Catalog No.
YHC95301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly20-Asp97
Predicted molecular weight
35.31 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P12838
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
DEF4, Defensin, alpha 4, HP-4, HNP-4, Neutrophil defensin 4, DEFA4
Similarity of immune-associated markers in COVID-19 and Kawasaki disease: analyses from bioinformatics and machine learning., PMID:40383755
Identification and validation of diagnostic markers and drugs for pediatric bronchopulmonary dysplasia based on integrating bioinformatics and molecular docking analysis., PMID:40333951
Circulating RNA Markers Associated with Adenoma-Carcinoma Sequence in Colorectal Cancer., PMID:40003985
Increased Lipocalin 2 detected by RNA sequencing regulates apoptosis and ferroptosis in COPD., PMID:39462322
Revealing disease subtypes and heterogeneity in common variable immunodeficiency through transcriptomic analysis., PMID:39396099
Examining immune-inflammatory mechanisms of probiotic supplementation in depression: secondary findings from a randomized clinical trial., PMID:39048549
Blood gene expression biomarkers of response to anti-TNF drugs in pediatric inflammatory bowel diseases before initiation of treatment., PMID:38401525
Genes and Pathways Underpinning Klinefelter Syndrome at Bulk and Single-Cell Levels., PMID:38374521
Gene expression in multiple sclerosis during pregnancy based on integrated bioinformatics analysis., PMID:38154347
Biological analysis of the potential pathogenic mechanisms of Infectious COVID-19 and Guillain-Barré syndrome., PMID:38115996
Biomarker screening in fetal growth restriction based on multiple RNA-seq studies., PMID:37954535
Analysis of urine differential proteins in patients with allergic rhinitis., PMID:37426793
Exploring the bi-directional relationship and shared genes between depression and stroke via NHANES and bioinformatic analysis., PMID:37065487
Potential biomarkers for active renal involvement in systemic lupus erythematosus patients., PMID:36530895
MicroRNA-21-5p Regulates CD3+T Lymphocytes Through VCL and LTF in Patients with Immune Thrombocytopenia., PMID:35975534
Human transcriptomic response to periprosthetic joint infection., PMID:35306116
Interleukin-6 absence triggers intestinal microbiota dysbiosis and mucosal immunity in mice., PMID:35276634
Characterization of immune-related genes andimmune infiltration features for early diagnosis, prognosis and recognition of immunosuppression in sepsis., PMID:35272172
OLFM4 Regulates Lung Epithelial Cell Function in Sepsis-Associated ARDS/ALI via LDHA-Mediated NF-κB Signaling., PMID:34955649
Altered molecular pathways and prognostic markers in active systemic juvenile idiopathic arthritis: integrated bioinformatic analysis., PMID:34480465
Bioinformatic Analysis for Potential Biomarkers and Therapeutic Targets of T2DM-related MI., PMID:34413670
A pilot study of differential gene expressions in patients with cough variant asthma and classic bronchial asthma., PMID:33878997
Transcriptome profiling reveals target in primary myelofibrosis together with structural biology study on novel natural inhibitors regarding JAK2., PMID:33686952
Identification of Genes with Altered Methylation and Its Role in Early Diagnosis of Sepsis-Induced Acute Respiratory Distress Syndrome., PMID:33536775
Identification of key candidate biomarkers for severe influenza infection by integrated bioinformatical analysis and initial clinical validation., PMID:33448094
Identification of Significant Genes in HIV/TB via Bioinformatics Analysis., PMID:33067206
Formalin-fixed paraffin-embedded renal biopsy tissues: an underexploited biospecimen resource for gene expression profiling in IgA nephropathy., PMID:32938960
Identification of genes and pathways associated with subchondral bone in osteoarthritis via bioinformatic analysis., PMID:32925767
Time Series Gene Expression Profiles Analysis Identified Several Potential Biomarkers for Sepsis., PMID:32845709
The Cellular Transcriptome in the Maternal Circulation During Normal Pregnancy: A Longitudinal Study., PMID:31921132
Histone Methylation Mechanisms Modulate the Inflammatory Response of Periodontal Ligament Progenitors., PMID:31218921
Cellular Plasticity of Defa4Cre-Expressing Paneth Cells in Response to Notch Activation and Intestinal Injury., PMID:30827941
ATF4 Deficiency Promotes Intestinal Inflammation in Mice by Reducing Uptake of Glutamine and Expression of Antimicrobial Peptides., PMID:30452920
Significant transcriptome and cytokine changes in hepatitis B vaccine non-responders revealed by genome-wide comparative analysis., PMID:29580160
Antimicrobial peptide gene expression in periodontitis patients: A pilot study., PMID:29446150
RNA-Seq analysis of peripheral blood mononuclear cells reveals unique transcriptional signatures associated with disease progression in dengue patients., PMID:28683259
Sequencing and bioinformatics analysis of the differentially expressed genes in herniated discs with or without calcification., PMID:27959380
Behçet's: A Disease or a Syndrome? Answer from an Expression Profiling Study., PMID:26890122
Novel genes and variants associated with IgA nephropathy by co-segregating with the disease phenotypes in 10 IgAN families., PMID:26095808
Decreased Expression of Innate Immunity-Related Genes in Peripheral Blood Mononuclear Cells from Patients with IgG4-Related Disease., PMID:25973893
Urinary proteins, vitamin D and genetic polymorphisms as risk factors for febrile urinary tract infection and relation with bacteremia: a case control study., PMID:25807366
Gender differences of B cell signature in healthy subjects underlie disparities in incidence and course of SLE related to estrogen., PMID:24741625
Pro-inflammatory effects of matrix metalloproteinase 7 in acute inflammation., PMID:24129163
Differences and similarities in the transcriptional profile of peripheral whole blood in early and late-onset preeclampsia: insights into the molecular basis of the phenotype of preeclampsiaa., PMID:23793063
IGF-1 deficiency in combination with a low basic hBD-2 and hBD-3 gene expression might counteract malignant transformation in pleomorphic adenomas in vitro., PMID:22250586
Gene expression of oncogenes, antimicrobial peptides, and cytokines in the development of oral leukoplakia., PMID:20727496
Polymorphisms in PARP, IL1B, IL4, IL10, C1INH, DEFB1, and DEFA4 in meningococcal disease in three populations., PMID:20016407
Placenta-derived fetal specific mRNA is more readily detectable in maternal plasma than in whole blood., PMID:19516908
Signatures of natural selection are not uniform across genes of innate immune system, but purifying selection is the dominant signature., PMID:19359493
Copy number polymorphisms are not a common feature of innate immune genes., PMID:16617005
For research use only. Not for human or drug use.
