Catalog No.
VHC97901
Species reactivity
Human
Host species
Human
Isotype
IgG1, kappa
Clonality
Monoclonal
Target
TCP228, C-C motif chemokine 5, CCL5, T cell-specific protein P228, D17S136E, Small-inducible cytokine A5, SIS-delta, SCYA5, T-cell-specific protein RANTES, Eosinophil chemotactic cytokine, EoCP
Concentration
0.87 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P13501
Applications
ELISA, Neutralization
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
Iv0079
Immune-related gene risk model establishment and role of key gene FUCA1 in malignant pleural mesothelioma., PMID:40487392
The role of immune checkpoint molecules in PRRSV-2-induced immune modulation: insights from comparative in vivo evaluation including NADC34-like PRRSV., PMID:40459260
Mesangial angiogenesis and interstitial eosinophilic infiltration in diabetic nephropathy are associated with elevated CD248 expression., PMID:40451785
3,4-Dihydroxybenzoic acid methyl ester from Vespa velutina auraria Smith against rheumatoid arthritis via modulating the apoptosis and inflammation through NF-κB pathway., PMID:40448819
Unleashing anti-tumor immunity: Targeting the autophagy-related protein VPS34 to enhance STING agonist-based therapy., PMID:40395527
CCR5-Mediated Reprogramming of Regulatory T Cells and Monocytic-Myeloid-Derived Suppressor Cells in Young Dyslipidemic Individuals: A Plausible Therapeutic Approach., PMID:40387394
Tumor-derived exosomal CCT6A serves as a matchmaker introducing chemokines to tumor-associated macrophages in pancreatic ductal adenocarcinoma., PMID:40374617
Selective BCL-2 inhibitor triggers STING-dependent antitumor immunity via inducing mtDNA release., PMID:40300857
Investigating shared diagnostic genes and mechanisms between metabolic syndrome and dry eye disease via integrated bioinformatics analysis and in vivo validation., PMID:40280534
Injectable cellular vesicle-based bone meal for inflammatory bone defect repair through restoring immune homeostasis., PMID:40225579
Decreased CCL5 expression in endometrial stromal cells induces deficient CCR5 +CD4 + T cells in endometriosis., PMID:40205945
APOC1 expressed in macrophages promotes the pulmonary metastasis of colorectal cancer via CCL2/CCL5., PMID:40194454
scRNA-seq of the intestine reveals the key role of mast cells in early gut dysfunction associated with acute pancreatitis., PMID:40182603
Harnessing immunotherapeutic molecules and diagnostic biomarkers as human-derived adjuvants for MERS-CoV vaccine development., PMID:40181980
Role of Quercetin in Modulating Inflammation and Epigenetic Regulation of Staphylococcus aureus-Induced Bovine Mastitis., PMID:40168353
Axl Regulation of NK Cell Activity Creates an Immunosuppressive Tumor Immune Microenvironment in Head and Neck Cancer., PMID:40149328
Altered cytokine release of airway epithelial cells in vitro by combinations of respiratory syncytial virus, Streptococcus pneumoniae, Printex 90 and diesel exhaust particles., PMID:40118319
SCM-198 Inhibits EMS Development by Reversing Decreased Proportions of IFN-γ+T Cells and CCR5+T Cells., PMID:40113654
PBRM1 deficiency enhances PD1 immunotherapeutic sensitivity via chromosomal accessibility in colorectal cancer., PMID:40093909
Genetic deletion of G protein-coupled receptor 56 aggravates traumatic brain injury through the microglial CCL3/4/5 upregulation targeted to CCR5., PMID:40089481
Selective Depletion of CCR8+Treg Cells Enhances the Antitumor Immunity of Cytotoxic T Cells in Lung Cancer by Dendritic Cells., PMID:40056978
Aged regulatory T cells fail to control autoimmune lacrimal gland pathogenic CD4+ T cells., PMID:40053297
EGCG inhibits tobacco smoke-promoted proliferation of lung cancer cells through targeting CCL5., PMID:40010030
NOX4 modulates breast cancer progression through cancer cell metabolic reprogramming and CD8+ T cell antitumor activity., PMID:39991149
