Catalog No.
YHC38601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Leu434
Predicted molecular weight
49.58 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P09104
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
2-phospho-D-glycerate hydro-lyase, NSE, ENO2, Neural enolase, Gamma-enolase, Neuron-specific enolase, Enolase 2
The 1p/19q co-deletion induces targetable and imageable vulnerabilities in glucose metabolism in oligodendrogliomas., PMID:40475477
Analysing Differential Alternative Splicing Events and Their Impact on Retinoblastoma Progression Using RNA-seq Metadata., PMID:40439392
The serum proteomic profile in patients with migraine., PMID:40196050
Identification and analysis of oxidative stress-related genes in endometriosis., PMID:40124382
The utility of brain biomarkers in predicting survival and neurological outcomes in pediatric patients after cardiac arrest: A systematic review and meta-analysis., PMID:40062924
Co-modulation of a circular form of PCDH11Y during neuroendocrine differentiation of prostate cancer., PMID:40008007
Disruption of the eEF1A1/ARID3A/PKC-δ Complex by Neferine Inhibits Macrophage Glycolytic Reprogramming in Atherosclerosis., PMID:39973763
ENO2-Regulated Glycolysis in Endothelial Cells Contributes to FGF2-Induced Retinal Neovascularization., PMID:39854009
Modulation of Stemness and Differentiation Regulators by Valproic Acid in Medulloblastoma Neurospheres., PMID:39851500
Gene expression and mucilage adaptations to salinity in germination of extreme halophyte Schrenkiella parvula seeds., PMID:39832394
Prognostic significance of D-dimer, neuron-specific enolase, and lactate dehydrogenase changes in patients with severe traumatic brain injury: a logistic regression analysis., PMID:39828838
Flower-like tailored carbon nitride oligomer as an excellent aggregation-induced electrochemiluminescence emitter for sensitive immunoassay of neuron-specific enolase via dual quenching by bimetallic phenolic networks., PMID:39756192
Alternative splicing landscape in mouse skeletal muscle and adipose tissue: Effects of intermittent fasting and exercise., PMID:39725041
Tanshinone I reprograms glycolysis metabolism to regulate histone H3 lysine 18 lactylation (H3K18la) and inhibits cancer cell growth in ovarian cancer., PMID:39710022
The serum biomarkers NSE and S100B predict intracranial complications and in-hospital survival in patients undergoing veno-venous ECMO., PMID:39695311
Characterization of Epithelial-Mesenchymal and Neuroendocrine Differentiation States in Pancreatic and Small Cell Ovarian Tumor Cells and Their Modulation by TGF-β1 and BMP-7., PMID:39682758
Casticin inhibits proliferation of Non-small cell lung cancer cells through regulating reprogramming of glucose metabolism., PMID:39647464
The 419th Aspartic Acid of Neural Membrane Protein Enolase 2 Is a Key Residue Involved in the Axonal Growth of Motor Neurons Mediated by Interaction between Enolase 2 Receptor and Extracellular Pgk1 Ligand., PMID:39409082
Screening of differential gene expression patterns through survival analysis for diagnosis, prognosis and therapies of clear cell renal cell carcinoma., PMID:39348357
ZFP64 drives glycolysis-mediated stem cell-like properties and tumorigenesis in breast cancer., PMID:39294751
The novel HSP90 monoclonal antibody 9B8 ameliorates articular cartilage degeneration by inhibiting glycolysis via the HIF-1 signaling pathway., PMID:39229534
Key genes and regulatory networks for diabetic retinopathy based on hypoxia-related genes: a bioinformatics analysis., PMID:39156775
Can levels of neuron-specific enolase be used in the diagnostic workup of possible cauda equina syndrome?, PMID:39153847
Development and Validation of Diagnostic Models for Transcriptomic Signature Genes for Multiple Tissues in Osteoarthritis., PMID:39099665
Interference with ENO2 promotes ferroptosis and inhibits glycolysis in clear cell renal cell carcinoma by regulating Hippo‑YAP1 signaling., PMID:39091581
