Catalog No.
YHC96201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala45-Leu313
Predicted molecular weight
32.45 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P13051
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
DGU, Uracil-DNA glycosylase, UNG15, UDG, UNG, UNG1
Acid ceramidase inhibition enhances BCL-2 targeting in venetoclax-resistant acute myeloid leukemia via a cytotoxic integrated stress response., PMID:40501740
Herpes simplex virus 1 evades APOBEC1-mediated immunity via its uracil-DNA glycosylase in mice., PMID:40461648
Bacteroides sphingolipids promote anti-inflammatory responses through the mevalonate pathway., PMID:40449488
Effectiveness of resveratrol in inducing adeno-associated virus as a potential definitive therapy for SCN5A mutation in Brugada syndrome: a narrative review., PMID:40338408
Microfluidic Optimization of PEI-Lipid Hybrid Nanoparticles for Efficient DNA Delivery and Transgene Expression., PMID:40284449
sST2 is a key outcome biomarker in COVID-19: insights from discovery randomized trial., PMID:40274842
Transport of phenoxyacetic acid herbicides by PIN-FORMED auxin transporters., PMID:40263580
Liver-targeted allergen immunotherapy rapidly and safely induces antigen-specific tolerance to treat allergic airway disease in mice., PMID:40238914
N6-methyladenosine in DNA promotes genome stability., PMID:40193195
Isocitrate dehydrogenase-mutant astrocytoma in persons aged 55 years and older: Survival differences versus the young., PMID:40156602
Uracil processing by SMUG1 in the absence of UNG triggers homologous recombination and selectively kills BRCA1/2-deficient tumors., PMID:40010343
Aortic Valve Calcification Is Induced by the Loss of ALDH1A1 and Can Be Prevented by Agonists of Retinoic Acid Receptor Alpha: Preclinical Evidence for Drug Repositioning., PMID:39989358
Epistasis of ERAP1 With 4 Major Histocompatibility Complex Class I Alleles in Frontal Fibrosing Alopecia: A Genome-Wide Association Study Meta-Analysis., PMID:39937552
High-throughput in vitro drug screening and in vivo studies identify fenretinide as a brain-penetrant DMG therapeutic., PMID:39935375
Recent advances in recombinant production of soluble proteins in E. coli., PMID:39815265
Cytotoxic mechanisms of pemetrexed and HDAC inhibition in non-small cell lung cancer cells involving ribonucleotides in DNA., PMID:39814799
Computational study of the HLTF ATPase remodeling domain suggests its activity on dsDNA and implications in damage tolerance., PMID:39491691
Cryo-EM Structures of the Plasmodium falciparum Apicoplast DNA Polymerase., PMID:39490679
Chemoproteogenomic stratification of the missense variant cysteinome., PMID:39468056
Disordered regions of human eIF4B orchestrate a dynamic self-association landscape., PMID:39384813
MHC Hammer reveals genetic and non-genetic HLA disruption in cancer evolution., PMID:39358601
The Drug Transporter P-Glycoprotein and Its Impact on Ceramide Metabolism-An Unconventional Ally in Cancer Treatment., PMID:39337312
Datopotamab Deruxtecan Versus Chemotherapy in Previously Treated Inoperable/Metastatic Hormone Receptor-Positive Human Epidermal Growth Factor Receptor 2-Negative Breast Cancer: Primary Results From TROPION-Breast01., PMID:39265124
Transport of herbicides by PIN-FORMED auxin transporters., PMID:39257797
Deciphering the molecular landscape of the FAM72 gene family: Implications for stem cell biology and cancer., PMID:39236808
Altered expression of vesicular trafficking machinery in prostate cancer affects lysosomal dynamics and provides insight into the underlying biology and disease progression., PMID:39217195
Differential scanning calorimetry of proteins and Zimm-Bragg model in water., PMID:39181382
Identification of CDK4/6 Inhibitors as Small Molecule NLRP3 Inflammasome Activators that Facilitate IL-1β Secretion and T Cell Adjuvanticity., PMID:39162654
Loss of DNA glycosylases improves health and cognitive function in a C. elegans model of human tauopathy., PMID:39149885
Reinterpretation of prostate cancer pathology by Appl1, Sortilin and Syndecan-1 biomarkers., PMID:39117701
Programmable DNA pyrimidine base editing via engineered uracil-DNA glycosylase., PMID:39080265
Dominant suppressor genes of p53-induced apoptosis in Drosophila melanogaster., PMID:38985658
A modified glycosylase base editor without predictable DNA off-target effects., PMID:38946058
Trace elements alone or in mixtures associated with unconventional natural gas exploitation affect rat fetal steroidogenesis and testicular development in vitro., PMID:38901820
Activation of the integrated stress response in human hair follicles., PMID:38900734
Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling., PMID:38871738
Development of deaminase-free T-to-S base editor and C-to-G base editor by engineered human uracil DNA glycosylase., PMID:38851742
The fork remodeler helicase-like transcription factor in cancer development: all at once., PMID:38851303
Gene-Environment Interaction Between CYP1B1 and Oral Contraception on Frontal Fibrosing Alopecia., PMID:38809548
Enhancing genome editing in hPSCs through dual inhibition of DNA damage response and repair pathways., PMID:38734692
Development of TRIB3-Based Therapy as a Gene-Independent Approach to Treat Retinal Degenerative Disorders., PMID:38731938
m6A-methylated Lonp1 drives mitochondrial proteostasis stress to induce testicular pyroptosis upon environmental cadmium exposure., PMID:38703850
Unprocessed genomic uracil as a source of DNA replication stress in cancer cells., PMID:38688279
Regulatory role of PDK1 via integrated gene analysis of mitochondria-immune response in periodontitis., PMID:38657876
Crystal structure of the 3'→5' exonuclease from Methanocaldococcus jannaschii., PMID:38657529
Discovery and Optimization of Selective Brain-Penetrant EBP Inhibitors that Enhance Oligodendrocyte Formation., PMID:38470227
GRID1/GluD1 homozygous variants linked to intellectual disability and spastic paraplegia impair mGlu1/5 receptor signaling and excitatory synapses., PMID:38418578
Protein language models-assisted optimization of a uracil-N-glycosylase variant enables programmable T-to-G and T-to-C base editing., PMID:38377993
Exploring the role of sporadic BRAF and KRAS mutations during colorectal cancer pathogenesis: A spotlight on the contribution of the endosome-lysosome system., PMID:38290660
Acute myeloid leukemia stratifies as 2 clinically relevant sphingolipidomic subtypes., PMID:38170742
For research use only. Not for human or drug use.
