Catalog No.
YHD48701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Phe361-His477
Predicted molecular weight
15.54 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P21918
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
DRD1L2, D(5) dopamine receptor, D(1B) dopamine receptor, D1beta dopamine receptor, DRD1B, DRD5, Dopamine D5 receptor
Subtype-specific dysregulation of biogenic amine-related genes and miRNAs in breast cancer: identification of DRD2, HRH2, and HRH4 as potential therapeutic targets in TNBC and HER2+ subtypes., PMID:40425926
Dopamine-driven increase in IL-1β in myeloid cells is mediated by differential dopamine receptor expression and exacerbated by HIV., PMID:40122818
DA-DRD5 signaling reprograms B cells to promote CD8+ T cell-mediated antitumor immunity., PMID:40023842
Chemokinergic and Dopaminergic Signalling Collaborates through the Heteromer Formed by CCR9 and Dopamine Receptor D5 Increasing the Migratory Speed of Effector CD4+ T-Cells to Infiltrate the Colonic Mucosa., PMID:39337509
Sex differences in sensitivity to fentanyl effects in mice: Behavioral and molecular findings during late adolescence., PMID:39013536
Expression Profiles of Dopamine-Related Genes and miRNAs Regulating Their Expression in Breast Cancer., PMID:38928253
Dopamine-driven Increase in IL-1β in Myeloid Cells is Mediated by Differential Dopamine Receptor Expression and Exacerbated by HIV., PMID:38915663
Theobromine improves hyperactivity, inattention, and working memory via modulation of dopaminergic neural function in the frontal cortex of spontaneously hypertensive rats., PMID:38713055
Broiler Heart Muscle Monoaminergic Receptors Alteration in Response to Chronic Heat Stress: Based on Transcription Analysis., PMID:38590690
The dopamine receptor D1 inhibitor, SKF83566, suppresses GBM stemness and invasion through the DRD1-c-Myc-UHRF1 interactions., PMID:38246990
Echinacoside stimulates myogenesis and ATP-dependent thermogenesis in the skeletal muscle via the activation of D1-like dopaminergic receptors., PMID:38215960
An inducible mouse model of heart failure targeted to cardiac Drd5 deficiency detonating mitochondrial oxidative stress., PMID:38164957
Behavioral, neurochemical and neuroimmune features of RasGEF1b deficient mice., PMID:38048936
Echinacoside Induces UCP1- and ATP-Dependent Thermogenesis in Beige Adipocytes via the Activation of Dopaminergic Receptors., PMID:37463854
Silencing of dopamine receptor D5 inhibits the browning of 3T3-L1 adipocytes and ATP-consuming futile cycles in C2C12 muscle cells., PMID:37140438
DNA methylation profiling reveals novel pathway implicated in cardiovascular diseases of diabetes., PMID:36875456
DRD1 and DRD4 are differentially expressed in breast tumors and breast cancer stem cells: pharmacological implications., PMID:36523297
Peroxiredoxin-4 and Dopamine D5 Receptor Interact to Reduce Oxidative Stress and Inflammation in the Kidney., PMID:36401517
The Role of Dopamine D3 Receptors in Tobacco Use Disorder: A Synthesis of the Preclinical and Clinical Literature., PMID:36173599
Relationship of DRD5 and MAO-B VNTR polymorphisms with paranoid and antisocial personality disorders in polydrug users., PMID:35961947
Immunogenomic Characteristics of Cell-Death-Associated Genes with Prognostic Implications in Bladder Cancer., PMID:35898507
Dopaminergic inhibition of human neutrophils is exerted through D1-like receptors and affected by bacterial infection., PMID:35897164
Dopamine Signaling Promotes Tissue-Resident Memory Differentiation of CD8+ T Cells and Antitumor Immunity., PMID:35802647
Dopamine receptor signaling regulates fibrotic activation of retinal pigmented epithelial cells., PMID:35544697
Anti-Tumor and Anti-Invasive Effects of ONC201 on Ovarian Cancer Cells and a Transgenic Mouse Model of Serous Ovarian Cancer., PMID:35372029
Polymorphisms of the dopamine metabolic and signaling pathways are associated with susceptibility to motor levodopa-induced complications (MLIC) in Parkinson's disease: a systematic review and meta-analysis., PMID:35079903
Expression of D5 dopamine receptors in the lateral ventricle walls during post-weaning rat development., PMID:34881789
miRNAs in the Expression Regulation of Dopamine-Related Genes and Proteins in Endometrial Cancer., PMID:34768458
c-Myc-activated intronic miR-210 and lncRNA MIR210HG synergistically promote the metastasis of gastric cancer., PMID:34767926
Dopamine promotes the progression of AML via activating NLRP3 inflammasome and IL-1β., PMID:34509315
Detection of six novel de novo mutations in individuals with low resilience to psychological stress., PMID:34492034
Dopamine receptor D2 on CD4+ T cells is protective against neuroinflammation and neurodegeneration in a mouse model of Parkinson's disease., PMID:34403737
An association study in the Taiwan Biobank elicits three novel candidates for cognitive aging in old adults: NCAM1, TTC12 and ZBTB20., PMID:34285142
DA-DRD5 signaling controls colitis by regulating colonic M1/M2 macrophage polarization., PMID:34001860
Ethanol inhibition of lateral orbitofrontal cortex neuron excitability is mediated via dopamine D1/D5 receptor-induced release of astrocytic glycine., PMID:33965399
miR-132 and miR-942 Expression Levels in Children with Attention Deficit and Hyperactivity Disorder: A Controlled Study., PMID:33888655
The Heteromeric Complex Formed by Dopamine Receptor D5 and CCR9 Leads the Gut Homing of CD4+ T Cells Upon Inflammation., PMID:33864900
Dopamine D5 receptor-mediated decreases in mitochondrial reactive oxygen species production are cAMP and autophagy dependent., PMID:33820956
Dopaminergic modulation of working memory and cognitive flexibility in a zebrafish model of aging-related cognitive decline., PMID:33676049
Metabolic and inflammatory reprogramming of macrophages by ONC201 translates in a pro-inflammatory environment even in presence of glioblastoma cells., PMID:33442873
Inhibition of striatal dopamine D5 receptor attenuates levodopa-induced dyskinesia in a rat model of Parkinson's disease., PMID:33422541
Lister hooded rats as a novel animal model of attention-deficit/hyperactivity disorder., PMID:33010392
Hypermethylation of DRD5 Promoter Is a Biomarker Across 12 Cancer Types., PMID:32907377
Screening natural inhibitors against upregulated G-protein coupled receptors as potential therapeutics of Alzheimer's disease., PMID:32900274
Characterization of Dopamine Receptor Associated Drugs on the Proliferation and Apoptosis of Prostate Cancer Cell Lines., PMID:32867661
Mechanism underpinning effects of Shichangpu (Rhizoma Acori Tatarinowii) on attention deficit hyperactivity disorder., PMID:32227770
The effects of dopamine receptor genes on the trajectories of sport participation from adolescence through young adulthood., PMID:32183536
A Neurofunctional Domains Approach to Evaluate D1/D5 Dopamine Receptor Partial Agonism on Cognition and Motivation in Healthy Volunteers With Low Working Memory Capacity., PMID:32055822
Dopamine Uses the DRD5-ARRB2-PP2A Signaling Axis to Block the TRAF6-Mediated NF-κB Pathway and Suppress Systemic Inflammation., PMID:32035036
Endurance and resistance training mitigate the negative consequences of depression on synaptic plasticity through different molecular mechanisms., PMID:31847639
For research use only. Not for human or drug use.
