Catalog No.
YHD54101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser467-Ala817
Predicted molecular weight
40.29 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P22735
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
KTG, Transglutaminase K, Epidermal TGase, Protein-glutamine gamma-glutamyltransferase K, TGK, TGase K, TGase-1, TGM1, TG(K), Transglutaminase-1
Novel compound heterozygous variants in TGM1 with the lethal neonatal collodion baby and autosomal recessive congenital ichthyosis., PMID:40119962
Aloe polysaccharide promotes keratinocyte proliferation, migration, and differentiation by upregulating the EGFR/PKC-dependent signaling pathways., PMID:40064981
Potential activity of chicken amniotic fluid in epidermal development by promoting keratinocyte differentiation., PMID:40020982
The hematopoietic tissue of the freshwater crayfish, Pacifastacus leniusculus: organization and expression analysis., PMID:39753778
Revealing the Therapeutic Potential: Investigating the Impact of a Novel Witch Hazel Formula on Anti-Inflammation and Antioxidation., PMID:39575475
Molecular analysis of inherited disorders of cornification in polish patients show novel variants and functional data and provokes questions on the significance of secondary findings., PMID:39501396
ISOLATION AND PURIFICATION OF TRANSGLUTAMINASE 1 USING BIOCHEMICAL TECHNIQUES., PMID:39441279
Transglutaminase 1: Emerging Functions beyond Skin., PMID:39408635
A cellular disease model toward gene therapy of TGM1-dependent lamellar ichthyosis., PMID:39234443
Skin barrier, phenotypic and genotypic characterisation of autosomal recessive ichthyosis in TGM1-deficient Jack Russell Terriers and response to topical ceramide., PMID:39118209
The importance of stratum corneum ω-linoleoyloxyacylceramides in human skin barrier health: their biochemistry, processing enzymes and metabolites involved in corneocyte lipid envelope maturation., PMID:39113292
Evaluation of the anti-aging potential of acetyl tripeptide-30 citrulline in cosmetics., PMID:39103061
Sphingolipid-Enriched Porcine Placental Extract Promotes the Expression of Structural Genes and Desquamation Enzyme Genes in Cultured Human Keratinocytes., PMID:38945844
Superior COL7A1 and TGM1 gene expression in difficult-to-transfect skin cell mediated by highly branched poly(β-amino esters) through stepwise fractionation., PMID:38643938
Cross-Sectional Study on Autosomal Recessive Congenital Ichthyoses: Association of Genotype with Disease Severity, Phenotypic, and Ultrastructural Features in 74 Italian Patients., PMID:38588653
In vitro generation of epidermal keratinocytes from human CD34-positive hematopoietic stem cells., PMID:38502372
Substrate profiling of human transglutaminase 1 using cDNA display and next-generation sequencing., PMID:38479783
A pan-cancer analysis of the oncogenic and immunological roles of transglutaminase 1 (TGM1) in human cancer., PMID:38472489
Tofacitinib ameliorates skin inflammation in a patient with severe autosomal recessive congenital ichthyosis., PMID:38469681
Prenatal ultrasound detection of collodion membrane in association with an autosomal recessive congenital ichthyosis due to transglutaminase 1 deficiency., PMID:38156659
Proteomics analysis of the brain from a Gaucher disease mouse identifies pathological pathways including a possible role for transglutaminase 1., PMID:38071490
Novel Compound Heterozygous Mutations of TGM1 Gene Identified in a Turkish Collodion Baby Diagnosed with Non-Bullous Congenital Ichthyosiform Erythroderma., PMID:38061711
Whole exome sequencing identifies novel pathogenic variants in TGM1 and ALOX12B in patients with hereditary ichthyosis., PMID:38060040
Cornification of keratinocytes is associated with differential changes in the catalytic activity and the immunoreactivity of transglutaminase-1., PMID:38057394
Skin hydration modulatory activities of Ficus deltoidea extract., PMID:38000761
Production of Tissue-Engineered Skin Substitutes for Clinical Applications: Elimination of Serum., PMID:37628718
Ophthalmic findings in patients with autosomal recessive lamellar ichthyosis due to TGM1 mutations in an isolated population., PMID:37542530
Non-invasive Microneedle Application Increases Ceramide and Natural Moisturizing Factors in a Reconstructed Human Skin Model., PMID:37518093
The effect of long-term cigarette smoking on selected skin barrier proteins and lipids., PMID:37463939
Human epidermis organotypic cultures, a reproducible system recapitulating the epidermis in vitro., PMID:37114406
Antiphotoaging and Skin-Protective Activities of Ardisia silvestris Ethanol Extract in Human Keratinocytes., PMID:36904025
Investigations into the FLG Null Phenotype: Showcasing the Methodology for CRISPR/Cas9 Editing of Human Keratinocytes., PMID:36893939
Biallelic mutations in FLG, TGM1, and STS genes segregated with different types of ichthyoses in eight families of Pakistani origin., PMID:36789964
Evaluating different levels of papain as texture modifying agent in bovine meat loaf containing transglutaminase., PMID:36702066
Identification and In Silico Analysis of a Homozygous Nonsense Variant in TGM1 Gene Segregating with Congenital Ichthyosis in a Consanguineous Family., PMID:36676727
Moisturizing at a molecular level - The basis of Corneocare., PMID:36453857
Deep Association between Transglutaminase 1 and Tissue Eosinophil Infiltration Leading to Nasal Polyp Formation and/or Maintenance with Fibrin Polymerization in Chronic Rhinosinusitis with Nasal Polyps., PMID:36361742
Defining the optimum strategy for identifying adults and children with coeliac disease: systematic review and economic modelling., PMID:36321689
Design of an Integrated Microvascularized Human Skin-on-a-Chip Tissue Equivalent Model., PMID:35928950
Screening and Research on Skin Barrier Damage Protective Efficacy of Different Mannosylerythritol Lipids., PMID:35889520
Successful Treatment of an Adult with Atopic Dermatitis and Lamellar Ichthyosis Using Dupilumab., PMID:35769328
Alpha-Keratin, Keratin-Associated Proteins and Transglutaminase 1 Are Present in the Ortho- and Parakeratinized Epithelium of the Avian Tongue., PMID:35741029
Compound Heterozygous Mutations in TGM1 Causing a Severe Form of Lamellar Ichthyosis: A Case Report., PMID:35698621
In Vitro Anti-Photoaging and Skin Protective Effects of Licania macrocarpa Cuatrec Methanol Extract., PMID:35631808
Decoy receptor 3 is involved in epidermal keratinocyte commitment to terminal differentiation via EGFR and PKC activation., PMID:35478210
Cytokeratin profile and keratinocyte gene expression in keratinized lid margins of patients with chronic Stevens-Johnson syndrome., PMID:35460363
Current Strategies for the Gene Therapy of Autosomal Recessive Congenital Ichthyosis and Other Types of Inherited Ichthyosis., PMID:35269649
Anti-Inflammatory, Antioxidant, Moisturizing, and Antimelanogenesis Effects of Quercetin 3-O-β-D-Glucuronide in Human Keratinocytes and Melanoma Cells via Activation of NF-κB and AP-1 Pathways., PMID:35008862
A gene-centric approach to biomarker discovery identifies transglutaminase 1 as an epidermal autoantigen., PMID:34911754
Identification of Chicken Transglutaminase 1 and In Situ Localization of Transglutaminase Activity in Avian Skin and Esophagus., PMID:34680960
For research use only. Not for human or drug use.
