Catalog No.
YHC35601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asn40-Lys491
Predicted molecular weight
52.76 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P08697
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Alpha-2-PI, Serpin F2, Alpha-2-plasmin inhibitor, Alpha-2-AP, Alpha-2-antiplasmin, AAP, PLI, SERPINF2,A2AP
Transcriptome and proteome profile analysis of the regulation of chicken ovarian development., PMID:40466268
Unveiling the levels and significance of different serpin family proteins in aqueous humor dynamics., PMID:40389884
Discovery of novel ancestry specific genes for androgens and hypogonadism in Million Veteran Program Men., PMID:40316537
Immune status assessment based on plasma proteomics with meta graph convolutional networks., PMID:40211143
Uncovering leading compounds for alzheimer's disease treatment: mendelian randomization and virtual screening insights into plasma protein modulation., PMID:40186323
Identification and Validation of a Novel Prognostic Signature of Gastric Cancer Based on Seven Complement System-Related Genes: An Integrated Analysis., PMID:39964966
Gut Microbiome-Driven metabolites influence skin pigmentation in TYRP1 mutant Oujiang Color Common Carp., PMID:39094713
Discovery of candidate biomarkers from plasma-derived extracellular vesicles of patients with cirrhosis and hepatocellular carcinoma: an exploratory proteomic study., PMID:39011654
Conjugated linoleic acid (CLA) modulates bovine peripheral blood mononuclear cells (PBMC) proteome in vitro., PMID:38909954
Comparison of mucus and serum biomarker sampling in chronic rhinosinusitis with nasal polyps., PMID:37990964
UMI-77 Modulates the Complement Cascade Pathway and Inhibits Inflammatory Factor Storm in Sepsis Based on TMT Proteomics and Inflammation Array Glass Chip., PMID:37830896
Combination of HBA1, TTR, and SERPINF2 in plasma defines phenotype correlated with severe burn outcome., PMID:37502255
Proteomic Characterization of SAS Cell-Derived Extracellular Vesicles in Relation to Both BPA and Neutron Irradiation Doses., PMID:37371031
Rare inherited coagulation and fibrinolytic defects that challenge diagnostic laboratories., PMID:37211424
Transcriptomic evidence for tumor-specific beneficial or adverse effects of TGFβ pathway inhibition on the prognosis of patients with liver cancer., PMID:37195148
A liver secretome gene signature-based approach for determining circulating biomarkers of NAFLD severity., PMID:36260611
Circuit-wide proteomics profiling reveals brain region-specific protein signatures in the male WKY rats with endogenous depression., PMID:36162674
Alterations in the kallikrein-kinin system predict death after heart transplant., PMID:35986069
Novel Diagnostic Biomarkers for High-Grade Serous Ovarian Cancer Uncovered by Data-Independent Acquisition Mass Spectrometry., PMID:35939567
Genome-Wide Identification of Associations of Circulating Molecules With Spontaneous Coronary Artery Dissection and Aortic Aneurysm and Dissection., PMID:35571188
Serpin Signatures in Prion and Alzheimer's Diseases., PMID:35416570
Molecular Composition of Serum Exosomes Could Discriminate Rectal Cancer Patients with Different Responses to Neoadjuvant Radiotherapy., PMID:35205741
Targeted proteomics for evaluating risk of venous thrombosis following traumatic lower-leg injury or knee arthroscopy., PMID:34919779
Pre-Operative Plasma Extracellular Vesicle Proteins are Associated with a High Risk of Long Term Secondary Major Cardiovascular Events in Patients Undergoing Carotid Endarterectomy., PMID:34511318
Tranexamic acid administration in the field does not affect admission thromboelastography after traumatic brain injury., PMID:33105308
Decrease in matrix metalloproteinase‑3 activity in systemic sclerosis fibroblasts causes α2‑antiplasmin and extracellular matrix deposition, and contributes to fibrosis development., PMID:32945390
28-day thawed plasma maintains α2 -antiplasmin levels and inhibits tPA-induced fibrinolysis., PMID:32894784
Analysis of plasma protein biomarkers in childhood onset multiple sclerosis., PMID:32841722
Extracellular vesicle Cystatin C and CD14 are associated with both renal dysfunction and heart failure., PMID:32648717
Liver gene regulation of hemostasis-related factors is altered by experimental snake envenomation in mice., PMID:32479494
Label free shotgun proteomics for the identification of protein biomarkers for beef tenderness in muscle and plasma of heifers., PMID:32058039
A rare cause of bleeding in two Indian families with congenital alpha-2-antiplasmin deficiency., PMID:31577375
A novel variant causing α2 antiplasmin deficiency: case report and experience in a UK centre., PMID:31441040
Prothrombotic clot properties can predict venous ulcers in patients following deep vein thrombosis: a cohort study., PMID:31432450
Abnormal fibrinolysis recognized by thromboelastography in a case of severe bleeding with normal coagulation and platelet function, leads to detection of a novel SERPINF2 variant causing severe alpha-2-antiplasmin deficiency., PMID:31282989
Depletion of β3-adrenergic receptor induces left ventricular diastolic dysfunction via potential regulation of energy metabolism and cardiac contraction., PMID:30790654
Protein expression in the liver and blood serum in chickens in response to Salmonella Enteritidis infection., PMID:30458997
Increased urokinase and consumption of α2 -antiplasmin as an explanation for the loss of benefit of tranexamic acid after treatment delay., PMID:30451372
Genetic Regulation of Pigment Epithelium-Derived Factor (PEDF): An Exome-Chip Association Analysis in Chinese Subjects With Type 2 Diabetes., PMID:30305369
Association of imbalanced sex hormone production with excessive procoagulation factor SerpinF2 in preeclampsia., PMID:30020241
Proteomic Alterations in Aqueous Humor From Patients With Primary Open Angle Glaucoma., PMID:29847670
A novel allele variant of the SERPINF2 gene responsible for severe plasmin inhibitor (α2-antiplasmin) deficiency in an Italian patient., PMID:29656168
Amorphous protein aggregates stimulate plasminogen activation, leading to release of cytotoxic fragments that are clients for extracellular chaperones., PMID:28710283
A proteomic signature of ovarian cancer tumor fluid identified by highthroughput and verified by targeted proteomics., PMID:27222041
A panel of glycoproteins as candidate biomarkers for early diagnosis and treatment evaluation of B-cell acute lymphoblastic leukemia., PMID:26823978
Extracellular Vesicle Proteins Associated with Systemic Vascular Events Correlate with Heart Failure: An Observational Study in a Dyspnoea Cohort., PMID:26820481
Screening for potential serum biomarkers in rat mesangial proliferative nephritis., PMID:26791873
Relationships between Circulating Urea Concentrations and Endometrial Function in Postpartum Dairy Cows., PMID:26479384
Bayesian phylogeny analysis of vertebrate serpins illustrates evolutionary conservation of the intron and indels based six groups classification system from lampreys for ∼500 MY., PMID:26157611
Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci., PMID:25129075
For research use only. Not for human or drug use.
