Catalog No.
YHD31001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Ser181
Predicted molecular weight
47.42 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P18847
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ATF3, Cyclic AMP-dependent transcription factor ATF-3, cAMP-dependent transcription factor ATF-3, Activating transcription factor 3
Targeting to High-Density Lipoprotein Cholesterol: New Insights for Inflammatory Bowel Disease Treatment., PMID:40484317
Sigma-1R-Pom121 axis preserves nuclear transport and integrity in poly-PR-induced C9orf72 ALS., PMID:40480424
The role of ATF3 in the crosstalk between cellular stress response and ferroptosis in tumors., PMID:40473084
Relationship Between Activating Transcription Factor 3 and Forkhead Box Protein A2 in Spinal Cord Injury and the Underlying Mechanism., PMID:40464835
STAT3 Facilitates Super Enhancer Formation to Promote Fibroblast-To-Myofibroblast Differentiation by the Analysis of ATAC-Seq, RNA-Seq and ChIP-Seq., PMID:40464702
Identify the co-expressed genes of hypertensive nephropathy and diabetic nephropathy., PMID:40461634
Activating Transcription Factor 3 (ATF3) Regulates Cellular Senescence and Osteoclastogenesis via STAT3/ERK and p65/AP-1 Pathways in Human Periodontal Ligament Cells., PMID:40430099
Sequential activation of transcription factors promotes liver regeneration through specific and developmental enhancers., PMID:40409273
Correlations between ATF3 polymorphisms and ischemic stroke in Dali, Yunnan Province, as determined by a case-control study., PMID:40399867
Repeat-element RNAs integrate a neuronal growth circuit., PMID:40381624
Atf3 + senescent chondrocytes mediate meniscus degeneration in aging., PMID:40375324
Methylprednisolone Protects Human Pancreatic Beta Cells From Inflammation-induced Damage., PMID:40371054
Pain in Fibrous Dysplasia: Identifying Nociceptive Mechanisms in a Preclinical Model., PMID:40367355
Lactobacillus rhamnosus GG Supernatant Improves GLP-1 Secretion Through Attenuating L Cell Lipotoxicity and Modulating Gut Microbiota in Obesity., PMID:40366615
Evaluation of anti-leukemic activity and underlying mechanisms of the novel GSPT1 degrader AB138 in acute myeloid leukemia., PMID:40366532
Exosomal transfer of pro-pyroptotic miR-216a-5p exacerbates anthracycline cardiotoxicity through breast cancer-heart pathological crosstalk., PMID:40360476
DA.Vra1-congenic rats display increased gene expression and Schwann cell apoptosis but unaffected nerve regeneration compared to parental DA rats after sciatic nerve injury and repair., PMID:40356597
Pretreatment with dimethyl fumarate prevents chronic pain and its comorbidities via Nrf2 pathway in a rat model of neuropathic pain., PMID:40349732
Silencing of activating transcription factor 3 alleviates oxidative stress and inflammation and improves cognitive dysfunction in vascular dementia rats by repressing ferroptosis., PMID:40347885
Rational development of gemcitabine-based nanoplatform for targeting SERPINB9/Granzyme B axis to overcome chemo-immune-resistance., PMID:40325025
ATF3 restoration as a potential strategy in managing ulcerative colitis: Implications from Sishen pill research., PMID:40318535
Metformin regulates ferroptosis in Skin cutaneous melanoma via ATF3/NRF2 axis., PMID:40318300
The oncoprotein DEK controls growth-regulated gene expression by enhancing the DNA-binding activity of basic leucine zipper transcription factors., PMID:40318137
Copy Number Gains of VPS72 Drive De Novo Lipogenesis and Hepatocarcinogenesis via ATF3/mTORC1/SREBP1 Axis., PMID:40305746
Analgesic and neuroprotective effect of a lipid transfer protein isolated from Morinda citrifolia L. (noni) seeds on oxaliplatin-induced peripheral sensory neuropathy in mice., PMID:40304749
Functional Specificity of Astrocyte Subtypes in Alzheimer's Disease: Decoding Disease Mechanisms Through Network-based Analysis of Integrated Single-Nuclei Multi-Omic Data., PMID:40301248
Tables Turned─Structural Mechanisms of Target-Induced miRNA Destabilization., PMID:40300196
Expression of Galectin 3 and Activating Transcription Factor 3 in Nigral Dopaminergic Neurons of 6-Hydroxydopamine Induced Parkinsonian Rat Model., PMID:40295017
Specificity protein 1 (SP1) plays an essential role in early bovine embryo development., PMID:40286422
Transcriptional landscape and chromatin accessibility reveal key regulators for liver regenerative initiation and organoid formation., PMID:40286271
Closing the gap: Nonviral TFAMoplex transfection boosted by bZIP domains compared to AAV-mediated transduction., PMID:40276698
Salsalate improves the anti-tumor efficacy of lenvatinib in MASH-driven hepatocellular carcinoma., PMID:40276482
Knockdown of ATF3 Alleviates Ischemic Stroke and Inhibits Ferroptosis via Activating the Keap1/Nrf2/HO- 1 Pathway., PMID:40272768
The BATF2-ATF3 axis exacerbates intervertebral disc degeneration via inducing mitochondrial dysfunction., PMID:40267724
A novel finding relates to the involvement of ATF3/DOCK8 in Alzheimer's disease pathogenesis., PMID:40267290
Lactoferrin-derived peptide PXL01 impacts nerve regeneration after sciatic nerve reconstruction in healthy and diabetic rats., PMID:40260416
Protective effects of albiflorin on acetaminophen-induced hepatotoxicity: Regulation of blood-biliary barrier integrity by ATF3., PMID:40250002
Integrator loss leads to dsRNA formation that triggers the integrated stress response., PMID:40233738
ATF3 Within the Interferon Signaling Pathway: A Potential Biomarker for Predicting Pathological Response to Neoadjuvant Chemoimmunotherapy., PMID:40223203
Repurposing of activating transcription factor 3 (ATF3) activator molecules with potential wound-healing effects., PMID:40220516
Suppression of cisplatin induced ATF3 expression and apoptosis by BK polyomavirus and its encoded microRNA in bladder cancer cells., PMID:40215645
Transcriptome Analysis Reveals Anti-inflammatory, Antiapoptotic, and Milk Synthesis-Promoting Effects of Lithium Chloride in Bovine Mammary Epithelial Cells., PMID:40214951
Thiotaurine inhibits melanoma progression by enhancing Ca2+ overload-induced cellular apoptosis., PMID:40189970
Transcriptomic analysis of digitoxin: Synergy with doxorubicin in HER2-overexpressing MDA-MB-453 breast cancer cells., PMID:40188858
Atf3 controls transitioning in female mitochondrial cardiomyopathy as identified by spatial and single-cell transcriptomics., PMID:40184463
Inhibition of p16 and NF-κB Oncogenic Activity in Human Papillomavirus-Infected Cervical Cancer Cells: A New Role for Activating Transcription Factor-3., PMID:40165810
Estradiol activates the CaMKKβ/AMPK pathway to enhance neurite outgrowth in cultured adult sensory neurons., PMID:40164320
Activating transcription factor 3 regulates hepatic apolipoprotein A4 upon metabolic stress., PMID:40158856
Vitamin D3 and its active form calcitriol suppress erythroleukemia through upregulation of CHAC1 and downregulation of NOTCH1., PMID:40146328
Molecular basis for human respiratory syncytial virus transcriptional regulator NS1 interactions with MED25., PMID:40128225
For research use only. Not for human or drug use.
