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Research Grade Infliximab

Catalog #:   DHB94403 Specific References (50) DATASHEET
Host species: Chimeric
Isotype: IgG1, kappa
Applications: Research Grade Biosimilar
Expression system: Mammalian Cells
Overview

Catalog No.

DHB94403

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Chimeric

Isotype

IgG1, kappa

Clonality

Monoclonal

Applications

Research Grade Biosimilar

Target

TNF, Tumor necrosis factor ligand superfamily member 2, N-terminal fragment, ICD2, NTF, TNF-a, TNF-alpha, Tumor necrosis factor, TNFSF2, TNFA, Cachectin, ICD1

Concentration

1.2 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P01375

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

TA-650, cA2, CAS: 170277-31-3

Clone ID

Infliximab

Note

For research use only. Not suitable for clinical or therapeutic use.

Data Image
  • Bioactivity
    Detects Human TNFa/TNF-alpha in indirect ELISAs.
  • SDS-PAGE
    SDS PAGE for Infliximab
  • SEC-HPLC
    The purity of this product is >95% as determined by SEC-HPLC.
References

Long-Term Response Durability of Infliximab for Pediatric Inflammatory Bowel Disease in Japan: A Single Center Experience., PMID:40396153

Immunomodulatory Therapy Discontinuation for Reasons Other Than Efficacy in the Treatment of Ocular Inflammation., PMID:40397798

PErsistence and safety of subcutaneous infliximab 1 year after switch from intravenous route in IBD patients in REMission., PMID:40398832

The Incidence and Management of TNF-α Inhibitor Induced Paradoxical Psoriasis in Children With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis., PMID:40400050

Effects of infliximab infusion on clinical symptom scores and serum cytokines in patients with inflammatory bowel disease., PMID:40400059

Ustekinumab in the Treatment of Crohn's Disease-A Narrative Review on Clinical Efficacy and Safety Profile., PMID:40407511

Network Meta-Analysis: Efficacy of Biological Therapies and Small Molecules as Maintenance Therapy in Ulcerative Colitis., PMID:40407729

Case report: Spontaneous splenic rupture concomitant with serum sickness induced by infliximab., PMID:40410001

Skin lesions and chest pain in a patient with Crohn's disease., PMID:40413034

A 30-year experience in neuro-Behçet disease., PMID:40414042

Exploring infliximab serum level variability in inflammatory bowel disease: Comprehensive analysis of patient subgroups and treatment outcomes "Infliximab trough levels variability in inflammatory bowel disease"., PMID:40414284

Association of the TNFRSF1B-rs1061622 variant with nonresponse to infliximab in ulcerative colitis., PMID:40414945

The position of anti-Tumor Necrosis Factor agents for the treatment of adult patients with Crohn's disease., PMID:40418234

Comparative efficacy, safety and immunogenicity of biosimilars and their reference biologic drugs in ankylosing spondylitis: a systematic review and meta-analysis of randomized controlled trials., PMID:40418343

Predictors of drug survival of biologics in hidradenitis suppurativa: A systematic review and meta-analysis., PMID:40419221

Efficacy and safety of dual-targeted therapy for refractory inflammatory bowel disease: a retrospective case series from three tertiary general hospitals in China., PMID:40421289

Obinutuzumab-Induced Inflammatory Bowel Disease-Like Colitis., PMID:40421460

Infliximab Biosimilar Utilization in a Large Pediatric Learning Health System., PMID:40426835

The Effects of the Biological Agents Infliximab, Vedolizumab, and Ustekinumab on Intestinal Anastomosis: An Experimental Study in Rats., PMID:40426907

Optimizing Biologic Therapy for the Prevention of Post-Operative Recurrence in Crohn's Disease: Current Evidence and Future Perspectives., PMID:40427059

JAK-STAT inhibitors in noninfectious uveitis - A review., PMID:40434456

Peripheral neuropathies associated with anti-tnf-α treatments: a systematic review and proposed recommendations., PMID:40447953

Treatment of Autoimmune Enteropathy With Vedolizumab., PMID:40452653

Higher induction and maintenance infliximab trough levels are associated with radiological perianal fistula healing in pediatric patients with Crohn's disease., PMID:40453222

