Catalog No.
YHC22001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
His40-Gly195
Predicted molecular weight
19.59 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P06850
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Corticoliberin, Corticotropin-releasing hormone, CRH, CRF, Corticotropin-releasing factor
Corydalis yanhusuo Polysaccharides regulates HPA-axis mediated microglia activation and inhibits astrocyte A1 transformation to improve depression-like behavior., PMID:40513699
Short-term ingestion of sublethal microcystin levels disrupts stress response in male mice., PMID:40491595
Development and Validation of a Liquid Chromatography High-Resolution Mass Spectrometry Method for Blood Desmopressin Quantification and Its Application in Hemophilia A Patients., PMID:40491319
Atlas of Proteomic signatures of brain structure and its links to brain disorders., PMID:40456753
Corticotropin-Releasing Hormone Stimulates Proopiomelanocortin Transcription via the CaMKK/CaMKIV Pathway in the AtT20 Cell Line., PMID:40453274
A key region of Tau that is able to drive assembly and modulate inhibition by Hydromethylthionine., PMID:40441413
Effects of ammonia exposure on the expression of IL-1β, CRH, and lep-a1 genes in common carp (Cyprinus carpio)., PMID:40437528
Antipyretic Mechanism of Bai Hu Tang on LPS-Induced Fever in Rat: A Network Pharmacology and Metabolomics Analysis., PMID:40430430
Interpretable machine learning leverages proteomics to improve cardiovascular disease risk prediction and biomarker identification., PMID:40389651
Predator odor stress produces sex- and subpopulation-specific increases in alcohol drinking, anxiety-like behavior, and lateral hypothalamic Crh expression., PMID:40374160
[Therapeutic effect of Ziziphi Spinosae Semen extracts on chronic unpredictable mild stress-induced depression and insomnia-like behavior in mice]., PMID:40350874
GLP-1 receptor agonist properties of a chimeric peptide derived by hybridization of Latrodectus αLatrotoxin and Heloderma Exendin-4., PMID:40347985
"Maladaptive stress-coping behavior in CX3CR1-deficient mice: Impact of adolescent stress and alcohol exposure on neuroimmune responses and inflammation"., PMID:40339639
Real-world treatment and outcomes for EGFR WT advanced/metastatic non-squamous non-small cell lung cancer: pooled analysis from project LUMINATE-101., PMID:40338221
Acute Restraint Stress Enhances Prosocial Behavior in Rats via Oxytocin and Fear-Related Circuits., PMID:40302260
Functionally divergent melanocortin receptor subtypes and the HPI axis in sea lamprey., PMID:40232816
Corticotropin-releasing hormone inhibits autophagy by suppressing PTEN to promote apoptosis in dermal papilla cells., PMID:40219757
Disruption of Ephb1 causes reduced hypothalamic CRH and TRH expression and obesity in mice., PMID:40207393
Tirzepatide did not impact metabolic adaptation in people with obesity, but increased fat oxidation., PMID:40203836
Loss of age-accumulated crh-1 circRNAs ameliorate amyloid β-induced toxicity in a C. elegans model for Alzheimer's disease., PMID:40196178
The effect of corticotropin-release hormone on duodenal permeability and immune activation in healthy volunteers in a double-blind placebo-controlled study., PMID:40167262
Effect of acupuncture on serum levels of hypothalamic-pituitary-adrenal axis related hormones and immune factors in rats with allergic rhinitis., PMID:40151122
A pontine center in descending pain control., PMID:40132590
The effects of stress and environmental enrichment on cognitive functions and stress-related gene expressions in the brain of aged rats., PMID:40116421
[Mechanisms by Which Paraventricular Hypothalamic Nucleus Participates in the Acupuncture Treatment of Diseases]., PMID:40109474
Androgen receptors in corticotropin-releasing hormone neurons mediate the sexual dimorphism in restraint-induced thymic atrophy., PMID:40106355
Progesterone receptor-dependent downregulation of MHC class I promotes tumor immune evasion and growth in breast cancer., PMID:40102028
Exploring the influence of wild silks composition on dyeing with turmeric and indigo: Spectroscopic insights., PMID:40096779
Mast cells and corticotropin-releasing hormone receptors in duodenal tissue of children with functional dyspepsia., PMID:40050228
Vaccination against furunculosis and vibriosis as a model of immunization induces transcript cellular stress response in rainbow trout mucosal surfaces., PMID:40010617
Comprehensive phenotypic analysis of multiple gene deletions of α-glucan synthase and Crh-transglycosylase gene families in Aspergillus niger highlighting the versatility of the fungal cell wall., PMID:39991742
Identification of genes involved in energy metabolism in preeclampsia and discovery of early biomarkers., PMID:39967661
Hydromethylthionine sustains truncated tau-dependent inflammation-lowering effects in mouse brain., PMID:39960781
Chemogenetic inhibition of corticotropin releasing hormone neurons in the paraventricular nucleus attenuates traumatic stress-induced deficit of NREM sleep, but not REM sleep in mice., PMID:39957245
Quercetin attenuates cisplatin-induced fatigue through mechanisms associated with the regulation of the HPA axis and MCP-1 signaling., PMID:39949542
Extended amygdala corticotropin-releasing hormone neurons regulate sexually dimorphic changes in pair bond formation following social defeat in prairie voles (Microtus ochrogaster)., PMID:39939823
Transcutaneous auricular vagus nerve stimulation inhibits mental stress-induced cortisol release-Potential implications for inflammatory conditions., PMID:39936474
Challenges in diagnosis and treatment of cushing disease in a 12-year-old boy. Case report., PMID:39932307
Sini decoction alleviates LPS-induced sepsis partly via restoration of metabolic impairments in the hypothalamic-pituitary-adrenal microenvironment., PMID:39922328
Corticotropin-releasing hormone receptor 1 mediates the enhanced locomotor activity and metabolic demands to an acute thermal stress in adult zebrafish., PMID:39915694
Development of a Genetic Test Indicating Increased AVP/V1b Signalling in Patients with Acute Depression., PMID:39880002
Spinal CRH facilitates the micturition reflex via the CRH2 receptor in rats with normal bladder and bladder outlet obstruction., PMID:39875474
Sex-specific alterations in emotional behavior and neurotransmitter systems in LPA1 receptor-deficient mice., PMID:39864586
Revumenib: a new era in acute leukemia treatment., PMID:39863449
Hormone circuit explains why most HPA drugs fail for mood disorders and predicts the few that work., PMID:39849227
Oxytocin levels in response to CRH administration in hypopituitarism and hypothalamic damage: a randomized, crossover, placebo-controlled trial., PMID:39824923
Olutasidenib in combination with azacitidine induces durable complete remissions in patients with relapsed or refractory mIDH1 acute myeloid leukemia: a multicohort open-label phase 1/2 trial., PMID:39819505
Associations between maternal plasma concentrations of corticotrophin releasing hormone and the placental transcriptome., PMID:39755094
The neuroimmune mechanism of pain induced depression in psoriatic arthritis and future directions., PMID:39742638
Case report: Pheochromocytoma-induced pseudo-Cushing's syndrome., PMID:39741882
For research use only. Not for human or drug use.
