Catalog No.
YHC13801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Pro415
Predicted molecular weight
48.91 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P05120
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
SERPINB2, Monocyte Arg-serpin, Placental plasminogen activator inhibitor, Urokinase inhibitor, PLANH2, PAI-2, Serpin B2, PAI2, Plasminogen activator inhibitor 2
Transglutaminase 2-mediated glutamine deamidation enhances p21 stability during senescence., PMID:40498452
Antiretroviral Therapy at Conception Leads to Lower Peripheral CD49a+ NK Cells and Higher SERPINB2., PMID:40438469
[Research progress of serine protease inhibitors family in diseases]., PMID:40374365
Integrative Analysis Reveals Genes Causal Relation with Ovarian Cancer and aging., PMID:40353459
Bordetella adenylate cyclase toxin elicits chromatin remodeling and transcriptional reprogramming that blocks differentiation of monocytes into macrophages., PMID:40105369
Identification of biomarkers for the diagnosis of type 2 diabetes mellitus with metabolic associated fatty liver disease by bioinformatics analysis and experimental validation., PMID:39936105
AhR Causes the Release of Proinflammatory Cytokines and Chemokines and Airway Epithelial Barrier Dysfunction in Allergic Rhinitis via Upregulating SERPINB2., PMID:39923755
Deciphering the therapeutic effects of Xiyanping injection: insights into pulmonary and gut microbiome modulation, SerpinB2/PAI-2 targeting, and alleviation of influenza a virus-induced lung injury., PMID:39875956
Regulation of epidermal barrier function and pathogenesis of psoriasis by serine protease inhibitors., PMID:39737188
Serpin Family B Member 2 Polymorphisms in Patients with Diabetic Kidney Disease: An Association Study., PMID:39456691
Unraveling potential gene biomarkers for dengue infection through RNA sequencing., PMID:39397194
Unveiling senescence-associated secretory phenotype in epidermal aging: insights from reversibly immortalized keratinocytes., PMID:39316420
A subset of dopamine receptor-expressing neurons in the nucleus accumbens controls feeding and energy homeostasis., PMID:39147933
SerpinB2 deficiency is associated with delayed mammary tumor development and decreased pro-tumorigenic macrophage polarization., PMID:38956496
Neuroinflammation signatures in dorsal root ganglia following chronic constriction injury., PMID:38813203
Capsaicin enhances cisplatin-induced anti-metastasis of nasopharyngeal carcinoma by inhibiting EMT and ERK signaling via serpin family B member 2., PMID:38756095
Estetrol/GPER/SERPINB2 transduction signaling inhibits the motility of triple-negative breast cancer cells., PMID:38741146
Increased SERPINB2 potentiates 15LO1 expression via STAT6 signalling in epithelial cells in eosinophilic chronic rhinosinusitis with nasal polyps., PMID:38639267
Transcriptional and phenotypical alterations associated with a gradual benzo[a]pyrene-induced transition of human bronchial epithelial cells into mesenchymal-like cells., PMID:38522766
Adipose-derived stem cell exosomes promote tumor characterization and immunosuppressive microenvironment in breast cancer., PMID:38294569
Proteomic analysis of holocarboxylase synthetase deficient-MDA-MB-231 breast cancer cells revealed the biochemical changes associated with cell death, impaired growth signaling, and metabolism., PMID:38283944
Epigallocatechin Gallate Modulates Microglia Phenotype to Suppress Pro-inflammatory Signalling Cues and Inhibit Phagocytosis., PMID:38095777
ID1 expressing macrophages support cancer cell stemness and limit CD8+ T cell infiltration in colorectal cancer., PMID:37996458
Transcriptomic analysis reveals that RasGEF1b deletion alters basal and LPS-induced expression of genes involved in chemotaxis and cytokine responses in macrophages., PMID:37950057
