Catalog No.
YHC24001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys481-Pro667
Predicted molecular weight
22.71 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P07225
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PROS1, Vitamin K-dependent protein S, PROS
Genotype versus laboratory phenotype correlation of defects in natural anticoagulants in patients with venous thromboembolism., PMID:40436275
Diagnosing protein S deficiency - Navigating challenges., PMID:40419135
Novel Association of Thrombophilic PROS1, PROC and CPB2 Genes Polymorphisms with Recurrent Spontaneous Miscarriage Women in Jordan., PMID:40232193
Population-Scale Studies of Protein S Abnormalities and Thrombosis., PMID:40029645
PTP Inhibition Improves the Macrophage Antitumor Immune Response and the Efficacy of Chemo- and Radiotherapy., PMID:39937118
Mechanistic insights into PROS1 inhibition of bladder cancer progression and angiogenesis via the AKT/GSK3β/β-catenin pathway., PMID:39922934
Two patients with protein S deficiency and cerebral venous sinus thrombosis: nonsense mutations of the PROS1 gene may account for these deficiencies., PMID:39918901
New potential ligand-receptor axis involved in tissue repair as therapeutic targets in progressive multiple sclerosis., PMID:39892997
Distinct TYRO3 and PROS1 expression levels contribute to preeclampsia pathogenesis., PMID:39878883
A new hereditary PROS1 gene mutation caused isolated cortical venous thrombosis., PMID:39798525
In Situ Proefferocytosis Microspheres as Macrophage Polarity Converters Accelerate Osteoarthritis Treatment., PMID:39780612
[Hereditary protein S deficiency in a patient with prominent mesenteric venous thrombosis: A case report]., PMID:39690778
Assessment of a next generation sequencing gene panel strategy in 133 patients with negative thrombophilia screening., PMID:39675565
Loss of protein C vs protein S results in discrepant thrombotic phenotypes., PMID:39657127
Ovarian expression of MerTK and its ligand Pros1 in non-pregnant estrus and pregnant mice., PMID:39612024
Proteomic identification of potential biomarkers for heat tolerance in Caracu beef cattle using high and low thermotolerant groups., PMID:39538142
A Computational Approach to Characterize the Protein S-Mer Tyrosine Kinase (PROS1-MERTK) Protein-Protein Interaction Dynamics., PMID:39535659
Frequency and Association of Polymorphisms in F2, F7, and PROS1 Coagulation Genes with Disease Severity in Coronavirus Disease 2019., PMID:39497411
Case Report: PROS1 (c.76+2_76+3del) pathogenic mutation causes pulmonary embolism., PMID:39465133
MerTK signaling in human primary T cells modulates memory potential and improves recall response., PMID:39422252
SARS-CoV-2 Vaccine Improved Hemostasis of a Patient with Protein S Deficiency: A Case Report., PMID:39409046
Multifocal osteonecrosis due to the synergistic impact of inherited thrombophilia, autoimmunity, and pregnancy: A case report., PMID:39363854
Development of an assay using a modified coagulation factor V to measure protein S activity., PMID:39243859
Integrated data driven analysis identifies potential candidate genes associated with PCOS., PMID:39243549
Investigation of a novel PROS1 splicing variant in a patient with protein S deficiency., PMID:39060248
A Novel Splice Donor Site Mutation Leading to Inherited Type I Protein S Deficiency., PMID:38919323
The risk profiles of pregnancy-related cerebral venous thrombosis: a retrospective study in a comprehensive hospital., PMID:38822265
The Dysregulation of the Monocyte-Dendritic Cell Interplay Is Associated with In-Hospital Mortality in COVID-19 Pneumonia., PMID:38731010
Downregulation of protein S in patients with severe COVID-19 augments the prothrombotic state., PMID:38703586
Axl as a potential therapeutic target for adamantinomatous craniopharyngiomas: Based on single nucleus RNA-seq and spatial transcriptome profiling., PMID:38677641
Regulation of Mertk Surface Expression via ADAM17 and γ-Secretase Proteolytic Processing., PMID:38673989
The Vitamin K-Dependent Anticoagulant Factor, Protein S, Regulates Vascular Permeability., PMID:38666935
Identification of Critical Genes Differentiating Stable and Unstable Atherosclerotic Plaques: A Bioinformatic and Computational Analysis., PMID:38639275
PROS1 is a crucial gene in the macrophage efferocytosis of diabetic foot ulcers: a concerted analytical approach through the prisms of computer analysis., PMID:38613800
Duodenal mucosa of untreated celiac disease patients has altered expression of the GAS6 and PROS1 and the negative regulator tyrosine kinase TAM receptors subfamily., PMID:38575045
The TAM Subfamily of Receptor Tyrosine Kinases: The Early Years., PMID:38542343
The Protein S Erlangen Mutation PROS1c.1904T>C (F635S) Suppresses Secretion., PMID:38469768
Lessons from an elderly patient with pulmonary embolism caused by protein S deficiency: a case report., PMID:38414076
In Situ Endothelial SARS-CoV-2 Presence and PROS1 Plasma Levels Alteration in SARS-CoV-2-Associated Coagulopathies., PMID:38398746
Construction and evaluation of endometriosis diagnostic prediction model and immune infiltration based on efferocytosis-related genes., PMID:38370978
MICA+ Tumor Cell Upregulated Macrophage-Secreted MMP9 via PROS1-AXL Axis to Induce Tumor Immune Escape in Advanced Hepatocellular Carcinoma (HCC)., PMID:38254761
Analysis of PROS1 mutations and clinical characteristics in three Chinese families with hereditary protein S deficiency., PMID:38175252
A Rare Case with Pulmonary Embolism and Literature Review., PMID:38084685
Case Report: PROS1 (p.Leu584Arg) pathogenic mutation causes portal and superior mesenteric venous thromboembolism., PMID:38034377
A Systems Biology Approach for Investigating Significant Biomarkers and Drug Targets Common Among Patients with Gonorrhea, Chlamydia, and Prostate Cancer: A Pilot Study., PMID:38033384
Development of purpura fulminans by Candida glabrata and Mucormycosis infection post-surgery., PMID:37954167
HMGN2 and Histone H1.2: potential targets of a novel probiotic mixture for seasonal allergic rhinitis., PMID:37869664
Screening tumor stage-specific candidate neoantigens in thyroid adenocarcinoma using integrated exome and transcriptome sequencing., PMID:37854594
PROS1, a clinical prognostic biomarker and tumor suppressor, is associated with immune cell infiltration in breast cancer: A bioinformatics analysis combined with experimental verification., PMID:37827342
[PROSI Mutation With Clinical Heterogeneity in Protein S Deficiency:Report of One Case]., PMID:37621108
For research use only. Not for human or drug use.
