Catalog No.
YHC69301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Asp641
Predicted molecular weight
72.36 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P0DMV8
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
HSP70.1, HSP70-1, HSPA1, HSPA1A, Heat shock 70 kDa protein 1A, Heat shock 70 kDa protein 1, HSP72, HSX70
Heat shock protein 70 mitigates black carbon particles-induced cardiac damage., PMID:40412983
Recent insights into depression from transcriptomic analysis., PMID:40376285
Single-Cell RNA Sequencing Reveals the Immune Landscape of Granulomatous Mastitis., PMID:40338490
Identification of PANoptosis related biomarkers to predict hepatic ischemia‒reperfusion injury after liver transplantation., PMID:40316717
The Impact of Recreational Diving to a Depth of 40 m on Selected Intracellular DAMPs., PMID:40243713
PDT-regulated immune gene prognostic model reveals tumor microenvironment in colorectal cancer liver metastases., PMID:40240471
Endoplasmic reticulum stress-related prognosis signature characterizes the immune landscape and predicts the prognosis of colon adenocarcinoma., PMID:40236629
Identification of Oxidative Stress-Associated Biomarkers in Chronic Obstructive Pulmonary Disease: An Integrated Bioinformatics Analysis., PMID:40161396
Exploring the Molecular Intersection of Posterior Ocular Tuberculosis: Mycobacterium tuberculosis Proteins, Ocular Autoimmunity, and Immune Receptor Interactions., PMID:40151358
EIF4E1B interacts with HSPA1A and PPP2CA and is involved in mouse oocyte maturation and early embryonic development., PMID:40139147
Metabolomics- and Proteomics-Based Disease Diagnostic Classifier Model for the Prediction and Diagnosis of Colorectal Carcinoma., PMID:40108892
Integrative analysis of ubiquitination-related genes identifies HSPA1A as a critical regulator in colorectal cancer progression., PMID:40108105
Genome-wide profiling of a prognostic RNA-binding protein signature in esophageal cancer., PMID:40104740
Social disadvantage accelerates aging., PMID:40087516
Downregulated expression of dual-specificity phosphatase-1 in multiple myeloma as a predictor of poor survival outcomes., PMID:40077895
Heat Shock Protein Family A Member 1A Attenuates Apoptosis and Oxidative Stress via ERK/JNK Pathway in Hyperplastic Prostate., PMID:40066224
Heat Shock-Induced PI(4)P Increase Drives HSPA1A Translocation to the Plasma Membrane in Cancer and Stressed Cells through PI4KIII Alpha Activation., PMID:40027828
Descriptive Comparative Transcriptomic Analysis of Genotype IV SHEV ORF3-Expressing HepG2 Cells., PMID:40005777
Identification of key genes related to unilateral cryptorchidism in sheep by comprehensive transcriptomics and proteomics analyses., PMID:39972276
Single-cell transcriptomic analysis reveals distinct plasma cell populations in chronic thromboembolic pulmonary hypertension., PMID:39965671
HSPA1A inhibits pyroptosis and neuroinflammation after spinal cord injury via DUSP1 inhibition of the MAPK signaling pathway., PMID:39924492
N6-methyladenosine (m6A) modification regulates HSPA1A and HSPA1B expression in Müller cells under high glucose stress., PMID:39922527
A cellular model of TDP-43 induces phosphorylated TDP-43 aggregation with distinct changes in solubility and autophagy dysregulation., PMID:39887552
Novel genetic insight for psoriasis: integrative genome-wide analyses in 863 080 individuals and proteome-wide Mendelian randomization., PMID:39883516
Sex-specific transcriptomic profiling reveals key players in bone loss associated with Alzheimer's disease., PMID:39875754
Investigating the Impact of B Cell-Related Genes on Colorectal Cancer Immunosuppressive Environment and Immunotherapy Evasion., PMID:39868510
Identification of key genes associated with oxidative stress in ischemic stroke via bioinformatics integrated analysis., PMID:39806309
Spatial Genomics Identifies Heat Shock Proteins as Key Molecular Changes Associated to Adipose Periprostatic Space Invasion in Prostate Cancer., PMID:39796635
RiboTag RNA Sequencing Identifies Local Translation of HSP70 in Astrocyte Endfeet After Cerebral Ischemia., PMID:39796165
A pilot study of transcriptomic preimplantation genetic testing (PGT-T): towards a new step in embryo selection?, PMID:39719045
Heat-Induced Phosphatidylserine Changes Drive HSPA1A's Plasma Membrane Localization., PMID:39713339
Investigating the potential role of capsaicin in facilitating the spread of coxsackievirus B3 via extracellular vesicles., PMID:39677700
Integrative Investigation of Flavonoids Targeting YBX1 Protein-Protein Interaction Network in Breast Cancer: From Computational Analysis to Experimental Validation., PMID:39565541
Embryonic Temperature Influences the Mucosal Responses of Atlantic Salmon Alevins to a Bacterial Challenge., PMID:39560796
ATF5-mediated mitochondrial unfolded protein response protects against Pb-induced mitochondria damage in SH-SY5Y cell., PMID:39547369
Integrative multiomic analysis unveils the molecular nexus of mitochondrial dysfunction in the pathogenesis of age-related macular degeneration., PMID:39490725
RNA sequencing comparing centenarian and middle-aged women lymphoblastoid cell lines identifies age-related dysregulated expression of genes encoding selenoproteins, heat shock proteins, CD99, and BID., PMID:39445501
Mtb/HIV co-infection immune microenvironment subpopulations heterogeneity., PMID:39405943
Effects of treadmill exercise on endoplasmic reticulum protein folding and endoplasmic reticulum-associated protein degradation pathways in APP/PS1 mice., PMID:39397952
Bulk integrated single-cell-spatial transcriptomics reveals the impact of preoperative chemotherapy on cancer-associated fibroblasts and tumor cells in colorectal cancer, and construction of related predictive models using machine learning., PMID:39374811
[Knockout of Hsp70 Genes Modulates Age-Related Transcriptomic Changes in Leg Muscles and Reduces the Locomotion Speed and Lifespan of Drosophila melanogaster]., PMID:39355882
The protective effects of esculetin against Doxorubicin-Induced hepatotoxicity in rats: Insights into the modulation of Caspase, FOXOs, and heat shock protein pathways., PMID:39305037
Protein Misfolding Releases Human HSF1 from HSP70 Latency Control., PMID:39122169
Insights on early response to acute heat shock of bovine mammary epithelial cells through a multimethod approach., PMID:39116469
[Central inflammatory mechanism of celastrol in intervention of obesity-depression comorbidity in mice from amygdala-dorsal raphe nucleus]., PMID:39099356
Interaction between microglial cells and CD1C+ B dendritic cells leads to CD8+ T cells depletion during the early stages of renal clear cell carcinoma., PMID:39093774
Exploring Mutation-Driven Changes in the ATP-ADP Conformational Cycle of Human Hsp70 by All-Atom MD Adaptive Sampling., PMID:39091167
Genome-Wide Identification and Interaction Analysis of Turbot Heat Shock Protein 40 and 70 Families Suggest the Mechanism of Chaperone Proteins Involved in Immune Response after Bacterial Infection., PMID:39063205
The regulation of the thermal stability and affinity of the HSPA5 (Grp78/BiP) by clients and nucleotides is modulated by domains coupling., PMID:39009203
Exploring the Roles of Key Mediators IKBKE and HSPA1A in Alzheimer's Disease and Hepatocellular Carcinoma through Bioinformatics Analysis., PMID:39000042
For research use only. Not for human or drug use.
