Catalog No.
YVV29901
Expression system
E. coli
Species
Human metapneumovirus (strain CAN97-83) (HMPV)
Protein length
Thr2-Ser71
Predicted molecular weight
36.24 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q6WB96
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Protein M2-2, M2
The selective autophagic degradation of avian metapneumovirus subgroup C M2-2 protein via SQSTM1 suppresses viral replication., PMID:40395539
The role of M2 proteins of pneumoviruses in transcription regulation, prevention of hypermutation, and activation of the type I interferon pathway., PMID:39835813
Human metapneumovirus M2-2 protein inhibits RIG-I signaling by preventing TRIM25-mediated RIG-I ubiquitination., PMID:36045682
Evidence against the Human Metapneumovirus G, SH, and M2-2 Proteins as Bona Fide Interferon Antagonists., PMID:35975999
Human Metapneumovirus Escapes NK Cell Recognition through the Downregulation of Stress-Induced Ligands for NKG2D., PMID:32698530
The role of M2-2 PDZ-binding motifs in pulmonary innate immune responses to human metapneumovirus., PMID:32073159
Detection of Nuclear Protein Profile Changes by Human Metapneumovirus M2-2 Protein Using Quantitative Differential Proteomics., PMID:29207503
Human Metapneumovirus M2-2 Protein Acts as a Negative Regulator of Alpha Interferon Production by Plasmacytoid Dendritic Cells., PMID:28768858
Functional motifs responsible for human metapneumovirus M2-2-mediated innate immune evasion., PMID:27743962
Genome-Wide Analysis of Human Metapneumovirus Evolution., PMID:27046055
Human metapneumovirus infection induces significant changes in small noncoding RNA expression in airway epithelial cells., PMID:24845106
Human metapneumovirus M2-2 protein inhibits innate immune response in monocyte-derived dendritic cells., PMID:24618691
Human metapneumovirus M2-2 protein inhibits innate cellular signaling by targeting MAVS., PMID:23015697
Human metapneumovirus M2-2 protein inhibits viral transcription and replication., PMID:19913636
Human metapneumovirus nucleoprotein and phosphoprotein interact and provide the minimal requirements for inclusion body formation., PMID:18931065
Deletion of human metapneumovirus M2-2 increases mutation frequency and attenuates growth in hamsters., PMID:18519001
Mapping and characterization of the primary and anamnestic H-2(d)-restricted cytotoxic T-lymphocyte response in mice against human metapneumovirus., PMID:17670840
Live vaccines for human metapneumovirus designed by reverse genetics., PMID:17181442
Infection of nonhuman primates with recombinant human metapneumovirus lacking the SH, G, or M2-2 protein categorizes each as a nonessential accessory protein and identifies vaccine candidates., PMID:16160190
Deletion of M2 gene open reading frames 1 and 2 of human metapneumovirus: effects on RNA synthesis, attenuation, and immunogenicity., PMID:15890897
High genetic diversity of the attachment (G) protein of human metapneumovirus., PMID:15297475
Subtype B avian metapneumovirus resembles subtype A more closely than subtype C or human metapneumovirus with respect to the phosphoprotein, and second matrix and small hydrophobic proteins., PMID:12686426
Analysis of the genomic sequence of a human metapneumovirus., PMID:12033771
For research use only. Not for human or drug use.
