Catalog No.
YHD50501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly371-Leu660
Predicted molecular weight
34.23 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P22223
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Placental cadherin, CDH3, Cadherin-3, P-cadherin, CDHP
Identification and Validation of Th1-Selective Epitopes Derived from Proteins Overexpressed in Breast Cancer Stem Cells., PMID:40432134
Transcriptomic profiling and bioinformatics-driven statistical prioritization of CRC biomarkers: A step toward precision oncology., PMID:40419032
Dual blockage of P-cadherin and c-Met synergistically inhibits the growth of head and neck cancer., PMID:40392501
History of hypoxia exposure aids future cell invasion according to cell type and collagen density., PMID:40327100
Oxidative Stress Regulates CDH3 Expression in Lung Cancer Cells via OGG1-Mediated SP1 Binding., PMID:40227353
Distinct roles of protrusions and collagen deformation in collective invasion of cancer cell types., PMID:40170350
Synergistic potential of CDH3 in targeting CRC metastasis and enhancing immunotherapy., PMID:40155851
Altered structural and transporter-related gene expression patterns in the placenta play a role in fetal demise during Porcine reproductive and respiratory syndrome virus infection., PMID:40119254
Identification and Validation of Biomarkers for Alzheimer's Disease Based on Akt and Wnt Signaling Pathways in Mouse Models., PMID:39992588
Molecular characterization of a rare TP63 variant associated with split-hand/split-foot malformation 4 and incomplete penetrance: disruption of the p63-Dlx signaling pathway., PMID:39910461
CDH3-AS1 antisense RNA enhances P-cadherin translation and acts as a tumor suppressor in melanoma., PMID:39764055
Dynamic changes in the skin transcriptome for the melanin pigmentation in embryonic chickens., PMID:39693959
A TRAILR2/CDH3 bispecific antibody demonstrates selective apoptosis and tumor regression in CDH3-positive pancreatic cancer., PMID:39654063
Classical cadherins evolutionary constraints in primates is associated with their expression in the central nervous system., PMID:39570883
Cadherin adhesion complexes direct cell aggregation in the epithelial transition of Wnt-induced nephron progenitor cells., PMID:39344436
Hsa_circ_0023179 modulated the processes of proliferation, apoptosis, and EMT in non-small cell lung cancer cells via the miR-615-5p/CDH3 axis., PMID:39159001
Associations between multiple neurological biomarkers and distal sensorimotor polyneuropathy: KORA F4/FF4 study., PMID:38872492
Prelude to malignancy: A gene expression signature in normal mammary gland from breast cancer patients suggests pre-tumorous alterations and is associated with adverse outcomes., PMID:38850108
First Transcriptome Analysis of Hepatoblastoma in Brazil: Unraveling the Pivotal Role of Noncoding RNAs and Metabolic Pathways., PMID:38649558
Transcriptomic and proteomic study of cancer cell lines exposed to actinomycin D and nutlin-3a reveals numerous, novel candidates for p53-regulated genes., PMID:38460933
Genome-wide profiling of histone (H3) lysine 4 (K4) tri-methylation (me3) under drought, heat, and combined stresses in switchgrass., PMID:38424499
Comprehensive multiplexed autoantibody profiling of patients with advanced urothelial cancer., PMID:38309723
Identification and validation of prognostic signature genes of bladder cancer by integrating methylation and transcriptomic analysis., PMID:38172584
Downregulated CDH3 is correlated with a better prognosis for LUAD and decreases proliferation and migration of lung cancer cells., PMID:38064156
Alteration of Cadherin 3 Expression and DNA Methylation in Association with Aggressive Renal Cell Carcinoma., PMID:38003666
Photobiomodulation Facilitates Rat Cutaneous Wound Healing by Promoting Epidermal Stem Cells and Hair Follicle Stem Cells Proliferation., PMID:37882982
Hypotrichosis with juvenile macular dystrophy with novel mutations in CDH3 gene., PMID:37850495
Classical cadherins in the testis: how are they regulated?, PMID:37717581
Desmocollin-1 is associated with pro-metastatic phenotype of luminal A breast cancer cells and is modulated by parthenolide., PMID:37620794
Cross-talk of pyroptosis-based subtypes, the development of a risk classifier and immune responses in cervical cancer., PMID:37469224
MicroRNA 133A Regulates Cell Proliferation, Cell Migration, and Apoptosis in Colorectal Cancer by Suppressing CDH3 Expression., PMID:37151391
Regulation of Cdh2 by the AP-1 family transcription factor Junb in TM4 Sertoli cells., PMID:37119763
A proteomics study to explore differential proteins associated with the pathogenesis of ameloblastoma., PMID:37057689
Construction and validation of chemoresistance-associated tumor- infiltrating exhausted-like CD8+ T cell signature in breast cancer: cr-TILCD8TSig., PMID:36949939
Integrated bioinformatics analyses identifying key transcriptomes correlated with prognosis and immune infiltrations in lung squamous cell carcinoma., PMID:36879671
Clinical, genetic, and electron microscopy of hair findings in a patient with CDH3 -related hypotrichosis with juvenile macular dystrophy., PMID:36779776
Artificial neural network identified the significant genes to distinguish Idiopathic pulmonary fibrosis., PMID:36681777
Analysis and identification of potential key genes in hepatic ischemia-reperfusion injury., PMID:36660667
A Cdh3-β-catenin-laminin signaling axis in a subset of breast tumor leader cells control leader cell polarization and directional collective migration., PMID:36626870
Weighted gene co-expression network analysis combined with machine learning validation to identify key hub biomarkers in colorectal cancer., PMID:36576616
The transcription factors Junb and Fosl2 cooperate to regulate Cdh3 expression in 15P-1 Sertoli cells., PMID:36468795
The Role of Radiolabeled Monoclonal Antibodies in Cancer Imaging and ADC Treatment., PMID:36383907
Targeted activation in localized protein environments via deep red photoredox catalysis., PMID:36216892
Hypotrichosis with Juvenile Macular Dystrophy in a Patient with Cadherin 3 (CDH3) Mutation., PMID:35996915
Identification of fusions with potential clinical significance in melanoma., PMID:35871080
Construction and validation of a prognostic risk model for breast cancer based on protein expression., PMID:35787690
P-Cadherin Regulates Intestinal Epithelial Cell Migration and Mucosal Repair, but Is Dispensable for Colitis Associated Colon Cancer., PMID:35563773
CDH3 is associated with poor prognosis by promoting the malignancy and chemoresistance in oral squamous cell carcinoma., PMID:35305877
Expression Profile and Prognostic Values of CDH Family Members in Lung Adenocarcinoma., PMID:35242247
Uncovering potential genes in colorectal cancer based on integrated and DNA methylation analysis in the gene expression omnibus database., PMID:35114976
For research use only. Not for human or drug use.
