Catalog No.
EHE43701
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
His22-His340
Predicted molecular weight
63.53 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P43629
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
HLA-BW4-specific inhibitory NK cell receptor, NKB1, KIR3DL1, p70 NK receptor CL-2/CL-11, CD158E, MHC class I NK cell receptor, Killer cell immunoglobulin-like receptor 3DL1, p70 natural killer cell receptor clones CL-2/CL-11, Natural killer-associated transcript 3, NKAT-3, CD158e, CD158 antigen-like family member E, NKAT3
Peptide selectivity of killer cell immunoglobulin-like receptors differs with allotypic variation in HLA class I., PMID:40127639
Recognition of Novel KIR2DL1*0040135, KIR2DL1*112, KIR2DL1*0040136, KIR3DL1*0010122 Alleles From India., PMID:39721044
An archaic HLA class I receptor allele diversifies natural killer cell-driven immunity in First Nations peoples of Oceania., PMID:39476840
Characterisation of novel KIR alleles: KIR3DL3*0070105, KIR3DL3*0130202, KIR3DL1*0080104 and KIR3DL1*0010121., PMID:39291308
Genetic complexity of killer-cell immunoglobulin-like receptor genes in human pangenome assemblies., PMID:39251346
Identification of four novel KIR alleles in haematopoietic stem cell donors of Indian origin., PMID:39162080
Validation of KIR3DL1 alleles assigned by next generation sequencing., PMID:39022874
Oncogenic alterations in KIR3DL1 in cutaneous acral CD8+ lymphoproliferative disorder., PMID:38924750
Multifactorial determinants of NK cell repertoire organization: insights into age, sex, KIR genotype, HLA typing, and CMV influence., PMID:38736873
Polymorphic residues in HLA-B that mediate HIV control distinctly modulate peptide interactions with both TCR and KIR molecules., PMID:38733995
Evaluation of KIR3DL1/KIR3DS1 allelic polymorphisms in Kenyan children with endemic Burkitt lymphoma., PMID:37647275
Establishing NK-Cell Receptor Restriction by Flow Cytometry and Detecting Potential NK-Cell Clones of Uncertain Significance., PMID:37385341
Expression profile of KIR3DS1/KIR3DL1 receptors in association with immunological responses in TB, HIV and HIV/TB infected patients., PMID:37169313
HLA-Bw4 in association with KIR3DL1 favors natural killer cell-mediated protection against severe COVID-19., PMID:36849422
Identification of the novel KIR3DL1*00703 allele in a Chinese Han individual., PMID:36258300
Characterization of the novel KIR3DL1*01507 allele identified in a Chinese Han individual., PMID:36254745
Allele imputation for the killer cell immunoglobulin-like receptor KIR3DL1/S1., PMID:35192601
Expression of Killer Immunoglobulin Receptor Genes among HIV-Infected Individuals with Non-AIDS Comorbidities., PMID:35071606
Donor NK and T Cells in the Periphery of Lung Transplant Recipients Contain High Frequencies of Killer Cell Immunoglobulin-Like Receptor-Positive Subsets., PMID:34966390
ERAP1 Controls the Interaction of the Inhibitory Receptor KIR3DL1 With HLA-B51:01 by Affecting Natural Killer Cell Function., PMID:34917091
Association analysis of KIR/HLA genotype with liver cirrhosis, hepatocellular carcinoma, and NUC freedom in chronic hepatitis B patients., PMID:34728722
KIR3DL1 Allotype-Dependent Modulation of NK Cell Immunity against Chronic Myeloid Leukemia., PMID:34433624
NK Cell Responses in Zika Virus Infection Are Biased towards Cytokine-Mediated Effector Functions., PMID:34408012
Immunomonitoring of Stage IV Relapsed Neuroblastoma Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplantation and Subsequent GD2 (ch14.18/CHO) Antibody Treatment., PMID:34367149
Identification of the novel KIR3DL1*00702 allele in a Northern Chinese Han individual., PMID:34219402
Natural Killer Cells Generated From Human Induced Pluripotent Stem Cells Mature to CD56brightCD16+NKp80+/-In-Vitro and Express KIR2DL2/DL3 and KIR3DL1., PMID:34017328
The Role of the HLA Class I α2 Helix in Determining Ligand Hierarchy for the Killer Cell Ig-like Receptor 3DL1., PMID:33441440
Altered oxidative stress markers in relation to T cells, NK cells & killer immunoglobulin receptors that are associated with disease activity in SLE patients., PMID:32998620
Association of killer-cell immunoglobulin-like receptor genes with acute myelogenous leukaemia., PMID:32767509
Killer Cell Immunoglobulin-like Receptor Variants Are Associated with Protection from Symptoms Associated with More Severe Course in Parkinson Disease., PMID:32709660
KIR3DL1 and HLA-Bw4 Interaction Showed a Favorable Role in Patients with Myelodysplastic Syndromes in Chinese Southern Han., PMID:32420357
Phenotypic and functional characterization of natural killer cells in rheumatoid arthritis-regulation with interleukin-15., PMID:32246007
External validation of models for KIR2DS1/KIR3DL1-informed selection of hematopoietic cell donors fails., PMID:31932846
Reconstitution of NK cells expressing KIR3DL1 is associated with reduced NK cell activity and relapse of CML after allogeneic hematopoietic stem cell transplantation., PMID:31873846
Association of Functional Polymorphisms of KIR3DL1/DS1 With Behçet's Disease., PMID:31849952
In vitro education of human natural killer cells by KIR3DL1., PMID:31723004
[A protective effect conferred by KIR3DL1 and its cognate ligand against cervical cancer among ethnic Han Chinese population and its potential mechanism]., PMID:31598955
The Education of NK Cells Determines Their Responsiveness to Autologous HIV-Infected CD4 T Cells., PMID:31511383
KIR3DL1/S1 Allotypes Contribute Differentially to the Development of Behçet Disease., PMID:31405953
Decreased interferon-γ production by NK cells from KIR haplotype B carriers in hepatitis C virus infection., PMID:31177636
Characterization of the novel KIR3DL3*062 allele identified in a Southern Chinese Han individual., PMID:30945449
Identification of the novel KIR3DL3*02602 allele from a southern Chinese Han individual., PMID:30941923
Description of the novel KIR3DL3*063 allele identified in a Southern Chinese Han individual., PMID:30941914
Characterization of the novel KIR3DL1*0150213 and KIR3DL1*112 alleles using sequence-based typing., PMID:30884129
Follicular lymphoma patients with KIR2DL2 and KIR3DL1 and their ligands (HLA-C1 and HLA-Bw4) show improved outcome when receiving rituximab., PMID:30871628
Conformational Changes in the Cytoplasmic Region of KIR3DL1 upon Interaction with SHP-2., PMID:30773397
Differential contribution of education through KIR2DL1, KIR2DL3, and KIR3DL1 to antibody-dependent (AD) NK cell activation and ADCC., PMID:30698860
A child with perinatal HIV infection and long-term sustained virological control following antiretroviral treatment cessation., PMID:30679439
Identification of two novel KIR3DL1 subtypes, KIR3DL1*0010104 and KIR3DL1*0010105., PMID:30582293
Autoantibodies to killer cell immunoglobulin-like receptor 3DL1 in patients with systemic lupus erythematosus., PMID:30421793
For research use only. Not for human or drug use.
