococcus epidermidis ST2 strains associated with bloodstream infections contain a unique mobile genetic element encoding a plasmin inhibitor., PMID:39560391
β-adrenergic regulation of Ca2+ signaling in heart cells., PMID:39539286
Intracellular delivery of a phospholamban-targeting aptamer using cardiomyocyte-internalizing aptamers., PMID:39536855
The phospholamban R14del generates pathogenic aggregates by impairing autophagosome-lysosome fusion., PMID:39527246
Myocardial Posttranscriptional Landscape in Peripartum Cardiomyopathy., PMID:39513265
Bexotegrast Shows Dose-Dependent Integrin αvβ6 Receptor Occupancy in Lungs of Participants with Idiopathic Pulmonary Fibrosis: A Phase 2, Open-Label Clinical Trial., PMID:39499805
Elucidating the roles of SOD3 correlated genes and reactive oxygen species in rare human diseases using a bioinformatic-ontology approach., PMID:39480826
Clinical findings, prognostic factors, and outcome of protein-losing nephropathy in cats: A retrospective study., PMID:39481914
Mefloquine-induced conformational shift in Cx36 N-terminal helix leading to channel closure mediated by lipid bilayer., PMID:39455592
Unbiased complexome profiling and global proteomics analysis reveals mitochondrial impairment and potential changes at the intercalated disk in presymptomatic R14Δ/+ mice hearts., PMID:39446877
Cinnamaldehyde Alleviates Alveolar Epithelial Cell Injury in ALI by Inhibiting the CaMKII Pathway., PMID:39316262
Reassessing the Mechanisms of PLN-R14del Cardiomyopathy: From Calcium Dysregulation to S/ER Malformation., PMID:39297138
A Cautionary Tale of Hypertrophic Cardiomyopathy-From "Benign" Left Ventricular Hypertrophy to Stroke, Atrial Fibrillation, and Molecular Genetic Diagnostics: A Case Report and Review of Literature., PMID:39273332
A dual αvβ1/αvβ6 integrin inhibitor Bexotegrast (PLN-74809) ameliorates organ injury and fibrogenesis in fibrotic kidney disease., PMID:39243926
Probing the formation of a hetero-dimeric membrane transport complex with dual in vitro and in silico mutagenesis., PMID:39156929
Pathological mutations in the phospholamban cytoplasmic region affect its topology and dynamics modulating the extent of SERCA inhibition., PMID:38986894
Brigatinib in NF2-Related Schwannomatosis with Progressive Tumors., PMID:38904277
A Comprehensive Analysis of Non-Desmosomal Rare Genetic Variants in Arrhythmogenic Cardiomyopathy: Integrating in Padua Cohort Literature-Derived Data., PMID:38892455
Pharmacological inhibition of tyrosine protein-kinase 2 reduces islet inflammation and delays type 1 diabetes onset in mice., PMID:38766166
Chemical Composition and Elements Concentration of Fillet, Spine and Bones of Common Carp (Cyprinus carpio) in Relation to Nutrient Requirements for Minerals., PMID:38731315
Patterns of Failure After Prostate-Only Radiotherapy in High-Risk Prostate Cancer: Implications for Refining Pelvic Nodal Contouring Guidelines., PMID:38664178
Mitigation of Stress-induced Structural Remodeling and Functional Deficiency in iPSC-CMs with PLN R9C Mutation by Promoting Autophagy., PMID:38659742
For research use only. Not for human or drug use.