The Association of Different Genetic Variants with the Development of Hypoxic-Ischemic Encephalopathy., PMID:37893168
circPSD3 is a promising inhibitor of uPA system to inhibit vascular invasion and metastasis in hepatocellular carcinoma., PMID:37884951
Immunological profiling in long COVID: overall low grade inflammation and T-lymphocyte senescence and increased monocyte activation correlating with increasing fatigue severity., PMID:37881427
An Andrographis paniculata Burm. Nees extract standardized for three main Andrographolides prevents house dust mite-induced airway inflammation, remodeling, and hyperreactivity by regulating Th1/Th2 gene expression in mice., PMID:37652197
EXTRACELLULAR CIRP INHIBITS NEUTROPHIL APOPTOSIS TO PROMOTE ITS AGING BY UPREGULATING SERPINB2 IN SEPSIS., PMID:37548626
Development and validation of asthma risk prediction models using co-expression gene modules and machine learning methods., PMID:37438356
Bioinformatic Analysis of Key Regulatory Genes in Adult Asthma and Prediction of Potential Drug Candidates., PMID:37241840
MASP2 inhibition by narsoplimab suppresses endotheliopathies characteristic of transplant-associated thrombotic microangiopathy: in vitro and ex vivo evidence., PMID:37191586
Amphiregulin blockade decreases the levodopa-induced dyskinesia in a 6-hydroxydopamine Parkinson's disease mouse model., PMID:37101388
Epithelial CST1 Promotes Airway Eosinophilic Inflammation in Asthma via the AKT Signaling Pathway., PMID:37075800
Macrophage-derived GPNMB trapped by fibrotic extracellular matrix promotes pulmonary fibrosis., PMID:36732560
Therapeutic potential of nanoceria pretreatment in preventing the development of urological chronic pelvic pain syndrome: Immunomodulation via reactive oxygen species scavenging and SerpinB2 downregulation., PMID:36684074
High-Resolution Analysis of Mononuclear Phagocytes Reveals GPNMB as a Prognostic Marker in Human Colorectal Liver Metastasis., PMID:36652202
SERPINB2, an Early Responsive Gene to Epigallocatechin Gallate, Inhibits Migration and Promotes Apoptosis in Esophageal Cancer Cells., PMID:36497110
Screening of potential biomarkers in peripheral blood of patients with depression based on weighted gene co-expression network analysis and machine learning algorithms., PMID:36325528
The role of plasminogen activator inhibitor-2 in pneumococcal meningitis., PMID:36309755
miR-450b promotes cell migration and invasion by inhibiting SERPINB2 in oral squamous cell carcinoma., PMID:36251494
A 9‑gene expression signature to predict stage development in resectable stomach adenocarcinoma., PMID:36241983
Low CC16 mRNA Expression Levels in Bronchial Epithelial Cells Are Associated with Asthma Severity., PMID:36066606
Elevated CXCL14 in Induced Sputum Was Associated with Eosinophilic Inflammation and Airway Obstruction in Patients with Asthma., PMID:36063806
RNA-Seq transcriptome analysis reveals Maackia amurensis leukoagglutinin has antitumor activity in human anaplastic thyroid cancer cells., PMID:36057880
Transcriptomic Analysis of Human Keratinocytes Treated with Galactomyces Ferment Filtrate, a Beneficial Cosmetic Ingredient., PMID:36012891
IL11 Stimulates IL33 Expression and Proinflammatory Fibroblast Activation across Tissues., PMID:36012165
The nuclear receptor TLX (NR2E1) inhibits growth and progression of triple- negative breast cancer., PMID:35932893
MicroRNA-196a-5p overexpression in Wharton's jelly umbilical cord stem cells promotes their osteogenic differentiation and new bone formation in bone defects in the rat calvarium., PMID:35925405
Human IL-17 and TNF-α Additively or Synergistically Regulate the Expression of Proinflammatory Genes, Coagulation-Related Genes, and Tight Junction Genes in Porcine Aortic Endothelial Cells., PMID:35844613
For research use only. Not for human or drug use.