Switching from intravenous to subcutaneous infliximab in patients with immune mediated diseases in clinical remission., PMID:40454138

Machine Learning Modeling for Predicting Infliximab Pharmacokinetics in Pediatric and Young Adult Patients With Crohn Disease: Leveraging Ensemble Modeling With Synthetic and Real-World Data., PMID:40459932

Comment on a Risk Stratification Tool for Relapse After Intravenous-to-Subcutaneous Switching of Infliximab in Patients With Inflammatory Bowel Diseases., PMID:40464796

Infliximab-Induced Immune Thrombocytopenic Purpura in an Ulcerative Colitis Patient., PMID:40469247

Pharmacogenomics of TNF inhibitors., PMID:40469293

Anti-tumor Necrosis Factor-Alpha (TNF-α)-Induced Hypertrophic Lichen Planus: A Case Report., PMID:40470457

Tumor necrosis factor α inhibitor-induced alopecia in pediatric patients: a cohort of 20 patients and review of the literature., PMID:40481366

Treatment sequences, outcomes, healthcare utilization, and costs in patients with inflammatory bowel diseases requiring advanced treatment-real world comparative effectiveness from German claims data., PMID:40481399

Pretransplant natural antibody levels identify a subset of deceased donor kidney transplant recipients that benefit from infliximab induction., PMID:40484132

Clinical spectrum of acute severe ulcerative colitis in the biologic era: a prospective cohort study from India., PMID:40485102

Drug survival, long-term safety and efficacy of anti-TNF-alpha biosimilars: a monocentric retrospective study., PMID:40485573

Efficacy and Safety of Vedolizumab with Glucocorticoids vs Infliximabin Severe Ulcerative Colitis: A Retrospective Study., PMID:40487981

Infliximab Pharmacokinetics, Dosing, and Response in Hospitalized Patients with COVID-19 Pneumonia: A Secondary Analysis of a Multinational Randomized Clinical Trial (ACTIV-1 IM)., PMID:40488513

Metabolism and Response to Stress Gene Signatures Reveal Ulcerative Colitis Heterogeneity and Identify Patients With Increased Response to Therapy., PMID:40488582

Bibliometric analysis of global research trends on ultrasound in inflammatory bowel disease: A quickly developing field., PMID:40489862

Development of thymoma without myasthenia gravis in a patient with radiographic axial spondyloarthritis treated with tumor necrosis factor-α inhibitors., PMID:40491307

Clinical characteristics and treatment of infantile Takayasu arteritis in the Chinese Han population: a single-center study., PMID:40495185

Upadacitinib for refractory Behçet's disease with myelodysplastic syndrome and trisomy 8/9: a case report and mechanistic insights., PMID:40496858

The Use of Intravenous Infliximab to Treat Cancer Related Fistulae: A Case Report in Home-Based Palliative Care Improving Quality of Life and Closure., PMID:40498467

Which first? Surgery or biologic therapy for ileocolic Crohn's disease in the real world., PMID:40498697

Comparative effectiveness of ustekinumab versus infliximab in the management of perianal fistulizing Crohn's disease: a retrospective study in China., PMID:40499579

Serial 18F-Fluorodeoxyglucose Positron Emission Tomography to Assess the Efficacy of Infliximab in Steroid Refractory Cardiac Sarcoidosis., PMID:40499889

Curcumin-QingDai Combination as Treatment for Crohn's Disease: A Case Report., PMID:40503450

Post-traumatic ileal stenosis: a rare entity not to be confused with Crohn's disease., PMID:40503976

Effectiveness and Safety of Advanced Dual-Targeted Therapy in Refractory Perianal Crohn's Disease., PMID:40504122

Magnetic resonance spectroscopy biomarkers of anti-inflammatory interventions in mood disorders: A systematic review of clinical trials., PMID:40505984

Datasheet

Document Download

Research Grade Infliximab.pdf

 

$ 280
Product specifications
1 mg 280 5 mg 840 25 mg 2350

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Research Grade Infliximab [DHB94403]
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