Catalog No.
YHD58601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly610-Lys802
Predicted molecular weight
24.80 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P23497
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Nuclear autoantigen Sp-100, Speckled 100 kDa, Nuclear dot-associated Sp100 protein, SP100
Prevalence and clinical significance of autoantibodies to sulphite oxidase and glycogen phosphorylase in Chinese primary biliary cholangitis patients., PMID:40515960
Anti-RPL30 as a novel biomarker for enhanced diagnosis of autoantibody-negative primary biliary cholangitis., PMID:40495948
Autoimmune Hepatitis-Primary Biliary Cholangitis Overlap in a Case of Pulmonary Arterial Hypertension and Sjögren's Syndrome: Occam's Razor or Hickam's Dictum?, PMID:40330361
Increased IgG Levels at Diagnosis Are Associated With Worse Prognosis of Patients With Primary Biliary Cholangitis., PMID:40125888
Discovery of novel serum peptide biomarkers for cholangiocarcinoma recurrence through MALDI-TOF MS and LC-MS/MS peptidome analysis., PMID:39833435
Development and nomogram prediction of early postoperative recurrence in hepatocellular carcinoma based on preoperative CT imaging radiomic features and serum features related to microvascular infiltration., PMID:39816033
Sp140L Is a Novel Herpesvirus Restriction Factor., PMID:39713285
Identification and RT-qPCR Validation of Biomarkers Based on Butyrate Metabolism-Related Genes to Predict Recurrent Miscarriage., PMID:39372587
Comparative proteomic analysis of PK-15 cells infected with wild-type strain and its EP0 gene-deleted mutant strain of pseudorabies virus., PMID:39083206
Clinical Performance of the Line Immunoassay and Digital Liquid Chip Method for Detecting Autoimmune Liver Disease Autoantibodies., PMID:38830630
Frontiers in Plasma Proteome Profiling Platforms: Innovations and Applications., PMID:38645164
SP140 inhibitor suppressing TRIM22 expression regulates glioma progress through PI3K/AKT signaling pathway., PMID:38468469
Diagnostic value of quantitative chemiluminescence immunoassay for anti-gp210 and anti-sp100 antibodies in primary biliary cholangitis., PMID:38443325
Construction of a TF-miRNA-mRNA Regulatory Network for Diabetic Nephropathy., PMID:38374020
Clinical performance of AMA-M2, anti-gp210 and anti-sp100 antibody levels in primary biliary cholangitis: When detected by multiplex bead-based flow fluorescent immunoassay., PMID:38270327
Autoantibodies profile in autoimmune liver diseases and chronic viral hepatitis., PMID:38224225
Role of Influenza A virus protein NS1 in regulating host nuclear body ND10 complex formation and its involvement in establishment of viral pathogenesis., PMID:38166085
Histone lactylation-boosted ALKBH3 potentiates tumor progression and diminished promyelocytic leukemia protein nuclear condensates by m1A demethylation of SP100A., PMID:38118002
Cytosolic nucleic acid sensing and mitochondrial transcriptomic changes as early triggers of metabolic disease in db/db mice., PMID:37979047
Autoimmune Markers in Primary Biliary Cholangitis., PMID:37945165
[Application Effect of Continuous Lumbar Cistern Fluid Drainage Combined With Decompressive Craniectomy in the Treatment of Severe Craniocerebral Injury]., PMID:37866966
Role of biochemical markers and autoantibodies in diagnosis of early-stage primary biliary cholangitis., PMID:37753365
Identification of urinary extracellular vesicles differentially expressed RNAs in diabetic nephropathy via whole-transcriptome integrated analysis., PMID:37738894
HSV-1 selectively packs the transcription factor Oct-1 into EVs to facilitate its infection., PMID:37396389
The transcriptional foundations of interferon-λ-mediated endometrial cell to uterine receptivity., PMID:37382172
A Novel Fusion Partner, SP100, Drives Nuclear Dot Localization of ALK in Epithelioid Fibrous Histiocytoma., PMID:37377191
Expression, prognostic value and mechanism of SP100 family in pancreatic adenocarcinoma., PMID:37354211
Serological markers of rheumatoid arthritis in patients with primary biliary cholangitis and the vice versa: A Tunisian study., PMID:37269587
Interplay between PML NBs and HIRA for H3.3 dynamics following type I interferon stimulus., PMID:37227756
The interactions between PML nuclear bodies and small and medium size DNA viruses., PMID:37127643
Correlation between individual autoantibodies and clinical features in primary biliary cholangitis: results of a retrospective longitudinal study., PMID:37116005
SOX2 downregulation of PML increases HCMV gene expression and growth of glioma cells., PMID:37058447
Role of autoantibodies in the clinical management of primary biliary cholangitis., PMID:37032725
[Utility of the detection of autoantibodies in autoinmune liver diseases using immunoblot]., PMID:38687521
Presence of anti-gp210 or anti-sp100 antibodies in AMA-positive patients may help support a diagnosis of primary biliary cholangitis., PMID:36610465
The Cajal body marker protein coilin is SUMOylated and possesses SUMO E3 ligase-like activity., PMID:39703804
K63-linked polyubiquitination of LGP2 by Riplet regulates RIG-I-dependent innate immune response., PMID:36515138
Performance of indirect immunofluorescence test and immunoblot tests in the evaluation of antinuclear and antimitochondrial antibodies., PMID:36422475
Promyelocytic Leukemia Protein Potently Restricts Human Cytomegalovirus Infection in Endothelial Cells., PMID:36233232
Sodium propionate improves cognitive and memory function in mouse models of Alzheimer's disease., PMID:36174844
The effect of serum IL-2 levels on the prognosis of primary biliary cholangitis-related liver failure and the preliminary exploration of its mechanism., PMID:36159788
A novel long noncoding RNA SP100-AS1 induces radioresistance of colorectal cancer via sponging miR-622 and stabilizing ATG3., PMID:35978049
Exploration of the Shared Gene Signatures between Myocardium and Blood in Sepsis: Evidence from Bioinformatics Analysis., PMID:35971449
PML Body Component Sp100A Restricts Wild-Type Herpes Simplex Virus 1 Infection., PMID:35353002
Molecular Cloning of Alternative Splicing Variants of the Porcine PML Gene and Its Expression Patterns During Japanese Encephalitis Virus Infection., PMID:34888375
Clinical impact of antibodies to Sp100 on a bacterial infection in patients with primary biliary cholangitis., PMID:34623692
Changes of Serum IgG Glycosylation Patterns in Primary Biliary Cholangitis Patients., PMID:34248947
Anti-gp210 and anti-Sp100 antibodies in primary biliary cholangitis., PMID:34090832
Towards the characterization of the hidden world of small proteins in Staphylococcus aureus, a proteogenomics approach., PMID:34061833
Clinicopathological and molecular characterization of chromophobe hepatocellular carcinoma., PMID:34036718
For research use only. Not for human or drug use.
