Catalog No.
YHD27201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly135-Thr277
Predicted molecular weight
18.61 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P17936
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
IBP-3, Insulin-like growth factor-binding protein 3, IGF-binding protein 3, IBP3, IGFBP-3, IGFBP3
IGFBP3 modulation of tumor pathogenesis and cell signaling pathways (Review)., PMID:40503041
Impact of IGFBP-3 A-202C genetic variant on breast cancer susceptibility and serum biomarkers (IGFBP-3 and IGF-1) in Palestinian women., PMID:40493660
Chromatin architecture protein HMGA2 promotes glioma malignancy via novel mechanism of IGFBP3 transcription inhibition., PMID:40450974
Controllable nickel ions release from deferoxamine mesylate-triggered nickel-iron layered double hydroxide for eliciting apoptotic cell death in prostate cancer., PMID:40448082
Xanthosomes loaded with recombinant TMEM219 for targeting IGFBP-3: A novel approach for targeted drug delivery to ameliorate liver fibrosis., PMID:40447257
Correlation of Body Mass Index with Serum Osteocalcin and Insulin-Like Growth Factor Binding Protein-3 in the Assessment of Pubertal Growth Spurt - A Comparative Study., PMID:40439207
Aerobic exercise alleviates chronic allergic airway inflammation by regulating the circMETTL9/EIF4A3/IGFBP3 axis., PMID:40436287
DBI as a Novel Immunotherapeutic Candidate in Colorectal Cancer: Dissecting Genetic Risk and the Immune Landscape via GWAS, eQTL, and pQTL., PMID:40426943
Potential diagnostic marker gene set for non-alcoholic steatohepatitis associated hepatocellular carcinoma with lymphocyte infiltration., PMID:40386252
New Gene Targets for Diagnosis and Therapy of Diabetic Retinopathy., PMID:40377287
The influence of gender-affirming hormone therapy on serum concentrations of hormone-binding proteins., PMID:40377124
Humulus japonicus Enhances Bone Growth and Microarchitecture in Rats: Potential Involvement of IGF-1 Signaling., PMID:40372960
TMEM219 signaling promotes intestinal stem cell death and exacerbates colitis., PMID:40371646
Association of serum insulin-like growth factor-1 and adrenocorticotropic hormone therapeutic response in patients with infantile epileptic spasms syndrome., PMID:40371354
IGFBP3 enhances adipose-derived stem cell function in soft tissue injury repair via ITGB1 and ERK pathway activation., PMID:40369223
Soluble alpha klotho-impact of biological variables and reference intervals for adults., PMID:40338072
MRI-Based Evaluation of Pituitary Size and Volume in Children with Idiopathic Growth Hormone Deficiency., PMID:40326894
Predictive Effect of IGFBP-3 on Low-Dose Tamoxifen Efficacy in Noninvasive Breast Cancer in the Phase III Tam-01 Trial., PMID:40293268
Early warning value of multiple serum indicators combined with ultrasound detection in girls with central precocious puberty., PMID:40260284
Research progress on ADAM28 in malignant tumors., PMID:40252142
X-ray-Sensitive Selenium Nanoparticles Enhance Esophageal Squamous Cell Carcinoma Radiotherapy through Activating P53/IGFBP3 Pathway by Regulating GPX2., PMID:40241246
Markers for the angiogenic potential of fat grafts., PMID:40232500
Feasibility, safety, and efficacy of high-dose intermittent theta burst stimulation in children with autism spectrum disorder: study protocol for a pilot randomized sham-controlled trial., PMID:40230821
Changes in the expression pattern of genes affecting the growth and development of mammary tissue in pregnant Saanen goats in response to dietary fats., PMID:40215566
Role of IGFBP-3 in Human Diseases Relying on Different Cell Signaling Pathways., PMID:40213590
Associations of circulating insulin-like growth factor-1 and insulin-like growth factor binding protein-3 with the expression of stem cell markers in benign breast tissue., PMID:40197284
Expression of Salivary and Serum IGF-1 and IGFBP-3 in Individuals With Diabetes and Oral Cancer., PMID:40182453
Insulin-like growth factor binding protein-3 (IGFBP-3): a biomarker of coronary artery disease induced myocardial ischaemia., PMID:40177504
Role of Quercetin in Modulating Inflammation and Epigenetic Regulation of Staphylococcus aureus-Induced Bovine Mastitis., PMID:40168353
PromarkerD Versus Standard of Care Biochemical Measures for Assessing Future Renal Function Decline in Type 2 Diabetes., PMID:40150005
Associations between Serum Insulin-Like Growth Factor-Related Molecules and Colorectal Cancer Risk by Tumor Location: A Nested Case-Control Study., PMID:40132573
Pharmacodynamics, pharmacokinetics, and toxicology of Fc-growth hormone fusion protein in macaques., PMID:40120208
Aregs-IGFBP3-mediated SMC-like cells apoptosis impairs beige adipocytes formation in aged mice., PMID:40118146
Targeted proteomics of serum IGF-I, -II, IGFBP-2, -3, -4, -5, -6 and ALS., PMID:40116411
TBK1 is a signaling hub in coordinating stress-adaptive mechanisms in head and neck cancer progression., PMID:40114316
IGF1 Signaling Regulates Neuropeptide Expression in Hypothalamic Neurons Under Physiological and Pathological Conditions., PMID:40105689
Circ_0044362 Facilitates the Progression of Epithelial Ovarian Cancer via Enhancing HOXB4 Transcription to Activate the RUNX1/IGFBP3 Axis., PMID:40099691
Antibodies against the receptor for insulin-like growth factor 1 (IGF-1RAb), insulin-like growth factor 1 (IGF-1), and insulin-like growth factor binding protein 3 (IGFBP-3) in the serum of patients with Graves' and Basedow's disease with and without orbitopathy., PMID:40071798
Exploring the Plasma Proteome: Identifying Hub Proteins linking Aging, Homeostasis, and Organ Function., PMID:40027189
The mechanism of high mobility group box-1 in the proliferation and macrophage polarization in esophageal squamous cell carcinoma cells., PMID:40022250
Efficacy of Naringenin against aging and degeneration of nucleus pulposus cells through IGFBP3 inhibition., PMID:40000729
Absence of genetic association between insulin-like growth factors and esophageal cancer., PMID:39969361
The Effects of a Novel Astragalus-Based Extract (Keyfobell Powder (KFB)) on Longitudinal Bone Growth via IGF-1 Upregulation: A Potential Growth Hormone Alternative., PMID:39940274
Neutrophil-to-lymphocyte ratio is associated with accelerometer-measured physical activity levels in breast cancer survivors., PMID:39939471
Comparison of growth hormone therapy response according to the presence of growth hormone deficiency in children born small for gestational age with short stature in Korea: a retrospective cohort study., PMID:39893395
HDAC3 and Snail2 complex promotes melanoma metastasis by epigenetic repression of IGFBP3., PMID:39864688
Exploring the mechanism of rosmarinic acid in the treatment of lung adenocarcinoma based on bioinformatics methods and experimental validation., PMID:39812944
Insulin and Insulin-like Growth Factor and Risk of Postmenopausal Estrogen Receptor-Positive Breast Cancer: A Case-Cohort Analysis., PMID:39808164
Identification of IGFBP3 and LGALS1 as potential secreted biomarkers for clear cell renal cell carcinoma based on bioinformatics analysis and machine learning., PMID:39807607
Effects of recombinant human growth hormone injection combined with Anastrozole on height and growth rate of adolescent idiopathic short stature and evaluation of adverse reactions., PMID:39799442
For research use only. Not for human or drug use.
