Catalog No.
YHD23101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu140-Thr250
Predicted molecular weight
38.74 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P17213
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
BPI, Bactericidal permeability-increasing protein, CAP 57
Host-microbiota interactions in the infant gut revealed by daily faecal sample time series., PMID:40207273
The dual functions of the GTPase BipA in ribosome assembly and surface structure biogenesis in Salmonella enterica serovar Typhimurium., PMID:40203049
Chimeric hBPI23-Fcγ protein shows bactericidal activity against drug-resistant Gram-negative bacteria and protects mice from lethal challenge., PMID:40152989
Bactericidal/Permeability-Increasing Protein (BPI), a Novel Antimicrobial Molecule in Human Breast Milk with Immune Potential., PMID:39858883
Inflammation and response to bacterial infection as potential drivers of equine odontoclastic tooth resorption and hypercementosis: A proteomics insight., PMID:39777419
CLCA1 and BPIFB1 are potential novel biomarkers for asthma: an iTRAQ analysis., PMID:39552876
The vacuolar anti-Pseudomonal activity of neutrophil primary granule peptidyl-arginine deiminase enzymes., PMID:39493757
A novel LPS binding /bactericidal permeability-increasing protein (LBP/BPI) from the scallop Argopecten purpuratus plays an essential role in host resistance to Vibrio infection., PMID:39471964
The performance of a combination of heparin-binding protein with other biomarkers for sepsis diagnosis: an observational cohort study., PMID:39080540
Plasma levels of bactericidal/permeability-increasing protein correlate with systemic inflammation in acute coronary syndrome., PMID:38933945
Bactericidal Permeability-Increasing Protein (BPI) Inhibits Mycobacterium tuberculosis Growth., PMID:38672491
Serum proteomic profiling of patients with compensated advanced chronic liver disease with and without clinically significant portal hypertension., PMID:38603681
[Acute and chronic rhinosinusitis age characteristics]., PMID:38506028
Subversion of a family of antimicrobial proteins by Salmonella enterica., PMID:38505286
Bactericidal/permeability-increasing protein instructs dendritic cells to elicit Th22 cell response., PMID:38457343
Genes and Pathways Underpinning Klinefelter Syndrome at Bulk and Single-Cell Levels., PMID:38374521
BPI23-Fcγ alleviates lethal multi-drug-resistant Acinetobacter baumannii infection by enhancing bactericidal activity and orchestrating neutrophil function., PMID:37838150
Scorpionfish BPI is highly active against multiple drug-resistant Pseudomonas aeruginosa isolates from people with cystic fibrosis., PMID:37461324
Decoding the fibromelanosis locus complex chromosomal rearrangement of black-bone chicken: genetic differentiation, selective sweeps and protein-coding changes in Kadaknath chicken., PMID:37424723
Identification and Functional Analysis of ToBPI1/LBP and ToBPI2/LBP in Anti-Bacterial Infection of Trachinotus ovatus., PMID:37107584
Spectrum of ANCA-specificities in eosinophilic granulomatosis with polyangiitis. A retrospective multicentre study., PMID:37073637
Lipocalin-2 and neutrophil activation in pancreatic cancer cachexia., PMID:37006254
Resistance of Argopecten purpuratus scallop larvae to vibriosis is associated with the front-loading of immune genes and enhanced antimicrobial response., PMID:36936911
Salmonella Typhimurium PgtE is an essential arsenal to defend against the host resident antimicrobial peptides., PMID:36931126
Salivary bactericidal/permeability-increasing protein: A novel inflammatory marker associated with periodontitis., PMID:36805805
LL-37 Triggers Antimicrobial Activity in Human Platelets., PMID:36769137
Molecular Evolution of the Bactericidal/Permeability-Increasing Protein (BPIFA1) Regulating the Innate Immune Responses in Mammals., PMID:36672756
Characterising the autoantibody repertoire in systemic sclerosis following myeloablative haematopoietic stem cell transplantation., PMID:36653124
Bactericidal/Permeability-Increasing Protein Downregulates the Inflammatory Response in In Vivo Models of Arthritis., PMID:36361854
Bactericidal permeability-increasing protein/LPS-binding protein (BPI/LBP) enhances resistance of golden pompano Trachinotus ovatus against bacterial infection., PMID:36347416
Identification and functional characterization of bactericidal permeability/increasing protein (BPI) from frog Nanorana yunnanensis (Paa yunnanensis)., PMID:36028172
Distinct Uptake Routes Participate in Silver Nanoparticle Engulfment by Earthworm and Human Immune Cells., PMID:36014683
Plasma Membrane-Associated Proteins Identified in Arabidopsis Wild Type, lbr2-2 and bak1-4 Mutants Treated with LPSs from Pseudomonas syringae and Xanthomonas campestris., PMID:35736313
The Activity of Antimicrobial Peptides in Pediatric Celiac Disease., PMID:35733815
β-arrestin interacts with TRAF6 to negatively regulate the NF-κB pathway in triangle sail mussel Hyriopsis cumingii., PMID:35705131
Untargeted Metabolomics Profiling of Arabidopsis WT, lbr-2-2 and bak1-4 Mutants Following Treatment with Two LPS Chemotypes., PMID:35629883
Human transcriptomic response to periprosthetic joint infection., PMID:35306116
A Polymorphism of Bactericidal/Permeability-Increasing Protein Affects Its Neutralization Efficiency towards Lipopolysaccharide., PMID:35163248
Effect of silver nanoparticles on gene transcription of land snail Helix aspersa., PMID:35136168
Retraction: Bactericidal/Permeability-Increasing Protein Improves Cognitive Impairment in Diabetic Mice via Blockade of the LPS-LBP-TLR4 Signaling Pathway., PMID:35027892
C3d Elicits Neutrophil Degranulation and Decreases Endothelial Cell Migration, with Implications for Patients with Alpha-1 Antitrypsin Deficiency., PMID:34944741
BPI overexpression suppresses Treg differentiation and induces exosome-mediated inflammation in systemic lupus erythematosus., PMID:34815797
Level and avidity of antineutrophil cytoplasmic antibodies specific to lactoferrin are useful biomarkers in systemic lupus erythematosus., PMID:34618258
Occurrence and Antigenic Specificity of Perinuclear Anti-Neutrophil Cytoplasmic Antibodies (P-ANCA) in Systemic Autoimmune Diseases., PMID:34440897
Positive correlations between plasma BPI level and MPO-DNA and S100A8/A9 in myocardial infarction., PMID:34387532
Differential Enhancement of Neutrophil Phagocytosis by Anti-Bactericidal/Permeability-Increasing Protein Antibodies., PMID:34272233
Killing three birds with one BPI: Bactericidal, opsonic, and anti-inflammatory functions., PMID:34142075
Identification of leaky gut-related markers as indicators of metabolic health in Dutch adults: The Nutrition Questionnaires plus (NQplus) study., PMID:34086828
Molecular characterization and functional analysis of the bactericidal permeability-increasing protein/LPS-binding protein (BPI/LBP) from roughskin sculpin (Trachidermus fasciatus)., PMID:34000320
Maternal supplementation with cobalt sources, folic acid, and rumen-protected methionine and its effects on molecular and functional correlates of the immune system in neonatal Holstein calves., PMID:33985772
For research use only. Not for human or drug use.