Rutecarpine Suppresses Non-Small Cell Lung Cancer Progression Through Activating the STING Pathway and Elevating CD8+ T Cells., PMID:39989173
MSCs act as biopatches for blood-retinal barrier preservation to enhance functional recovery after retinal I/R., PMID:39967853
Corydalis Tuber Extract Alleviates Atopic Dermatitis: Transcriptomics-Based Mechanism Prediction and In Vitro/In Vivo Studies., PMID:39941059
Clofarabine induces tumor cell apoptosis, GSDME-related pyroptosis, and CD8+ T-cell antitumor activity via the non-canonical P53/STING pathway., PMID:39915005
Targeted editing of CCL5 with CRISPR-Cas9 nanoparticles enhances breast cancer immunotherapy., PMID:39870938
Pseudostellaria heterophylla (Miq.) Pax, a traditional folk medicine, ameliorates colorectal cancer by remodeling the tumor immune microenvironment., PMID:39828144
Sinensetin attenuates LPS-induced acute pulmonary inflammation in mice and RAW264.7 cells by modulating NF-κB p65-mediated immune resistance and STAT3-mediated tissue resilience., PMID:39827664
Topical Anti-Inflammatory Effects of Quercetin Glycosides on Atopic Dermatitis-Like Lesions: Influence of the Glycone Type on Efficacy and Skin Absorption., PMID:39808370
Novel full-thickness biomimetic corneal model for studying pathogenesis and treatment of diabetic keratopathy., PMID:39807180
Blocking the CCL5/CCL7-CCR1 axis regulates macrophage polarization through NF-κB pathway to alleviate the progression of osteoarthritis., PMID:39805173
5β-hydroxycostic acid from Laggera alata ameliorates sepsis-associated acute kidney injury through its anti-inflammatory and anti-ferroptosis effects via NF-κB and MAPK pathways., PMID:39800248
Integration of transcriptomics and metabolomics reveals the mechanism of Glycyrrhizae Radix Et Rhizoma extract inhibiting CCL5 in the treatment of acute pharyngitis., PMID:39798344
CCR5 and IL-12 co-expression in CAR T cells improves antitumor efficacy by reprogramming tumor microenvironment in solid tumors., PMID:39751840
C-C motif chemokine ligand 5 contributes to radon exposure-induced lung injury by recruiting dendritic cells to activate effector T helper cells., PMID:39746565
Lycorine Suppresses Non-Small-Cell Lung Cancer Progression Through Activating STING Pathway and Stimulating an Antitumor Immune Response., PMID:39707625
Membrane palmitoylated protein MPP1 inhibits immune escape by regulating the USP12/ CCL5 axis in urothelial carcinoma., PMID:39700963
Alterations of the IKZF1-IKZF2 tandem in immune cells of schizophrenia patients regulate associated phenotypes., PMID:39695786
IL-1ra and CCL5, but not IL-10, are promising targets for treating SMA astrocyte-driven pathology., PMID:39673131
Tissue factor promotes TREX1 protein stability to evade cGAS-STING innate immune response in pancreatic ductal adenocarcinoma., PMID:39658648
IL-23R is a senescence-linked circulating and tissue biomarker of aging., PMID:39658621
The CCL5/CCR5/SHP2 axis sustains Stat1 phosphorylation and activates NF-κB signaling promoting M1 macrophage polarization and exacerbating chronic prostatic inflammation., PMID:39633456
Targeting CCL5 Attenuates Fibrosis via Activation of PI3k/Akt Signaling Axis After Glaucoma Filtration Surgery., PMID:39618346
Cilomilast Modulates Rhinovirus-Induced Airway Epithelial ICAM-1 Expression and IL-6, CXCL8 and CCL5 Production., PMID:39598462
Remolding the tumor microenvironment by bacteria augments adoptive T cell therapy in advanced-stage solid tumors., PMID:39572541
Non-redundant roles of the CCR1 and CCR2 chemokine axes in monocyte recruitment during lung metastasis., PMID:39566333
Procaine Regulates the STAT3/CCL5 Axis and Inhibits Microglia M1 Polarization to Alleviate Complete Freund's Adjuvant Rats Pain Behavior., PMID:39542733
For research use only. Not for human or drug use.
