Catalog No.
YHC33102
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly293-Ala407
Predicted molecular weight
15.11 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P08476
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
EDF, Erythroid differentiation protein, Activin beta-A chain, INHBA, Inhibin beta A chain
INHBA, transcriptionally activated by SPI1, facilitates gastric cancer progression by inducing macrophage recruitment and M2 polarization via activating the TGF-β signaling to increase CCL2., PMID:40132395
Short-term overloading exercise attenuates articular chondrocyte features partly via synovium-cartilage interactions mediated by inhibin subunit beta A., PMID:40000838
Comprehensive analysis of inhibin-β A as a potential biomarker for gastrointestinal tract cancers through bioinformatics approaches., PMID:39774945
Identification and Validation of Serum Biomarkers to Improve Colorectal Cancer Diagnosis., PMID:39628390
DNA hypomethylation of INHBA promotes tumor progression and predicts prognosis and immune status of gastric cancer., PMID:39543755
Molecular mechanisms and clinicopathological characteristics of inhibin βA in thyroid cancer metastasis., PMID:39301627
Activin levels correlate with lymphocytic infiltration in epithelial ovarian cancer., PMID:39248018
Discovery of PELATON links to the INHBA gene in the TGF-β pathway in colorectal cancer using a combination of bioinformatics and experimental investigations., PMID:38735606
Inhibin A contributes to the tumorigenesis of oral squamous cell carcinoma by KIAA1429-mediated m6A modification., PMID:38531807
Elevated INHBA Promotes Tumor Progression of Cervical Cancer., PMID:38419562
INHBA is Enriched in HPV-negative Oropharyngeal Squamous Cell Carcinoma and Promotes Cancer Progression., PMID:38329386
FOXA2-initiated transcriptional activation of INHBA induced by methylmalonic acid promotes pancreatic neuroendocrine neoplasm progression., PMID:38252148
The New Role of HNF1A-NAS1/miR-214/INHBA Signaling Axis in Colorectal Cancer., PMID:38062804
Circulating Activin A, Kidney Fibrosis, and Adverse Events., PMID:37983094
Comparative proteomics of ovaries elucidated the potential targets related to ovine prolificacy., PMID:37675075
Single-cell transcriptomics of human cholesteatoma identifies an activin A-producing osteoclastogenic fibroblast subset inducing bone destruction., PMID:37537159
Impaired angiogenesis in diabetic critical limb ischemia is mediated by a miR-130b/INHBA signaling axis., PMID:37097749
MiR-29c-5p regulates the function of buffalo granulosa cells to induce follicular atresia by targeting INHBA., PMID:37086585
Uncovering Tumor-Promoting Roles of Activin A in Pancreatic Ductal Adenocarcinoma., PMID:37083240
Correlation of INHBA Overexpression with Pathological Features, Antitumor Immune Response and Clinical Prognosis in Cervical Cancer., PMID:36984496
In vivo induction of activin A-producing alveolar macrophages supports the progression of lung cell carcinoma., PMID:36650150
Increased Expression of INHBA Is Correlated With Poor Prognosis and High Immune Infiltrating Level in Breast Cancer., PMID:36304286
BMSCs overexpressed ISL1 reduces the apoptosis of islet cells through ANLN carrying exosome, INHBA, and caffeine., PMID:36190571
Genomic and transcriptomic analyses reveal genetic adaptation to cold conditions in the chickens., PMID:36126832
Prognostic impact of activin subunit inhibin beta A in gastric and esophageal adenocarcinomas., PMID:36064338
Upregulation of INHBA mediated by the transcription factor BHLHE40 promotes colon cancer cell proliferation and migration., PMID:35689549
CGB5, INHBA and TRAJ19 Hold Prognostic Potential as Immune Genes for Patients with Gastric Cancer., PMID:35624327
Increase in inhibin beta A/Activin-A expression in the human epidermis and the suppression of epidermal stem/progenitor cell proliferation with aging., PMID:35610160
Activin-A impairs CD8 T cell-mediated immunity and immune checkpoint therapy response in melanoma., PMID:35580932
Hop and artichoke extracts inhibit expression of extracellular matrix components in uterine leiomyoma cells., PMID:35559863
Comprehensive analysis of INHBA: A biomarker for anti-TGFβ treatment in head and neck cancer., PMID:35521936
CircTHBS1 drives gastric cancer progression by increasing INHBA mRNA expression and stability in a ceRNA- and RBP-dependent manner., PMID:35338119
DNA Hypomethylation Is Associated with the Overexpression of INHBA in Upper Tract Urothelial Carcinoma., PMID:35216189
M2-phenotype tumour-associated macrophages upregulate the expression of prognostic predictors MMP14 and INHBA in pancreatic cancer., PMID:35150061
Visceral adipose tissue remodeling in pancreatic ductal adenocarcinoma cachexia: the role of activin A signaling., PMID:35102236
Circular RNA 0000654 facilitates the growth of gastric cancer cells through absorbing microRNA-149-5p to up-regulate inhibin-beta A., PMID:35100076
Dysregulation of Npas4 and Inhba expression and an altered excitation-inhibition balance are associated with cognitive deficits in DBA/2 mice., PMID:35042829
Identification of hub genes and construction of an mRNA-miRNA-lncRNA network of gastric carcinoma using integrated bioinformatics analysis., PMID:34968391
Inhibin subunit beta A promotes cell proliferation and metastasis of breast cancer through Wnt/β-catenin signaling pathway., PMID:34889158
Inhibin βA is an independent prognostic factor that promotes invasion via Hippo signaling in non‑small cell lung cancer., PMID:34505633
TGF-β/activin signaling promotes CDK7 inhibitor resistance in triple-negative breast cancer cells through upregulation of multidrug transporters., PMID:34481843
Inhibin β-A (INHBA) induces epithelial-mesenchymal transition and accelerates the motility of breast cancer cells by activating the TGF-β signaling pathway., PMID:34346300
Identification of genomic imbalances (CNVs as well as LOH) in sertoli cell only syndrome cases through cytoscan microarray., PMID:34274474
INHBA promotes the proliferation, migration and invasion of colon cancer cells through the upregulation of VCAN., PMID:34130530
Effect of Mouse Ovarian Vitrification on Promoter Methylation of Inhba and Inhbb in Granulosa Cells of Follicles., PMID:33970982
An endothelial activin A-bone morphogenetic protein receptor type 2 link is overdriven in pulmonary hypertension., PMID:33741934
Identifying the tumor-progressive gene expression profile in high-risk papillary thyroid cancer., PMID:33733290
GM-CSF Expression and Macrophage Polarization in Joints of Undifferentiated Arthritis Patients Evolving to Rheumatoid Arthritis or Psoriatic Arthritis., PMID:33679701
RETRACTED: microRNA-6785-5p-loaded human umbilical cord mesenchymal stem cells-derived exosomes suppress angiogenesis and metastasis in gastric cancer via INHBA., PMID:33609542
Prediction of Calving to Conception Interval Length Using Algorithmic Analysis of Endometrial mRNA Expression in Bovine., PMID:33478124
For research use only. Not for human or drug use.
