Catalog No.
YHD54301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala19-Lys283
Predicted molecular weight
32.55 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P22748
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Carbonic anhydrase 4, Carbonate dehydratase IV, CA-IV, CA4, Carbonic anhydrase IV
Selective Vulnerability of Hippocampi for Nitric Oxide Synthases in Alzheimer's Disease Pathology and Cognitive Abilities., PMID:40504299
Gα Protein Mediates High-Concentration CO2-Induced Stomata Closure Through Interaction With Carbonic Anhydrase to Promote Guard Cell Hydrogen Peroxide Production in Arabidopsis., PMID:40421746
Advanced localized gene transfection and drug delivery using an injectable in situ forming dextran-based hydrogel against breast cancer., PMID:40414324
Sequence and trajectory of early Alzheimer's disease-related tau inclusions in the hippocampal formation of cases without amyloid-β deposits., PMID:40407905
Time-resolved mitochondrial screen identifies regulatory components of oxidative metabolism., PMID:40301572
Exome sequencing of a Portuguese cohort of early-onset Alzheimer's disease implicates the X-linked lysosomal gene GLA., PMID:40185916
Molecular pathways and diagnosis in spatially resolved Alzheimer's hippocampal atlas., PMID:40168986
Selective tubulin-binding drugs induce pericyte phenotype switching and anti-cancer immunity., PMID:40140727
Optimization of Split Feeding Strategy for Laying Hens Through a Response Surface Model., PMID:40076034
Delayed treatment with TGF-β1 associated neuroprotection in trimethyltin-induced hippocampal neurodegeneration., PMID:40049360
Moringa oleifera Leaf Extract Improves Cognitive Function in Rat Offspring Born to Protein-Deficient Mothers., PMID:40002759
Hippocampal mitophagy alterations in MAPT-associated frontotemporal dementia with parkinsonism., PMID:39994734
Discovery of novel thienopyridine indole derivatives as inhibitors of tubulin polymerization targeting the colchicine-binding site with potent anticancer activities., PMID:39874633
Synthesis and Biological Evaluation of New cis-Restricted Triazole Analogues of Combretastatin A-4., PMID:39860187
Mechanistic determinants and dynamics of cA6 synthesis in type III CRISPR-Cas effector complexes., PMID:39817514
Spatial proteomic differences in chronic traumatic encephalopathy, Alzheimer's disease, and primary age-related tauopathy hippocampi., PMID:39737785
Unveiling the substantial role of rutin in the management of drug-induced nephropathy using network pharmacology and molecular docking., PMID:39733639
Design, Synthesis and Biological Evaluation of 2-Phenyl Indole Analogues of OXi8006 as Colchicine Site Inhibitors of Tubulin Polymerization and Vascular Disrupting Agents., PMID:39667146
Antiviral signaling of a type III CRISPR-associated deaminase., PMID:39666823
Design, synthesis and biological evaluation of novel diaryl-substituted fused nitrogen heterocycles as tubulin polymerization inhibitors to overcome multidrug resistance in vitro and in vivo., PMID:39662283
Bioinformatics analysis of colorectal cancer transcriptomic data reveals novel prognostic signature and potential biomarker genes., PMID:39644158
Histopathological evidence of cellular alterations in the dentate gyrus is associated with aberrant RB1CC1-ATG16L1 expression in the hippocampus among older adults with chronic schizophrenia: A pilot post-mortem study., PMID:39612766
Molecular Polymorphism of tau aggregates in Pick's disease., PMID:39605720
Synthesis and structure-activity relationship of boronic acid bioisosteres of combretastatin A-4 as anticancer agents., PMID:39546933
Combretastatin A-4 based compounds as potential anticancer agents: A review., PMID:39504638
A novel life for antitumor combretastatins: Recent developments of hybrids, prodrugs, combination therapies, and antibody-drug conjugates., PMID:39500065
The CRISPR-associated adenosine deaminase Cad1 converts ATP to ITP to provide antiviral immunity., PMID:39471810
Cellular responses to neoadjuvant FOLFOX6-bevacizumab treatment in colorectal cancers analyzed by single-cell transcriptome analysis., PMID:39471526
Unraveling Neurotoxicity Discrepancies: Comparative In vitro and In vivo Analysis of Colistin and Polymyxin B and the Underlying Mechanisms., PMID:39467983
Filament formation activates protease and ring nuclease activities of CRISPR Lon-SAVED., PMID:39362215
Light Color Regulation of Photosynthetic Antennae Biogenesis in Marine Phytoplankton., PMID:39361137
Construction of an artificial neural network diagnostic model and investigation of immune cell infiltration characteristics for idiopathic pulmonary fibrosis., PMID:39289672
The SAVED domain of the type III CRISPR protease CalpL is a ring nuclease., PMID:39166476
The associations of peripheral interleukin alterations and hippocampal subfield volume deficits in schizophrenia., PMID:39077921
Synthesis and Biological Evaluation of Novel 2-Aroyl Benzofuran-Based Hydroxamic Acids as Antimicrotubule Agents., PMID:39062759
Molecular basis for cA6 synthesis by a type III-A CRISPR-Cas enzyme and its conversion to cA4 production., PMID:38989619
Identification of a magnesium-binding site at the primary allosteric calcium sensor of the sodium-calcium exchanger: Implications for physiological regulation., PMID:38989557
Aptamer functionalized hypoxia-potentiating agent and hypoxia-inducible factor inhibitor combined with hypoxia-activated prodrug for enhanced tumor therapy., PMID:38969157
Structural insight into the Csx1-Crn2 fusion self-limiting ribonuclease of type III CRISPR system., PMID:38967023
Synthesis and biological evaluation of 4-phenyl-5-quinolinyl substituted isoxazole analogues as potent cytotoxic and tubulin polymerization inhibitors against ESCC., PMID:38901104
Protein and metabolic profiles of tyrosine kinase inhibitors co-resistant liver cancer cells., PMID:38835670
Design, concise synthesis and evaluation of novel amide-based combretastatin A-4 analogues as potent tubulin inhibitors., PMID:38806101
Design, synthesis of combretastatin A-4 piperazine derivatives as potential antitumor agents by inhibiting tubulin polymerization and inducing autophagy in HCT116 cells., PMID:38759453
Longitudinal in vivo cationic contrast-enhanced computed tomography classifies equine articular cartilage injury and repair., PMID:38715519
Neuroinflammation is associated with Alzheimer's disease co-pathology in dementia with Lewy bodies., PMID:38715119
Resistance exercise effects on hippocampus subfield volumes and biomarkers of neuroplasticity and neuroinflammation in older adults with low and high risk of mild cognitive impairment: a randomized controlled trial., PMID:38478179
CRISPR antiphage defence mediated by the cyclic nucleotide-binding membrane protein Csx23., PMID:38471818
Design and biological evaluation of dual tubulin/HDAC inhibitors based on millepachine for treatment of prostate cancer., PMID:38452727
Unveiling the genetic basis of Fusarium wilt resistance in chickpea using GWAS analysis and characterization of candidate genes., PMID:38327700
Interaction of Cecropin A (1-7) Analogs with DNA Analyzed by Multi-spectroscopic Methods., PMID:38265732
For research use only. Not for human or drug use.
