Catalog No.
YHC19801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met433-Ala782
Predicted molecular weight
40.63 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P06396
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Gelsolin, Brevin, GSN, ADF, AGEL, Actin-depolymerizing factor
Gelsolin Facilitates Estrogen Receptor Beta Nuclear Translocation and Transcriptional Repression of Genes Associated with Alzheimer Disease., PMID:40475329
Gelsolin's Protective Role in MASH through F-Actin Regulation and P53 Degradation., PMID:40390546
Phase II study of venetoclax added to bendamustine and obinutuzumab in patients with high-risk follicular lymphoma as front-line therapy: PrE0403., PMID:40355425
Linking Parkinson's disease and melanoma: the impact of copper-driven cuproptosis and related mechanisms., PMID:40221422
Correction of dysregulated lipid metabolism normalizes gene expression in oligodendrocytes and prolongs lifespan in female poly-GA C9orf72 mice., PMID:40216746
Xin-shu-bao tablets ameliorates ventricular remodeling against HFrEF via PPARγ/MFGE8 pathway based on MALDI-MSI and lipidomics., PMID:40216048
Whole-exome sequencing screening for candidate genes and potential pathogenic variants associated with early-onset high myopia in 47 Chinese families., PMID:40175531
Gelsolin as a predictor marker for late-onset fetal growth restriction and adverse neonatal outcomes: A prospective cross-sectional study., PMID:40174268
[Tissue and plasma proteomic signatures associated with the risk of gastric cancer]., PMID:40107780
Integrated Proteomics and Lipidomics Analysis of Hippocampus to Reveal the Metabolic Landscape of Epilepsy., PMID:40092809
From inflammation to remodelling: A novel BASP1+ monocyte subset as a catalyst for acute aortic dissection., PMID:40057028
Significance of Gelsolin Superfamily Genes in Diagnosis, Prognosis and Immune Microenvironment Regulation for Endometrial Cancer., PMID:39964147
Global patterns of amyloid typing: results of a survey by the International Society of Amyloidosis (ISA)., PMID:39928315
Gelsolin traps ribosomal protein SA (RPSA) within lipid nanodomains of the plasma membrane and modulates the level of protein synthesis in the submembranous region of human skin melanoma cells., PMID:39842520
4D-DIA Proteomics Uncovers New Insights into Host Salivary Response Following SARS-CoV-2 Omicron Infection., PMID:39803891
Suppressing the progression of bladder cancer using cyclovirobuxine D based on network pharmacology and bioinformatics approaches., PMID:39797986
The Proteomic Landscape of the Coronary Accessible Heart Cell Surfaceome., PMID:39790063
Persistence of spike protein at the skull-meninges-brain axis may contribute to the neurological sequelae of COVID-19., PMID:39615487
Serum proteome profiling reveals HGFA as a candidate biomarker for pulmonary arterial hypertension., PMID:39609799
Embryonic Temperature Influences the Mucosal Responses of Atlantic Salmon Alevins to a Bacterial Challenge., PMID:39560796
Imetelstat, a novel, first-in-class telomerase inhibitor: Mechanism of action, clinical, and translational science., PMID:39555853
Deciphering Proteomic Expression in Inflammatory Disorders: A Mass Spectrometry Exploration Comparing Infectious, Noninfectious, and Traumatic Brain Injuries in Human Cerebrospinal Fluid., PMID:39391051
Biomarkers and pathways in autism spectrum disorder: An individual meta-analysis based on proteomic and metabolomic data., PMID:39361099
Real-time analysis of the biomolecular interaction between gelsolin and Aβ1-42 monomer and its implication for Alzheimer's disease., PMID:39357407
Interpretable machine learning uncovers epithelial transcriptional rewiring and a role for Gelsolin in COPD., PMID:39352744
Gelsolin controls the release of phosphatidylserine (PS)-positive microvesicles (MVs) from platelets., PMID:39321905
Poly-GP accumulation due to C9orf72 loss of function induces motor neuron apoptosis through autophagy and mitophagy defects., PMID:39316747
Proteomics of left ventricular structure in the Multi-Ethnic Study of Atherosclerosis., PMID:39263947
Decreased plasma gelsolin fosters a fibrotic tumor microenvironment and promotes chemoradiotherapy resistance in esophageal squamous cell carcinoma., PMID:39261905
GFAP and NfL as fluid biomarkers for clinical disease severity and disease progression in multiple system atrophy (MSA)., PMID:39254698
Crotonylation of NAE1 Modulates Cardiac Hypertrophy via Gelsolin Neddylation., PMID:39229723
Enhancing Maturation and Translatability of Human Pluripotent Stem Cell-Derived Cardiomyocytes through a Novel Medium Containing Acetyl-CoA Carboxylase 2 Inhibitor., PMID:39195229
Gelsolin alleviates rheumatoid arthritis by negatively regulating NLRP3 inflammasome activation., PMID:39179640
Response to chronic sustained hypoxia: increased cytosolic gelsolin and decreased plasma gelsolin levels., PMID:39172327
Remote Neuroinflammation in Newly Diagnosed Glioblastoma Correlates with Unfavorable Clinical Outcome., PMID:39150564
The therapeutic potential of gelsolin in attenuating cytokine storm, ARDS, and ALI in severe COVID-19., PMID:39130641
Exploring Canine Mammary Cancer through Liquid Biopsy: Proteomic Profiling of Small Extracellular Vesicles., PMID:39061201
Rubella virus seropositivity after infection or vaccination as a risk factor for multiple sclerosis., PMID:39023088
Rational correction of pathogenic conformational defects in HTRA1., PMID:39013852
The Alzheimer's disease-linked protease BACE2 cleaves VEGFR3 and modulates its signaling., PMID:38888964
Author Correction: Gel-like inclusions of C-terminal fragments of TDP-43 sequester stalled proteasomes in neurons., PMID:38849674
Specific feature recognition on group specific networks (SFR-GSN): a biomarker identification model for cancer stages., PMID:38846963
Mitochondrial lipidomes are tissue specific - low cholesterol contents relate to UCP1 activity., PMID:38843936
Peripheral expression of brain-penetrant progranulin rescues pathologies in mouse models of frontotemporal lobar degeneration., PMID:38838131
Gelsolin knockdown confers radiosensitivity to glioblastoma cells., PMID:38803199
Gelsolin regulates receptor-mediated and fluid-phase endocytosis in platelets., PMID:38777258
Serum proteome signatures associated with ileal and colonic ulcers in Crohn's disease., PMID:38763457
Proteomics of mouse brain endothelium uncovers dysregulation of vesicular transport pathways during aging., PMID:38519806
Proteomic Analysis Identifies GSN as a Noninvasive Circulating Serum Biomarker for Predicting Early Recurrence of Hepatocellular Carcinoma., PMID:38373391
Serum proteome profiling reveals heparanase as a candidate biomarker for chronic thromboembolic pulmonary hypertension., PMID:38333700
For research use only. Not for human or drug use.