Clinical value of serum neuron-specific enolase in sepsis-associated encephalopathy: a systematic review and meta-analysis., PMID:39039544
PTGES2 and RNASET2 identified as novel potential biomarkers and therapeutic targets for basal cell carcinoma: insights from proteome-wide mendelian randomization, colocalization, and MR-PheWAS analyses., PMID:39035989
Immunoaffinity Intact-Mass Spectrometry for the Detection of Endogenous Concentrations of the Acetylated Protein Tumor Biomarker Neuron Specific Enolase., PMID:39013105
Reprogramming of Energy Metabolism in Human PKD1 Polycystic Kidney Disease: A Systems Biology Analysis., PMID:39000280
BNIP3-mediated mitophagy boosts the competitive growth of Lenvatinib-resistant cells via energy metabolism reprogramming in HCC., PMID:38969639
Evaluation of secretome biomarkers in glioblastoma cancer stem cells: A bioinformatics analysis., PMID:38967113
HOXC6-mediated transcriptional activation of ENO2 promotes oral squamous cell carcinoma progression through the Warburg effect., PMID:38923759
CAR+ extracellular vesicles predict ICANS in patients with B cell lymphomas treated with CD19-directed CAR T cells., PMID:38833312
Correlations of Expression Levels of Lung Cancer Marker Gene Eno2 and Genes of Carcinogenesis and Apoptosis in the Hypothalamus of Mice with Depression-Like Behavior., PMID:38730106
Circular RNA circESYT2 serves as a microRNA-665 sponge to promote the progression of hepatocellular carcinoma through ENO2., PMID:38710213
Serum Neuron-Specific Enolase as a Biomarker of Neonatal Brain Injury-New Perspectives for the Identification of Preterm Neonates at High Risk for Severe Intraventricular Hemorrhage., PMID:38672451
PROTEIN L-ISOASPARTYL METHYLTRANSFERASE protects enolase dysfunction by repairing isoaspartyl-induced damage and is positively implicated in agronomically important seed traits., PMID:38625788
Identification of key genes and signalling pathways in clear cell renal cell carcinoma: An integrated bioinformatics approach., PMID:38427469
'Evaluation of beta-2-microglobulin and neuron-specific enolase as prognostic factors in patients over 65 years of age with frailty syndrome hospitalized for acute coronary syndrome'., PMID:38411209
USP21 deubiquitinates and stabilizes HSP90 and ENO1 to promote aerobic glycolysis and proliferation in cholangiocarcinoma., PMID:38385089
Neuron-specific enolase at admission as a predictor for stroke volume, severity and outcome in ischemic stroke patients: a prognostic biomarker review., PMID:38302568
Candida albicans increases the aerobic glycolysis and activates MAPK-dependent inflammatory response of liver sinusoidal endothelial cells., PMID:38296157
Tumor-derived Exosomal ENO2 Modulates Polarization of Tumor-associated Macrophages through Reprogramming Glycolysis to Promote Progression of Diffuse Large B-cell Lymphoma., PMID:38250157
Augmentation of scleral glycolysis promotes myopia through histone lactylation., PMID:38232735
Role of neuron-specific enolase as a prognostic marker in pediatric cardiac arrest., PMID:38057235
Nicotine Exposure in a Phencyclidine-Induced Mice Model of Schizophrenia: Sex-Selective Medial Prefrontal Cortex Protein Markers of the Combined Insults in Adolescent Mice., PMID:37834084
Correlation Between Quantitative Background Suppression on EEG and Serum NSE in Patients With Hypoxic-ischemic Encephalopathy., PMID:37756018
High-Fat Mouse Model to Explore the Relationship between Abnormal Lipid Metabolism and Enolase in Pancreatic Cancer., PMID:37731842
Confounders for prognostic accuracy of neuron-specific enolase after cardiac arrest: A retrospective cohort study., PMID:37683997
ENO2-derived phosphoenolpyruvate functions as an endogenous inhibitor of HDAC1 and confers resistance to antiangiogenic therapy., PMID:37667133
For research use only. Not for human or drug use.
