Catalog No.
YHD41501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asn341-Ser690
Predicted molecular weight
40.71 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P20742
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Pregnancy zone protein, PZP, CPAMD6, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6
GLIO-Select: Machine Learning-Based Feature Selection and Weighting of Tissue and Serum Proteomic and Metabolomic Data Uncovers Sex Differences in Glioblastoma., PMID:40362575
Proteomic profiles screening identified novel exosomal protein biomarkers for diagnosis of lung cancer., PMID:40229672
Integrated Single-Cell Transcriptome and eQTL Analyses Reveal the Role of PZP in Aging and Chronic Kidney Disease., PMID:40058366
Finding Potential Drug Targets for Pre-Eclampsia Using Mendelian Randomisation and Colocalisation Analysis., PMID:40028697
Pregnancy zone protein, a potential research target in multiple diseases., PMID:39433266
Mesenchymal stromal cells-derived small extracellular vesicles protect against UV-induced photoaging via regulating pregnancy zone protein., PMID:39425900
Proteome- and Transcriptome-Wide Genetic Analysis Identifies Biological Pathways and Candidate Drug Targets for Preeclampsia., PMID:39119725
Host-defence caerin 1.1 and 1.9 peptides suppress glioblastoma U87 and U118 cell proliferation through the modulation of mitochondrial respiration and induce the downregulation of CHI3L1., PMID:38848430
Revisiting the role of pregnancy zone protein (PZP) as a cancer biomarker in the immunotherapy era., PMID:38797856
Mapping dynamic molecular changes in hippocampal subregions after traumatic brain injury through spatial proteomics., PMID:38735925
Guiding the HBO1 complex function through the JADE subunit., PMID:38448574
Screening for Synergistic Reagents With Pazopanib Against Osteosarcoma Using a Compound Library., PMID:38423639
Idiopathic pulmonary fibrosis-specific Bayesian network integrating extracellular vesicle proteome and clinical information., PMID:38225283
Clinical Significance of Pregnancy Zone Protein Expression in Patients With Locally Advanced Gastric Cancer After Curative Resection., PMID:38159976
High-Level Secretion of Pregnancy Zone Protein Is a Novel Biomarker of DNA Damage-Induced Senescence and Promotes Spontaneous Senescence., PMID:37831546
Pregnancy Zone Protein as an Emerging Biomarker for Cardiovascular Risk in Pediatric Chronic Kidney Disease., PMID:37762835
Stromal heterogeneity may explain increased incidence of metaplastic breast cancer in women of African descent., PMID:37709737
Pregnancy Zone Protein Serves as a Prognostic Marker and Favors Immune Infiltration in Lung Adenocarcinoma., PMID:37509617
Genetic Risk Factors Associated With Preeclampsia and Hypertensive Disorders of Pregnancy., PMID:37285119
Whole exome sequencing and rare variant association study to identify genetic modifiers, KLF1 mutations, and a novel double mutation in Thai patients with hemoglobin E/beta-thalassemia., PMID:36939018
BRPF1 bridges H3K4me3 and H3K23ac in human embryonic stem cells and is essential to pluripotency., PMID:36711238
Putative intestinal permeability markers do not correlate with cardiometabolic health and gut microbiota in humans, except for peptides recognized by a widely used zonulin ELISA kit., PMID:36462977
Effect of different adjuvant formulations on the antibody response of horses to porcine zona pellucida proteins., PMID:36327942
TSH-SPP1/TRβ-TSH positive feedback loop mediates fat deposition of hepatocyte: Crosstalk between thyroid and liver., PMID:36300106
Whole genome sequencing identifies candidate genes for familial essential tremor and reveals biological pathways implicated in essential tremor aetiology., PMID:36183486
Overexpression of Pregnancy Zone Protein in Fat Antagonizes Diet-Induced Obesity Under an Intermittent Fasting Regime., PMID:36051914
Predictive value of proteomic markers for advanced rectal cancer with neoadjuvant chemoradiotherapy., PMID:35945555
The Pregnancy Zone Protein (PZP) is significantly downregulated in the placenta of preeclampsia and HELLP syndrome patients., PMID:35843132
TMT-Based Quantitative Proteomics Analysis of Synovial Fluid-Derived Exosomes in Inflammatory Arthritis., PMID:35359923
Renalase and its receptor, PMCA4b, are expressed in the placenta throughout the human gestation., PMID:35322081
Evaluation of Stress Accompanying Immunocontraceptive Vaccination in Donkeys., PMID:35203165
A Novel Diagnostic Biomarker, PZP, for Detecting Colorectal Cancer in Type 2 Diabetes Mellitus Patients Identified by Serum-Based Mass Spectrometry., PMID:34917649
Characterization by Quantitative Serum Proteomics of Immune-Related Prognostic Biomarkers for COVID-19 Symptomatology., PMID:34566994
Hepatokine Pregnancy Zone Protein Governs the Diet-Induced Thermogenesis Through Activating Brown Adipose Tissue., PMID:34514733
Serum exosomal pregnancy zone protein as a promising biomarker in inflammatory bowel disease., PMID:34376139
Molecular basis for bipartite recognition of histone H3 by the PZP domain of PHF14., PMID:34365506
The role of the PZP domain of AF10 in acute leukemia driven by AF10 translocations., PMID:34226546
Structural and biophysical characterization of the nucleosome-binding PZP domain., PMID:33982013
Biomolecular interaction mechanism of an anticancer drug, pazopanib with human serum albumin: a multi-spectroscopic and computational approach., PMID:33870854
Discovery and validation of PZP as a novel serum biomarker for screening lung adenocarcinoma in type 2 diabetes mellitus patients., PMID:33691685
Purification of anti-glycoconjugate monoclonal antibodies using newly developed porous zirconia particles., PMID:33564002
The BRPF1 bromodomain is a molecular reader of di-acetyllysine., PMID:33554132
Hypermethylation of the PZP gene is associated with hepatocellular carcinoma cell proliferation, invasion and migration., PMID:33471436
Pregnancy Zone Protein (PZP) is significantly upregulated in the decidua of recurrent and spontaneous miscarriage and negatively correlated to Glycodelin A (GdA)., PMID:33388716
Prognostic Significance of Pregnancy Zone Protein and Its Correlation with Immune Infiltrates in Hepatocellular Carcinoma., PMID:33116846
Genetic ablation of pregnancy zone protein promotes breast cancer progression by activating TGF-β/SMAD signaling., PMID:33057846
Novel poricoic acids attenuate renal fibrosis through regulating redox signalling and aryl hydrocarbon receptor activation., PMID:32920287
Spliceosome protein EFTUD2 is upregulated in the trophoblast of spontaneous miscarriage and hydatidiform mole., PMID:32447180
Efficacy and safety of native and recombinant zona pellucida immunocontraceptive vaccines in donkeys., PMID:32417608
For research use only. Not for human or drug use.
