Catalog No.
YHC15301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu18-Ser501
Predicted molecular weight
55.61 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P05186
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Alkaline phosphatase liver/bone/kidney isozyme, AP-TNAP, TNSALP, Alkaline phosphatase, tissue-nonspecific isozyme, ALPL
A comparative study of three liquid platelet concentrates on human primary osteoblast activity: an in vitro study., PMID:40465952
Expression of Osteogenic Genes in Dental Pulp and Their Correlations in Patients with Clinically Diagnosed Irreversible Pulpitis., PMID:40464527
Alterations of Alpl and bFGF levels in peripheral tissues after mild traumatic brain injury: implications on sexual differences., PMID:40418394
Markedly discordant hypophosphatasia in a young girl., PMID:40409424
Dentoalveolar defects and impaired alveolar bone healing in a neural crest directed conditional knockout mouse model of hypophosphatasia., PMID:40398628
Experimentally verified flexible molecular docking and dynamic simulation of aptamer with intracellular proteins based on direct DNA 3D structure prediction., PMID:40383336
OTX2 expression contributes progression of gastric cancer in young adults., PMID:40341176
Quercetin-calcium hydroxide scaffolds modulate dental pulp stem cell response in vitro under a simulated inflammatory environment., PMID:40285990
Broad Vitamin B6-Related Metabolic Disturbances in a Zebrafish Model of Hypophosphatasia (TNSALP-Deficiency)., PMID:40244092
Effects of asfotase alfa on fracture healing of adult patient with hypophosphatasia and literature review., PMID:40189581
Selective effects of collagen-derived peptides Pro-Hyp and Hyp-Gly on the proliferation and differentiation of SSEA3-positive human dental pulp stem cells., PMID:40170801
LincRNA-ASAO promotes dental pulp repair through interacting with PTBP1 to increase ALPL alternative splicing., PMID:40140936
Safety and efficacy of long term asfotase alfa treatment in childhood hypophosphatasia., PMID:40114282
Hindlimb Unloading Reversibly Attenuates Osteogenic Potential of Rat Skeletal Stem and Progenitor Cells ex vivo., PMID:40101692
Diagnosis and Treatment of Hypophosphatasia., PMID:40047955
Deficiency of intestinal alkaline phosphatase affects behavior and microglia activity in mice., PMID:39984137
Genetic characterization of a large cohort of individuals with a clinical suspicion of hypophosphatasia in the United States., PMID:39983296
Disease burden by ALPL variant number in patients with non-life-threatening hypophosphatasia in the Global HPP Registry., PMID:39965917
Infantile hypophosphatasia: a rare aetiology of recurrent pneumonia., PMID:39922572
Casein Glycomacropeptide Regulates Gene Expression in Intestinal Epithelial Cells: Effect of Simulated Gastrointestinal Digestion and Peptide Microencapsulation., PMID:39921639
Vdr mediates Wnt signaling pathway to regulate odontoblasts differentiation during dentin apposition., PMID:39894431
Efficacy of asfotase alfa in a patient with adult-onset hypophosphatasia without obvious bone lesions: a case report with review of literature., PMID:39880615
[Artificial light at night effects glucose metabolism in the developing jawbone by inhibiting melatonin secretion]., PMID:39848802
Preclinical evaluation of the efficacy and safety of adeno-associated virus 8-tissue-nonspecific alkaline phosphatase-D10 in Alpl-/- and AlplPrx1/Prx1 mouse models for the treatment of early and late-onset hypophosphatasia., PMID:39799564
CASR, CLDN 14, ALPL & SLC34A1 genes are associated with the risk of nephrolithiasis in Egyptian children., PMID:39788827
A NOTCH3 pathogenic variant influences osteogenesis and can be targeted by antisense oligonucleotides in induced pluripotent stem cells., PMID:39752389
Adult-onset hypophosphatasia diagnosed after consecutive tooth loss during orthodontic treatment: a case report., PMID:39702252
Screening for Hypophosphatasia in Adult Patients at a Maximum Care Provider-Retrospective Analyses over Fifteen Years., PMID:39685776
Polyphenol extract from Tagetes erecta L. flowers stimulates osteogenesis via β-catenin activation., PMID:39675109
Diagnosis, treatment, and follow-up of patients with hypophosphatasia., PMID:39663303
The effect of osteoclasts on epigenetic regulation by long non-coding RNAs in osteoblasts grown on titanium with nanotopography., PMID:39622096
Development and characterization of an in vitro fluorescently tagged 3D bone-cartilage interface model., PMID:39600948
A NOTCH2 pathogenic variant and HES1 regulate osteoclastogenesis in induced pluripotent stem cells., PMID:39571704
Simulated microgravity environment inhibits matrix mineralization during the osteoblast to osteocyte differentiation., PMID:39550861
Elevated glucose levels increase vascular calcification risk by disrupting extracellular pyrophosphate metabolism., PMID:39529124
The Benefits of Whole-Exome Sequencing in the Differential Diagnosis of Hypophosphatasia., PMID:39519277
7-Ketocholesterol Effects on Osteogenic Differentiation of Adipose Tissue-Derived Mesenchymal Stem Cells., PMID:39518932
Possible role of bone turnover markers in the diagnosis of adult hypophosphatasia., PMID:39498489
Genetics of Calcific Aortic Stenosis: A Systematic Review., PMID:39457433
Effects of icariin on dental pulp stem cells and its potential applications in dentin repair., PMID:39437662
Tissue nonspecific alkaline phosphatase deficiency impairs Purkinje cell development and survival in a mouse model of infantile hypophosphatasia., PMID:39369942
Modulation of regenerative responses by retinoic and ascorbic acids in human apical papilla cells., PMID:39357392
Whole genome sequencing in adults with clinical hallmarks of hypophosphatasia negative for ALPL variants., PMID:39276275
Phloridzin functionalized gelatin-based scaffold for bone tissue engineering., PMID:39218179
Rare diseases: a challenge in paediatric dentistry., PMID:39212455
An Insight of Plant Source, Toxicological Profile, and Pharmacological Activities of Iridoid Loganic Acid: A ComprehensiveReview., PMID:39113595
Osteogenic differentiation of bone mesenchymal stem cells on linearly aligned triangular micropatterns., PMID:39093007
Development of a functional beige fat cell line uncovers independent subclasses of cells expressing UCP1 and the futile creatine cycle., PMID:39084217
In vitroosteogenesis of hMSCs on collagen membranes embedded within LEGO®-inspired 3D printed PCL constructs for mandibular bone repair., PMID:39079546
Aspirin Stimulates the Osteogenic Differentiation of Human Adipose Tissue-Derived Stem Cells In Vitro., PMID:39062933
For research use only. Not for human or drug use.
