Catalog No.
YHD57701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln22-Leu193
Predicted molecular weight
21.30 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P23435
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Cerebellin-1, CER, Precerebellin, CBLN1
Atypical Cadherin FAT2 Is Required for Synaptic Integrity and Motor Behaviors., PMID:40393806
Identification of Deregulated miRNAs and mRNAs Involved in Tumorigenesis and Detection of Glioblastoma Patients Applying Next-Generation RNA Sequencing., PMID:40143207
D-Serine disrupts Cbln1 and GluD1 interaction and affects Cbln1-dependent synaptic effects and nocifensive responses in the central amygdala., PMID:39890638
GluN2D-containing NMDA receptors in parvalbumin neurons in the nucleus accumbens regulate nocifensive responses in neuropathic pain., PMID:39733959
Stepwise molecular specification of excitatory synapse diversity onto cerebellar Purkinje cells., PMID:39658623
Lack of evidence for direct ligand-gated ion channel activity of GluD receptors., PMID:39052831
Intravenous recombinant cerebellin 1 treatment restores signalling by spinal glutamate delta 1 receptors and mitigates chronic pain., PMID:38044332
Key genes and potential drugs in age-related hearing loss: transcriptome analysis of cochlear hair cells in old mice., PMID:37605587
Cerebellin-neurexin complexes instructing synapse properties., PMID:37209532
MUM1L1 as a Tumor Suppressor and Potential Biomarker in Ovarian Cancer: Evidence from Bioinformatics Analysis and Basic Experiments., PMID:36856181
Cbln1 Directs Axon Targeting by Corticospinal Neurons Specifically toward Thoraco-Lumbar Spinal Cord., PMID:36823038
Construction and validation of a cuproptosis-related prognostic model for glioblastoma., PMID:36814929
Cbln1 regulates axon growth and guidance in multiple neural regions., PMID:36395107
Distinct neurexin-cerebellin complexes control AMPA- and NMDA-receptor responses in a circuit-dependent manner., PMID:36205393
In vivo nanoscopic landscape of neurexin ligands underlying anterograde synapse specification., PMID:36007521
Association of Genetically Predicted BCAA Levels with Muscle Fiber Size in Athletes Consuming Protein., PMID:35327951
Dysfunction of Glutamate Delta-1 Receptor-Cerebellin 1 Trans-Synaptic Signaling in the Central Amygdala in Chronic Pain., PMID:34685624
Family-Based Cohort Association Study of PRKCB1, CBLN1 and KCNMB4 Gene Polymorphisms and Autism in Polish Population., PMID:34562210
Multiomic Analyses of Dopaminergic Neurons Isolated from Human Substantia Nigra in Parkinson's Disease: A Descriptive and Exploratory Study., PMID:34528139
The porcine cerebellin gene family., PMID:34274480
Glutamate Delta-1 Receptor Regulates Inhibitory Neurotransmission in the Nucleus Accumbens Core and Anxiety-Like Behaviors., PMID:34173171
Cerebellin-2 regulates a serotonergic dorsal raphe circuit that controls compulsive behaviors., PMID:34158618
Long noncoding RNA PM maintains cerebellar synaptic integrity and Cbln1 activation via Pax6/Mll1-mediated H3K4me3., PMID:34111112
Destroy the old to build the new: Activity-dependent lysosomal exocytosis in neurons., PMID:33845090
The long noncoding RNA Synage regulates synapse stability and neuronal function in the cerebellum., PMID:33762741
GluD2- and Cbln1-mediated competitive interactions shape the dendritic arbors of cerebellar Purkinje cells., PMID:33352118
Identification of Potential Biomarkers of Polycystic Ovary Syndrome via Integrated Bioinformatics Analysis., PMID:33067753
A synthetic synaptic organizer protein restores glutamatergic neuronal circuits., PMID:32855309
Adiponectin and related C1q/TNF-related proteins bind selectively to anionic phospholipids and sphingolipids., PMID:32632018
Nerve impulse transmission pathway-focused genes expression analysis in patients with primary hypothyroidism and autoimmune thyroiditis., PMID:32597152
Integrative analysis of DNA methylation-driven genes for the prognosis of lung squamous cell carcinoma using MethylMix., PMID:32218699
Striatal glutamate delta-1 receptor regulates behavioral flexibility and thalamostriatal connectivity., PMID:31945419
Serum amphiregulin and cerebellin-1 levels in severe preeclampsia., PMID:31630583
Toxicogenomic analyses of the effects of BDE-47/209, TBBPA/S and TCBPA on early neural development with a human embryonic stem cell in vitro differentiation system., PMID:31326446
Activity-Dependent Secretion of Synaptic Organizer Cbln1 from Lysosomes in Granule Cell Axons., PMID:31072786
Expression of new genes in vertebrate tooth development and p63 signaling., PMID:30875130
Evidence for generative homology of cerebellum and cerebellum-like structures in an elasmobranch fish based on Pax6, Cbln1 and Grid2 expression., PMID:29888788
Glycosylation of Cblns attenuates their receptor binding., PMID:29782851
Spinal injection of newly identified cerebellin-1 and cerebellin-2 peptides induce mechanical hypersensitivity in mice., PMID:29705514
Genetic Ablation of All Cerebellins Reveals Synapse Organizer Functions in Multiple Regions Throughout the Brain., PMID:29691328
Improvement of cerebellar ataxic gait by injecting Cbln1 into the cerebellum of cbln1-null mice., PMID:29670152
Two Classes of Secreted Synaptic Organizers in the Central Nervous System., PMID:29166241
Branched-chain amino acids and Alzheimer's disease: a Mendelian randomization analysis., PMID:29051501
Can cerebellin and renalase measurements contribute to the elimination of false positive results in pheochromocytoma and paraganglioma diagnoses?, PMID:28915965
Cbln1 and Cbln4 Are Structurally Similar but Differ in GluD2 Binding Interactions., PMID:28877468
Cerebellins are differentially expressed in selective subsets of neurons throughout the brain., PMID:28714144
Follicular fluid cerebellin and betatrophin regulate the metabolic functions of growing follicles in polycystic ovary syndrome., PMID:28428942
Autism gene Ube3a and seizures impair sociability by repressing VTA Cbln1., PMID:28297715
The C1q complement family of synaptic organizers: not just complementary., PMID:28219683
Maternal Immune Activation Causes Behavioral Impairments and Altered Cerebellar Cytokine and Synaptic Protein Expression., PMID:28102228
For research use only. Not for human or drug use.
