Catalog No.
YHC85801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly147-Cys403
Predicted molecular weight
29.92 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P11161
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
EGR-2, E3 SUMO-protein transferase ERG2, E3 SUMO-protein ligase EGR2, EGR2, Zinc finger protein Krox-20, AT591, Early growth response protein 2, KROX20
EGR2 O-GlcNAcylation orchestrates the development of protumoral macrophages to limit CD8+ T cell antitumor responses., PMID:40499546
Transcription Factors and Coregulators in Schwann Cell Differentiation, Myelination, and Remyelination: Implications for Peripheral Neuropathy., PMID:40452391
Multifaceted regulatory mechanisms of the EGR family in tumours and prospects for therapeutic applications (Review)., PMID:40444475
Genetic and clinical spectrum of early growth response 2-related Charcot-Marie-Tooth disease in a Brazilian cohort., PMID:40262821
Whole Transcriptome RNA-Seq Reveals Drivers of Pathological Dysfunction in a Transgenic Model of Alzheimer's Disease., PMID:40186694
Differential regulation of calcium-NFAT signaling pathway by Akt isoforms: unraveling effector dynamics and exhaustion of cytotoxic T lymphocytes in tumor microenvironment., PMID:40139836
EGR2 promotes liver cancer metastasis by enhancing IL-8 expression through transcription regulation of PDK4 in M2 macrophages., PMID:40139095
Unveiling the Hub Genes Associated with the Enhanced Effects of Selenium on Pancreas Function in Diabetic Mice., PMID:40128492
IER3: exploring its dual function as an oncogene and tumor suppressor., PMID:40090972
Erythropoietin decreases apoptosis and promotes Schwann cell repair and phagocytosis following nerve crush injury in mice., PMID:39896684
An Aligned-to-Random PLGA/Col1-PLGA/nHA Bilayer Electrospun Nanofiber Membrane Enhances Tendon-to-Bone Healing in a Murine Model., PMID:39876582
Mechanism of TGIF1 on glycolipid metabolism disorders in mice with type 2 diabetes., PMID:39842865
Edaravone Improves Motor Dysfunction Following Brachial Plexus Avulsion Injury in Rats., PMID:39791183
Indirectly acquired fear memories have distinct, sex-specific molecular signatures from directly acquired fear memories., PMID:39715176
Prediction of Lung Adenocarcinoma Driver Genes Through Protein-Protein Interaction Networks Utilizing GenePlexus., PMID:39696915
Overexpression of Egr1 Transcription Regulator Contributes to Schwann Cell Differentiation Defects in Neural Crest-Specific Adar1 Knockout Mice., PMID:39682701
Establishment and validation of diagnostic model in immunoglobulin A nephropathy based on weighted gene co-expression network analysis., PMID:39612439
CSF-1R blockade to alleviate azithromycin mediated immunosuppression in a mouse model of intracellular infection., PMID:39476565
Establishment of a Serum-Free Human iPSC-Derived Model of Peripheral Myelination., PMID:39437333
Enrichment of Cis-Acting Regulatory Elements in Differentially Methylated Regions Following Lipopolysaccharide Treatment of Bovine Endometrial Epithelial Cells., PMID:39337320
Transcription factor EGR2 alleviates autoimmune uveitis via activation of GDF15 to modulate the retinal microglial phenotype., PMID:39298490
Schwann cell-derived exosomes ameliorate peripheral neuropathy induced by ablation of dicer in Schwann cells., PMID:39285940
Loss of prohibitin 2 in Schwann cells dysregulates key transcription factors controlling developmental myelination., PMID:39215540
The differential expression of adipose tissue genes in short, medium and long-term periods after bariatric surgery., PMID:39198660
The impact of NUMB on chicken abdominal adipogenesis: A comprehensive analysis., PMID:39168214
RAB37-mediated autophagy guards ovarian homeostasis and function., PMID:39113565
Transcriptomic Hallmarks of Hypoxic-Ischemic Brain Injury: Insights from an in Vitro Model., PMID:39082286
EGR2 is an epigenomic regulator of phagocytosis and antifungal immunity in alveolar macrophages., PMID:39042472
Mitochondrial dysfunction and metabolic reprogramming induce macrophage pro-inflammatory phenotype switch and atherosclerosis progression in aging., PMID:38975335
Characterization of sciatic nerve myelin sheath during development in C57BL/6 mice., PMID:38951719
Inflammation and immunological disarrays are associated with acute exercise in type 2 diabetes., PMID:38932912
Egr2 to the rescue: nanoparticles revitalize natural killer cells in the fight against cancer., PMID:38886578
Gut microbiota depletion delays somatic peripheral nerve development and impairs neuromuscular junction maturation., PMID:38845453
Egr2 drives the differentiation of Ly6Chi monocytes into fibrosis-promoting macrophages in metabolic dysfunction-associated steatohepatitis in mice., PMID:38831027
Antitumor progenitor exhausted CD8+ T cells are sustained by TCR engagement., PMID:38816618
Deletion of TECRL promotes skeletal muscle repair by up-regulating EGR2., PMID:38753506
Yeast-derived particulate beta-glucan induced angiogenesis via regulating PI3K/Src and ERK1/2 signaling pathway., PMID:38685541
Early growth response protein 2 promotes partial epithelial-mesenchymal transition by phosphorylating Smad3 during renal fibrosis., PMID:38679230
Cenicriviroc, a CCR2/CCR5 antagonist, promotes the generation of type 1 regulatory T cells., PMID:38643381
Dysfunctional natural killer cells can be reprogrammed to regain anti-tumor activity., PMID:38637625
Neddylation orchestrates the complex transcriptional and posttranscriptional program that drives Schwann cell myelination., PMID:38608019
Loss of prohibitin 2 in Schwann cells dysregulates key transcription factors controlling developmental myelination., PMID:38562812
Identification of Hub Genes and Pathways of Middle Cerebral Artery Occlusion in Aged Rats Using the Gene Expression Omnibus Database., PMID:38505917
TEAD1 is crucial for developmental myelination, Remak bundles, and functional regeneration of peripheral nerves., PMID:38456457
Potential Alzheimer's early biomarkers in a transgenic rat model and benefits of diazoxide/dibenzoylmethane co-treatment on spatial memory and AD-pathology., PMID:38355687
PMP2 regulates myelin thickening and ATP production during remyelination., PMID:38311982
Deciphering Immune-related Gene Signatures in Diabetic Retinopathy: Insights from In silico Analysis and In vitro Experiment., PMID:38310446
Enantiomer-Dependent Supramolecular Immunosuppressive Modulation for Tissue Reconstruction., PMID:38306400
Identification of new subtypes and potential genetic signatures in triple-negative breast cancer using weighted gene co-expression network analysis., PMID:38305604
For research use only. Not for human or drug use.
