Catalog No.
EHD58801
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Gln51-Leu183
Predicted molecular weight
43.26 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P23510
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CD252, OX40L, TXGP1, OX40 ligand, Glycoprotein Gp34, TAX transcriptionally-activated glycoprotein 1, TNFSF4, Tumor necrosis factor ligand superfamily member 4
Association between OX40L rs1234314 and rs844648 polymorphisms and unexplained recurrent pregnancy loss., PMID:40465113
OX40-OX40L Axis in Cutaneous T-Cell Lymphomas: Pathogenic, Prognostic, and Potential Therapeutic Perspectives., PMID:40427608
Identifying TNFSF4low-MSCs superiorly treating idiopathic pulmonary fibrosis through Tregs differentiation modulation., PMID:40254578
Activation of immune checkpoint OX40 inhibits HBV replication in a mouse model., PMID:39923582
MiR-125b-5p ameliorates ox-LDL-induced vascular endothelial cell dysfunction by negatively regulating TNFSF4/TLR4/NF-κB signaling., PMID:39856662
Pan-cancer analysis shows that TNFSF4 is a potential prognostic and immunotherapeutic biomarker for multiple cancer types including liver cancer., PMID:39825223
Comparison of CD30L and OX40L Reveals CD30L as a Promising Therapeutic Target in Atopic Dermatitis., PMID:39589186
CAR-ving away OX40L with engineered Tregs., PMID:39485860
Making the effect visible - OX40 targeting nanobodies for in vivo imaging of activated T cells., PMID:39474429
IL-33-primed human mast cells drive IL-9 production by CD4+ effector T cells in an OX40L-dependent manner., PMID:39416773
NK Cell Degranulation Triggered by Rituximab Identifies Potential Markers of Subpopulations with Enhanced Cytotoxicity toward Malignant B Cells., PMID:39201666
Uncovering the Expression Pattern of the Costimulatory Receptors ICOS, 4-1BB, and OX-40 in Exhausted Peripheral and Tumor-Infiltrating Natural Killer Cells from Patients with Cervical Cancer., PMID:39201462
The Immunological Profile of Adipose Mesenchymal Stromal/Stem Cells after Cell Expansion and Inflammatory Priming., PMID:39062566
Association between OX40L polymorphism and type 2 diabetes mellitus in Iranians., PMID:38982447
The role of OX40 ligand/OX40 axis signalling in atopic dermatitis., PMID:38836560
The Role of OX40-OX40L Axis in the Pathogenesis of Atopic Dermatitis., PMID:38700255
Regulation of the Function of T Follicular Helper Cells and B Cells in Type 1 Diabetes Mellitus by the OX40/OX40L Axis., PMID:38625053
An OX-Tra'Ordinary Tale: The Role of OX40 and OX40L in Atopic Dermatitis., PMID:38607026
Single-cell profiling of response to neoadjuvant chemo-immunotherapy in surgically resectable esophageal squamous cell carcinoma., PMID:38566201
OX40/OX40 ligand and its role in precision immune oncology., PMID:38526805
Cross-talk between disulfidptosis and immune check point genes defines the tumor microenvironment for the prediction of prognosis and immunotherapies in glioblastoma., PMID:38365809
OX40 in the Pathogenesis of Atopic Dermatitis-A New Therapeutic Target., PMID:38236520
Comparative evaluation of antitumor effects of TNF superfamily costimulatory ligands delivered by mesenchymal stem cells., PMID:37995568
Construction and validation of a immune-related prognostic gene DHRS1 in hepatocellular carcinoma based on bioinformatic analysis., PMID:37861541
Ferroptosis-related lncRNAs guiding osteosarcoma prognosis and immune microenvironment., PMID:37858131
Anti-Tumor Immunogenicity of the Oncolytic Virus CF33-hNIS-antiPDL1 against Ex Vivo Peritoneal Cells from Gastric Cancer Patients., PMID:37762490
Sclerotic-Type Cutaneous Chronic Graft-Versus-Host Disease Exhibits Activation of T Helper 1 and OX40 Cytokines., PMID:37742913
Analysis of a new therapeutic target and construction of a prognostic model for breast cancer based on ferroptosis genes., PMID:37643511
Exploration of the association between the single-nucleotide polymorphism of co-stimulatory system and rheumatoid arthritis., PMID:37457686
Construction and validation of stemness-related lncRNA pair signature for predicting prognosis in colorectal cancer., PMID:37410143
The increased cfRNA of TNFSF4 in peripheral blood at late gestation and preterm labor: its implication as a noninvasive biomarker for premature delivery., PMID:37275889
Dysregulated early transcriptional signatures linked to mast cell and interferon responses are implicated in COVID-19 severity., PMID:37261339
Construction of an oxidative stress-related lncRNAs signature to predict prognosis and the immune response in gastric cancer., PMID:37258567
Inflammation and endothelial function-related gene polymorphisms are associated with carotid atherosclerosis-A study of community population in Southwest China., PMID:37137812
Toll-like receptor 7 agonist, GS-986, is an immune-stimulant inducing follicular helper T cells and expanding HBs antigen-specific B cells in vitro., PMID:37029645
Identification of an Immune-Related Gene Signature Associated with Prognosis and Tumor Microenvironment in Esophageal Cancer., PMID:36588538
Biological Activity of Mouse OX40L-Igg Purified With Two Novel Resins., PMID:39006201
Association between the side effect induced by COVID-19 vaccines and the immune regulatory gene polymorphism., PMID:36389676
Comprehensive characterization of costimulatory molecule gene for diagnosis, prognosis and recognition of immune microenvironment features in sepsis., PMID:36368641
Trans-ancestry, Bayesian meta-analysis discovers 20 novel risk loci for inflammatory bowel disease in an African American, East Asian and European cohort., PMID:36308435
Whole-genome sequencing unravels novel genetic determinants and regulatory pathways associated with triamcinolone acetonide-induced ocular hypertension., PMID:36222912
Investigation of the association between the genetic polymorphisms of the co-stimulatory system and systemic lupus erythematosus., PMID:36189300
Potential biomarkers for predicting the overall survival outcome of kidney renal papillary cell carcinoma: an analysis of ferroptosis-related LNCRNAs., PMID:36104680
Single-cell RNA sequencing depicts the local cell landscape in thyroid-associated ophthalmopathy., PMID:35896115
Interaction between BEND5 and RBPJ suppresses breast cancer growth and metastasis via inhibiting Notch signaling., PMID:35844785
TNFSF4 is a risk factor for rheumatoid arthritis but not for primary Sjögren's syndrome in the Mexican population., PMID:35835012
Single-Nucleotide Polymorphisms Within Non-HLA Regions Are Associated With Engraftment Effectiveness for Patients With Unrelated Cord Blood Transplantation., PMID:35769457
First report on genome wide association study in western Indian population reveals host genetic factors for COVID-19 severity and outcome., PMID:35680011
In Situ Reprogramming of Tumors for Activating the OX40/OX40 Ligand Checkpoint Pathway and Boosting Antitumor Immunity., PMID:35653749
Potential Key Markers for Predicting the Prognosis of Gastric Adenocarcinoma Based on the Expression of Ferroptosis-Related lncRNA., PMID:35528617
For research use only. Not for human or drug use.
