Catalog No.
EHC30501
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Met1-Asn250
Predicted molecular weight
52.63 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P08138
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Low affinity neurotrophin receptor p75NTR, TNFRSF16, CD271, Gp80-LNGFR, p75 ICD, Low-affinity nerve growth factor receptor, NGFR, NGF receptor, Tumor necrosis factor receptor superfamily member 16
Note
For research use only.
AbobotulinumtoxinA improves skin properties and sebum quality in the rhino mouse., PMID:37517594
Targeted Delivery of RGD-CD146+CD271+ Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Promotes Blood-Spinal Cord Barrier Repair after Spinal Cord Injury., PMID:37695238
Putative Cancer Stem Cell Markers are Frequently Expressed by Melanoma Cells in Vitro and in Situ but are also Present in Benign Differentiated Cells., PMID:37796710
Expression profiles of human somatic mesenchymal stem cells derived from fresh endometrium, ectopic-endometrium and umbilical cord., PMID:37934895
Feline SCCs of the Head and Neck Display Partial Epithelial-Mesenchymal Transition and Harbor Stem Cell-like Cancer Cells., PMID:38003753
CD271 promotes proliferation and migration in bladder cancer., PMID:38016691
Toward a human brain extracellular vesicle atlas: Characteristics of extracellular vesicles from different brain regions, including small RNA and protein profiles., PMID:38089920
Targeting AR-positive breast cancer cells via drug repurposing approach., PMID:38157661
ISX-9 Promotes KGF Secretion From MSCs to Alleviate ALI Through NGFR-ERK-TAU-β-Catenin Signaling Axis., PMID:38159248
Novel cellular systems unveil mucosal melanoma initiating cells and a role for PI3K/Akt/mTOR pathway in mucosal melanoma fitness., PMID:38191367
Heterogeneity-induced NGF-NGFR communication inefficiency promotes mitotic spindle disorganization in exhausted T cells through PREX1 suppression to impair the anti-tumor immunotherapy with PD-1 mAb in hepatocellular carcinoma., PMID:38204220
A positive feedback between PDIA3P1 and OCT4 promotes the cancer stem cell properties of esophageal squamous cell carcinoma., PMID:38254118
Mechanism of action of adapalene for treating EGFR-TKI-induced skin disorder., PMID:38379420
Retinoic acid receptor activation reprograms senescence response and enhances anti-tumor activity of natural killer cells., PMID:38428412
Intranasal delivery of small extracellular vesicles from specific subpopulation of mesenchymal stem cells mitigates traumatic spinal cord injury., PMID:38519036
[Different concentrations of adapalene induce differentiation and apoptosis of SH-SY5Y cells]., PMID:38557381
P75NTR+CD64+ neutrophils promote sepsis-induced acute lung injury., PMID:38599263
Role of basal cells in nasal polyp epithelium in the pathophysiology of eosinophilic chronic rhinosinusitis (eCRS)., PMID:38670810
CD271 mRNA/hnRNPA2B1 complex promotes proliferation and stemness in oral and head and neck squamous cell carcinoma., PMID:38710200
CSChighE-cadherinlow immunohistochemistry panel predicts poor prognosis in oral squamous cell carcinoma., PMID:38719848
Ethnicity-Based Variations in Focal Adhesion Kinase Signaling in Glioblastoma Gene Expression: A Study of the Puerto Rican Hispanic Population., PMID:38732165
p75 neurotrophin receptor modulation in mild to moderate Alzheimer disease: a randomized, placebo-controlled phase 2a trial., PMID:38760589
Cooperative interactions between neurotrophin receptors and CXCR4 regulate macrophage phenotype and susceptibility to activation by HIV., PMID:38822196
Cytokeratin 17 expression is commonly observed in keratinocytic skin tumours and controls tissue homeostasis impacting human papillomavirus protein expression., PMID:38878280
Extracellular matrices of stromal cell subtypes regulate phenotype and contribute to the stromal microenvironment in vivo., PMID:38886845
Identification of cellular and noncellular components of mature intact human peripheral nerve., PMID:38973168
PRRX1 silencing is required for metastatic outgrowth in melanoma and is an independent prognostic of reduced survival in patients., PMID:38978350
Induction of periodontal ligament-derived mesenchymal stromal cell-like cells from human induced pluripotent stem cells., PMID:39045575
Widespread Distribution of Luteinizing Hormone/Choriogonadotropin Receptor in Human Juvenile Angiofibroma: Implications for a Sex-Specific Nasal Tumor., PMID:39056799
SNORD88B-mediated WRN nucleolar trafficking drives self-renewal in liver cancer initiating cells and hepatocarcinogenesis., PMID:39112443
LM11A-31, a modulator of p75 neurotrophin receptor, suppresses HIV-1 replication and inflammatory response in macrophages., PMID:39119118
Brain plasticity and neuroinflammatory protein biomarkers with circulating MicroRNAs as predictors of acute brain injury outcome - A prospective cohort study., PMID:39126731
Adipocyte-secreted PRELP promotes adipocyte differentiation and adipose tissue fibrosis by binding with p75NTR to activate FAK/MAPK signaling., PMID:39244119
Efficient and cost-effective differentiation of induced neural crest cells from induced pluripotent stem cells using laminin 211., PMID:39290629
Alcohol use disorder disrupts BDNF maturation via the PAI-1 pathway which could be reversible with abstinence., PMID:39333668
The influence of fetal bovine serum concentration on stemness and neuronal differentiation markers in stem cells from human exfoliated deciduous teeth., PMID:39353229
Pulse Activation of Retinoic Acid Receptor Enhances Hematopoietic Stem Cell Homing by Controlling CXCR4 Membrane Presentation., PMID:39480614
Synthesis, characterisation, and anti-tumour activity of nano-immuno-conjugates for enhanced photodynamic therapy of oesophageal cancer stem cells., PMID:39550831
Resveratrol Can Differentiate Human Melanoma Stem-like Cells from Spheroids Treated With All-trans Retinoic Acid., PMID:39626925
CD9/SOX2-positive cells in the intermediate lobe of the rat pituitary gland exhibit mesenchymal stem cell characteristics., PMID:39808267
CD271 regulates osteogenic differentiation of ectomesenchymal stem cells via the RhoA/ROCK signaling pathway., PMID:39826451
CD271high cancer stem cells regulate macrophage polarization in head and neck squamous cell carcinoma., PMID:39854870
Extracellular vesicles from pancreatic cancer and its tumour microenvironment promote increased Schwann cell migration., PMID:39863771
Heterotypic interactions among members of the death domain superfamily with implications for p75NTR-mediated co-signaling., PMID:39924025
Oxidative Stress Suppresses Trk Signaling While Stimulating JNK-Mediated Endocytosis and Cleavage of p75NTR: A Targetable Pathway for Neuroprotection in a Parkinson's Disease Model., PMID:39936238
Dual role of interferon-gamma in the response of melanoma patients to immunotherapy with immune checkpoint inhibitors., PMID:40108693
CD271 Serves as a Marker for Tumor-Initiating Cells in Laryngocarcinoma., PMID:40116102
Injectable Functional Microspheres Capable of BMSC Recruitment and Osteogenic Induction for In Situ Bone Regeneration., PMID:40131171
Dysregulation of proBDNF/p75NTR and BDNF/TrkB Signaling in Acute Ischemic Stroke: Different Sides of the Same Coins., PMID:40209946
Transcriptional evidence of reduced BDNF trophic capacity in the post-mortem human midbrain of schizophrenia cases with high inflammation., PMID:40335479
For research use only. Not for human or drug use.
