Catalog No.
YHD23501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Phe232-Ile382
Predicted molecular weight
18.72 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P17302
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
GJAL, Connexin-43, GJA1, Cx43, Gap junction 43 kDa heart protein, Gap junction alpha-1 protein
Antidepressant effects of fluoxetine: upregulation of connexin 36 and 43 in the hippocampus, prefrontal cortex, and amygdala., PMID:40498164
Mechanism of myocardial damage induced by doxorubicin via calumenin-regulated mitochondrial dynamics and the calcium-Cx43 pathway., PMID:40496395
Molecular dynamics simulation of GJC2 mutants reveal pathogenic mechanisms of PMLD1 and SPG44., PMID:40493033
A potential therapeutic target at Connexin 43 serine phosphorylation against ischaemia/reperfusion arrhythmia., PMID:40490933
Selenium alleviates cadmium-induced Golgi stress via HSPB7/GM130/CX-43 axis in the heart of sheep., PMID:40490057
Insulin and Metformin are Associated With Reduced Risk of Amyotrophic Lateral Sclerosis., PMID:40486953
Glyoxal is a superior fixative to formaldehyde in promoting antigenicity and structural integrity in murine cardiac tissues., PMID:40485774
Electroacupuncture alleviates corpus callosum injury in rats with ischemic stroke by inhibiting excessive activation of astrocytes and overexpression of connexin 43., PMID:40485117
Inhibition of GRK4 reduces arrhythmia susceptibility and alleviates connexin43 dysregulation after myocardial infarction., PMID:40484036
Cytoplasmic mutant RBM20 causes arrhythmogenicity in murine atria., PMID:40480405
Mapping satellite glial cell heterogeneity reveals distinct spatial organization and signifies functional diversity in the dorsal root ganglion., PMID:40475507
Protective effects of artesunate on the neurovascular unit by regulating PDGFRβ signaling in experimental cerebral malaria., PMID:40473225
Modified Citrus Pectin Alleviates Diabetic Kidney Disease by Suppressing Pyroptosis in Renal Tubular Epithelial Cells via the Cx43-ERK1/2 Signaling Pathway., PMID:40460282
Electrophysiological Functions of Macrophages are Involved in Atrial Fibrillation., PMID:40455553
Adverse effects of a realistic concentration of human exposure to microplastics on markers of placental barrier permeability in pregnant rats., PMID:40445558
Vanari Gutika supplementation enhances testicular function by modulating spermatogenesis, oxidative balance, and blood-testis barrier integrity., PMID:40444477
Cx43 mediates cross-talk of tumor cells and macrophage via cGAS-STING signaling., PMID:40437141
The role of connexin-43 in modeling arrhythmogenic diseases with induced pluripotent stem cell-derived cardiomyocytes., PMID:40436246
Matrix viscoelasticity drives cell cluster formation to counteract cellular senescence., PMID:40432619
Gap Junctional Interaction of Endothelial Progenitor Cells (EPC) with Endothelial Cells Induces Angiogenic Network Formation In Vitro., PMID:40429968
Bibliometric analysis and visualization of Connexin 43 in the field of solid tumor research(2000-2024)., PMID:40416989
The expression of connexin 36 and 43 in animal models of trait and state anxiety., PMID:40389052
Impact of the environmental endocrine disruptor flutamide on cryptorchidism: Molecular mechanisms involving connexin-43 and p38-MAPK signaling., PMID:40381864
Cytoplasmic connexin43-microtubule interactions promote glioblastoma stem-like cell maintenance and tumorigenicity., PMID:40379630
Histone Deacetylase 6 Controls Atrial Fibrosis and Remodeling in Postinfarction Mice Through the Modulation of Wnt3a/GSK-3β Signaling., PMID:40377174
Lactobacillus Restructures the Micro/Mycobiome to Combat Inflammation-Mediated Right Ventricular Dysfunction in Pulmonary Arterial Hypertension., PMID:40376801
Celastrol Ameliorates Vincristine-induced Neuropathic Pain by Inhibiting Spinal Astrocyte Hyperactivation-mediated Inflammation, Oxidative Stress, and Apoptosis., PMID:40375704
Melatonin reverses bisphenol A-induced toxicity in granulosa cells: Restoration of FSHR and connexin 43 expression., PMID:40368516
14-3-3 proteins: Regulators of cardiac excitation-contraction coupling and stress responses., PMID:40349303
The effects of green light-emitting diode irradiation and inducer factors on the differentiation of human adipose tissue-derived mesenchymal cells into myocardial-like cells., PMID:40347405
Electrohydrodynamically-printed Serpentine Fiber Scaffolds with Enhanced Conductivity and Elasticity for Post-Myocardial Infarction Repair., PMID:40339971
Research progress of connexin 43 mediated gap junction communication regulating bone metabolism in glucocorticoid-induced osteonecrosis of the femoral head., PMID:40339781
Cardiac electrical abnormalities in a mouse model of left ventricular non-compaction cardiomyopathy., PMID:40334239
Bone marrow mesenchymal stem cells transport connexin43 via tunneling nanotubes to alleviate isopreterenol-induced myocardial hypertrophy., PMID:40329337
Size-Dependent Effects of Phyllanthus niruri Nanoemulsions on Blood-Testis Barrier Integrity and Cellular Responses in TM4 Sertoli Cells., PMID:40323764
Muscle-specific isoforms of FXR1 are necessary for miR-1-mediated repression of connexin 43 and are downregulated in pediatric dilated cardiomyopathy., PMID:40323739
Connexin-43 remodelling and arrhythmias: hemichannels as key drivers of cardiac dysfunction., PMID:40320914
Adenosine transmission from hypothalamic tanycytes to AGRP/NPY neurons regulates energy homeostasis., PMID:40316705
Endometriotic Follicular Fluid Affects Granulosa Cells' Morphology and Increases Duplication Rate and Connexin-43 Expression., PMID:40305294
The Role of Fibroblast Growth Factor Receptor 2 as A Prognostic Biomarker in Colorectal Adenocarcinoma., PMID:40302086
Augmented hippocampal up-regulation of immune modulators following a peripheral immune challenge in a hemizygous mouse model of the 15q13.3 microdeletion., PMID:40300236
Connexin-43 Protein Expression Pattern Analysis in Myocardial Infarction Tissues., PMID:40295004
Cx45 regulation by kinases and impact of expression in heart failure., PMID:40280467
GSNO induced mitochondrial Cx43 nitrosylation in cardiomyocyte differentiation from mouse ES cells in vitro., PMID:40280246
Myocardial expression of connexin 43 in cats with hypertrophic and restrictive cardiomyopathy phenotype., PMID:40276190
Distinct intracellular spatiotemporal expression of Calmodulin genes underlies functional diversity of CaM-dependent signaling in cardiac myocytes., PMID:40273382
The impact of Connexin 43 deficiency on the cell shape and cytoskeleton of murine Sertoli cells: A house with ramshackle walls?, PMID:40273151
Glial connexins in glaucoma., PMID:40270762
Limbal explant cultures on amniotic membrane: The effects of passaging the explants on cell phenotype., PMID:40250725
Downregulation of EB1 impedes Cx43 localization and cardiac conduction after hypothermic ischemia-reperfusion in rats., PMID:40247841
For research use only. Not for human or drug use.
