Catalog No.
YHD31701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg138-Leu443
Predicted molecular weight
37.65 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P19013
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CYK4, Keratin-4, Type-II keratin Kb4, Cytokeratin-4, KRT4, K4, Keratin, type II cytoskeletal 4, CK-4
Mass spectrometric detection of keratins in tear fluid., PMID:39761842
Integrated singlecell and bulk RNA-seq analysis identifies a prognostic signature related to inflammation in colorectal cancer., PMID:39757274
Brainstem transcriptomic changes in male Wistar rats after acute stress, comparing the use of duplex specific nuclease (DSN)., PMID:39300279
A computational study of gene expression patterns in head and neck squamous cell carcinoma using TCGA data., PMID:39140365
Malignant transformation of white sponge nevus: a case report of a novel keratin 4 mutation., PMID:38773401
The RNA m6A writer RBM15 contributes to the progression of esophageal squamous cell carcinoma by regulating miR-3605-5p/KRT4 pathway., PMID:38312624
BNIPL is a promising biomarker of laryngeal cancer: novel insights from bioinformatics analysis and experimental validation., PMID:38302910
In silico prediction and a systematic toxicology-based in vivo investigation uncovering the mechanism of aquatic toxicity caused by beta-lactam antibiotics., PMID:38065262
Tryptanthrin inhibits tumor angiogenesis via Notch/Dll4 signaling pathway in zebrafish., PMID:37969390
Molecular Characterization of Esophageal Squamous Cell Carcinoma Using Quantitative Proteomics., PMID:37444412
Prognostic survival biomarkers of tumor-fused dendritic cell vaccine therapy in patients with newly diagnosed glioblastoma., PMID:37382632
Super Enhancer-Associated Circular RNA-CircKrt4 Regulates Hypoxic Pulmonary Artery Endothelial Cell Dysfunction in Mice., PMID:37139839
Identification of immune-related genes contributing to head and neck squamous cell carcinoma development using weighted gene co-expression network analysis., PMID:37092360
Salivary annexin A1: A candidate biomarker for periodontitis., PMID:36935103
Efficient knock-in method enabling lineage tracing in zebrafish., PMID:36878640
Splice site m6A methylation prevents binding of DGCR8 to suppress KRT4 pre-mRNA splicing in oral squamous cell carcinoma., PMID:36811004
The Annotation of Zebrafish Enhancer Trap Lines Generated with PB Transposon., PMID:35735619
Negative regulation of miR-1288-3p/KRT4 axis through a circular RNA in oral cancer., PMID:35707935
Barrett's Metaplasia Progression towards Esophageal Adenocarcinoma: An Attempt to Select a Panel of Molecular Sensors and to Reflect Clinical Alterations by Experimental Models., PMID:35328735
In Silico Study to Predict the Structural and Functional Consequences of SNPs on Biomarkers of Ovarian Cancer (OC) and BPA Exposure-Associated OC., PMID:35163645
Identification of potential biomarkers and available drugs for oral squamous cell carcinoma., PMID:35116246
Genome-wide identification, characterization, and expression analysis of keratin genes (KRTs) family in yak (Bos grunniens)., PMID:35085710
Proteomic profiling of saliva reveals association of complement system with primary Sjögren's syndrome., PMID:34516718
Identification of Potential Bisphenol A (BPA) Exposure Biomarkers in Ovarian Cancer., PMID:34062972
Whole-exome sequencing reveals potential germline and somatic mutations in 60 malignant ovarian germ cell tumors†., PMID:33739378
Down-Regulation of Long Non-Coding RNA TINCR Induces Cell Dedifferentiation and Predicts Progression in Oral Squamous Cell Carcinoma., PMID:33732637
An Irf6-Esrp1/2 regulatory axis controls midface morphogenesis in vertebrates., PMID:33234718
[A boy with white sponge naevus of the buccal mucosa]., PMID:32940983
Identification of Hub Genes Associated With Development of Head and Neck Squamous Cell Carcinoma by Integrated Bioinformatics Analysis., PMID:32528874
Urethral luminal epithelia are castration-insensitive cells of the proximal prostate., PMID:32497356
CD24 and CK4 are upregulated by SIM2, and are predictive biomarkers for chemoradiotherapy and surgery in esophageal cancer., PMID:32124945
Autophagy-based unconventional secretion of HMGB1 by keratinocytes plays a pivotal role in psoriatic skin inflammation., PMID:32019420
The Overexpression of Tβ4 in the Hair Follicle Tissue of Alpas Cashmere Goats Increases Cashmere Yield and Promotes Hair Follicle Development., PMID:31906185
Transcriptomic Analyses of Inner Ear Sensory Epithelia in Zebrafish., PMID:31883312
Toll-like receptor 4-mediated respiratory syncytial virus disease and lung transcriptomics in differentially susceptible inbred mouse strains., PMID:31736414
Novel diterpenoid-type activators of the Keap1/Nrf2/ARE signaling pathway and their regulation of redox homeostasis., PMID:31167117
MEIS1 knockdown may promote differentiation of esophageal squamous carcinoma cell line KYSE-30., PMID:31090196
Keratin 4 regulates the development of human white sponge nevus., PMID:29738605
Clinical features and molecular genetic analysis in a Turkish family with oral white sponge nevus., PMID:29476668
The analysis of human conjunctival epithelium proteome in ocular surface diseases using impression cytology and 2D-DIGE., PMID:28336260
The alcohol-sensitive period during early octavolateral organ development in zebrafish (Danio rerio)., PMID:28105691
Profound loss of esophageal tissue differentiation in patients with eosinophilic esophagitis., PMID:28104354
Climbazole boosts activity of retinoids in skin., PMID:28103388
A unique lineage gives rise to the meibomian gland., PMID:26957900
A Zebrafish Model for Studies on Esophageal Epithelial Biology., PMID:26630178
Keratin 13 mutations associated with oral white sponge nevus in two Chinese families., PMID:25606422
Structure of KRT4 binding domain of Srr-1 from Streptococcus agalactiae reveals a novel β-sheet complementation., PMID:25603146
Early dental epithelial transcription factors distinguish ameloblastoma from keratocystic odontogenic tumor., PMID:25398365
Large-scale proteomics differentiates cholesteatoma from surrounding tissues and identifies novel proteins related to the pathogenesis., PMID:25093596
Melanoma differentiation-associated gene-7/interleukin-24 as a potential prognostic biomarker and second primary malignancy indicator in head and neck squamous cell carcinoma patients., PMID:25091574