Catalog No.
PHB77501
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human SNAI1 (Met1-Arg264).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Protein sna,SNAI1,Zinc finger protein SNAI1,Protein snail homolog 1,SNAH
Purification
Purified by antigen affinity column.
Accession
O95863
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Is epithelial-mesenchymal transition related to the biological behavior of salivary gland neoplasms?, PMID:38852529
Molecular Signatures in Swine Innate and Adaptive Immune Responses to African Swine Fever Virus Antigens p30/p54/CD2v Expressed Using a Highly Efficient Semliki Forest Virus Replicon System., PMID:37298266
Targeting endogenous kidney regeneration using anti-IL11 therapy in acute and chronic models of kidney disease., PMID:36470928
IL11 stimulates ERK/P90RSK to inhibit LKB1/AMPK and activate mTOR initiating a mesenchymal program in stromal, epithelial, and cancer cells., PMID:35992082
SNAI1-expressing fibroblasts and derived-extracellular matrix as mediators of drug resistance in colorectal cancer patients., PMID:35878797
LATS kinases and SLUG regulate the transition to advanced stage in aggressive oral cancer cells., PMID:35859006
Immunohistochemical expression of E-cadherin, N-cadherin and Snail/slug in ameloblastoma., PMID:35659530
[Effect and mechanism of TNF-α and etanercept on the invasion ability of extravillous trophoblast cell in URSA patients]., PMID:34823320
Cellular junction and mesenchymal factors delineate an endometriosis-specific response of endometrial stromal cells to the mesothelium., PMID:34624439
COL10A1 is a novel factor in the development of choroidal neovascularization., PMID:34520774
Analysis of Several Pathways for Efficient Killing of Prostate Cancer Stem Cells: A Central Role of NF-κB RELA., PMID:34445612
PD-L1 tumor-intrinsic signaling and its therapeutic implication in triple-negative breast cancer., PMID:33884962
TGF-β activates pericytes via induction of the epithelial-to-mesenchymal transition protein SLUG in glioblastoma., PMID:33780024
Three and Four-Dimensional Visualization and Analysis Approaches to Study Vertebrate Axial Elongation and Segmentation., PMID:33720141
Radiation exposure triggers the malignancy of non‑small cell lung cancer cells through the activation of visfatin/Snail signaling., PMID:33432364
Molecular phenotypes of circulating tumor cells and efficacy of nivolumab treatment in patients with head and neck squamous cell carcinoma., PMID:33299117
RAC1B Regulation of TGFB1 Reveals an Unexpected Role of Autocrine TGFβ1 in the Suppression of Cell Motility., PMID:33260366
KIF3C Promotes Proliferation, Migration, and Invasion of Glioma Cells by Activating the PI3K/AKT Pathway and Inducing EMT., PMID:33150178
CBP-mediated Slug acetylation stabilizes Slug and promotes EMT and migration of breast cancer cells., PMID:32737855
Circular RNA circMET drives immunosuppression and anti-PD1 therapy resistance in hepatocellular carcinoma via the miR-30-5p/snail/DPP4 axis., PMID:32430013
LOXL2 upregulates hypoxia‑inducible factor‑1α signaling through Snail‑FBP1 axis in hepatocellular carcinoma cells., PMID:32323822
Robust induction of neural crest cells to derive peripheral sensory neurons from human induced pluripotent stem cells., PMID:32152328
Direct Extracellular NAMPT Involvement in Pulmonary Hypertension and Vascular Remodeling. Transcriptional Regulation by SOX and HIF-2α., PMID:32142369
SNAIL expression correlates with the translocation of syndecan‑1 intracellular domain into the nucleus in prostate cancer cell lines., PMID:32124938
SEMA4C is a novel target to limit osteosarcoma growth, progression, and metastasis., PMID:31582836
C/EBPδ-Slug-Lox1 axis promotes metastasis of lung adenocarcinoma via oxLDL uptake., PMID:31562393
ANKHD1 is required for SMYD3 to promote tumor metastasis in hepatocellular carcinoma., PMID:30646949
Epithelial to Mesenchymal Transition in Human Mesothelial Cells Exposed to Asbestos Fibers: Role of TGF-β as Mediator of Malignant Mesothelioma Development or Metastasis via EMT Event., PMID:30609805
Annexin A1-suppressed autophagy promotes nasopharyngeal carcinoma cell invasion and metastasis by PI3K/AKT signaling activation., PMID:30459351
DSG2 Is a Functional Cell Surface Marker for Identification and Isolation of Human Pluripotent Stem Cells., PMID:29910125
CD47 is a direct target of SNAI1 and ZEB1 and its blockade activates the phagocytosis of breast cancer cells undergoing EMT., PMID:29632713
Role of Corneal Stromal Cells on Epithelial Cell Function during Wound Healing., PMID:29401709
Differential expression profiles of conserved Snail transcription factors in the mouse testis., PMID:29381885
The Interplay Between Epithelial-Mesenchymal Transition (EMT) and the Thyroid Hormones-αvβ3 Axis in Ovarian Cancer., PMID:29260382
Neutrophils and Snail Orchestrate the Establishment of a Pro-tumor Microenvironment in Lung Cancer., PMID:29241546
Expression of Epithelial-Mesenchymal Transition Regulating Transcription Factors in Head and Neck Squamous Cell Carcinomas., PMID:28982853
MDM2 promotes epithelial-mesenchymal transition and metastasis of ovarian cancer SKOV3 cells., PMID:28817834
Hybrid clone cells derived from human breast epithelial cells and human breast cancer cells exhibit properties of cancer stem/initiating cells., PMID:28768501
Nimotuzumab Inhibits Cholangiocarcinoma Cell Metastasis via Suppression of the Epithelial-Mesenchymal Transition Process., PMID:28668850
Poly I:C induces collective migration of HaCaT keratinocytes via IL-8., PMID:28438134
Snail acetylation by histone acetyltransferase p300 in lung cancer., PMID:28296173
Identification of Antibody Against SNRPB, Small Nuclear Ribonucleoprotein-Associated Proteins B and B', as an Autoantibody Marker in Crohn's Disease using an Immunoproteomics Approach., PMID:28204086
The immune checkpoint ligand PD-L1 is upregulated in EMT-activated human breast cancer cells by a mechanism involving ZEB-1 and miR-200., PMID:28197390
Differential expression of the epithelial mesenchymal transition factors Snail, Slug, Twist, TGF-β, and E-cadherin in ameloblastoma., PMID:27995335
Action of SNAIL1 in Cardiac Myofibroblasts Is Important for Cardiac Fibrosis following Hypoxic Injury., PMID:27706205
Multi-walled carbon nanotubes directly induce epithelial-mesenchymal transition in human bronchial epithelial cells via the TGF-β-mediated Akt/GSK-3β/SNAIL-1 signalling pathway., PMID:27251132
Targeting TYRO3 inhibits epithelial-mesenchymal transition and increases drug sensitivity in colon cancer., PMID:27132510
Gastrulation EMT Is Independent of P-Cadherin Downregulation., PMID:27097030
The histone variant H2A.X is a regulator of the epithelial-mesenchymal transition., PMID:26876487
Expression of the Long Non-Coding RNA HOTAIR Correlates with Disease Progression in Bladder Cancer and Is Contained in Bladder Cancer Patient Urinary Exosomes., PMID:26800519