Catalog No.
DHD17409
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Human
Isotype
IgG
Clonality
Monoclonal
Applications
Research Grade Biosimilar
Target
Epithelial glycoprotein 314, hEGP314, Major gastrointestinal tumor-associated protein GA733-2, EGP314, TACSTD1, Adenocarcinoma-associated antigen, TROP1, EPCAM, Epithelial glycoprotein, KS 1/4 antigen, Tumor-associated calcium signal transducer 1, M4S1, CD326, Ep-CAM, EGP, Epithelial cell adhesion molecule, M1S2, KSA, Cell surface glycoprotein Trop-1, GA733-2, Epithelial cell surface antigen, MIC18
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P16422
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
AFM20
Clone ID
AFM20
Note
For research use only. Not suitable for clinical or therapeutic use.
Generating tumor-selective conditionally active biologic anti-CTLA4 antibodies via protein-associated chemical switches., PMID:33627407
Intracellular KRAS-specific antibody enhances the anti-tumor efficacy of gemcitabine in pancreatic cancer by inducing endosomal escape., PMID:33744388
Heterogeneous Manifestations of Epithelial-Mesenchymal Plasticity of Circulating Tumor Cells in Breast Cancer Patients., PMID:33801519
Immunoengineered magnetic-quantum dot nanobead system for the isolation and detection of circulating tumor cells., PMID:33892737
Intraperitoneal EpCAM-Targeted Immunotoxin: A First Step Towards Engineering the Immune Environment in Colorectal Peritoneal Metastases?, PMID:33993377
A Modified Method to Isolate Circulating Tumor Cells and Identify by a Panel of Gene Mutations in Lung Cancer., PMID:34032165
Development of a recombinant anti-VEGFR2-EPCAM bispecific antibody to improve antiangiogenic efficiency., PMID:34090863
Heterogeneity and prognosis of programmed cell death-ligand 1 expression in the circulating tumor cells of non-small cell lung cancer., PMID:34097427
An integrated magneto-electrochemical device for the rapid profiling of tumour extracellular vesicles from blood plasma., PMID:34183802
The myeloid cell biomarker EMR1 is ectopically expressed in colon cancer., PMID:34486997
The combination therapy with EpCAM/CD3 BsAb and MUC-1/CD3 BsAb elicited antitumor immunity by T-cell adoptive immunotherapy in lung cancer., PMID:34522164
Recombinant thrombomodulin attenuates hyper-inflammation and glycocalyx damage in a murine model of Streptococcus pneumoniae-induced sepsis., PMID:34662822
Removal of EpCAM-positive tumor cells from blood collected during major oncological surgery using the Catuvab device- a pilot study., PMID:34715784
MACSima imaging cyclic staining (MICS) technology reveals combinatorial target pairs for CAR T cell treatment of solid tumors., PMID:35115587
Epithelial cell adhesion molecule (EpCAM) binding short peptides derived from antibody MOC-31; De-novo design, synthesis and their in-vitro evaluation., PMID:35182969
Human-Immune-System (HIS) humanized mouse model (DRAGA: HLA-A2.HLA-DR4.Rag1KO.IL-2RγcKO.NOD) for COVID-19., PMID:35348437
EpCAM-positive disseminated cancer cells in bone marrow impact on survival of early-stage NSCLC patients., PMID:35421717
CD39 and CD326 Are Bona Fide Markers of Murine and Human Plasma Cells and Identify a Bone Marrow Specific Plasma Cell Subpopulation in Lupus., PMID:35464469
Near-infrared photoimmunotherapy induced tumor cell death enhances tumor dendritic cell migration., PMID:35624180
EpCAM- and EGFR-Specific Antibody Drug Conjugates for Triple-Negative Breast Cancer Treatment., PMID:35682800
Routine flow cytometry approach for the evaluation of solid tumor neoplasms and immune cells in minimally invasive samples., PMID:35703585
Cryobanking of Human Distal Lung Epithelial Cells for Preservation of Their Phenotypic and Functional Characteristics., PMID:36036918
Oncolytic vaccinia virus expressing a bispecific T-cell engager enhances immune responses in EpCAM positive solid tumors., PMID:36451817
Antibody screening data of human midgestation liver cells with a focus on hematopoietic, liver sinusoidal endothelial, and hepatoblast cell-populations., PMID:36474299
Diagnostic Value of Epithelial Cell Adhesion Molecule Flow Cytometry for Diagnosis of Metastatic Carcinoma in Serous Effusions., PMID:36626892
Feasibility of Co-Targeting HER3 and EpCAM Using Seribantumab and DARPin-Toxin Fusion in a Pancreatic Cancer Xenograft Model., PMID:36769161
Immunocapturing rare cells from blood: A simple and robust microsystem approach., PMID:36821992
Comparative analysis of EpCAM high-expressing and low-expressing circulating tumour cells with regard to their clonal relationship and clinical value., PMID:36823365
ROCKETS - a novel one-for-all toolbox for light sheet microscopy in drug discovery., PMID:36845124
CD203c is expressed by human fetal hepatoblasts and distinguishes subsets of hepatoblastoma., PMID:36845728
Fine-tuning spatial-temporal dynamics and surface receptor expression support plasma cell-intrinsic longevity., PMID:36891288
Magnetic Separation of Cell-Secreted Vesicles with Tailored Magnetic Particles and Downstream Applications., PMID:37140802
Skin Whole-Mount Immunofluorescent Staining Protocol, 3D Visualization, and Spatial Image Analysis., PMID:37338194
A CD326 monoclonal antibody modified core cross-linked curcumin-polyphosphoester prodrug for targeted delivery and cancer treatment., PMID:37782068
Detection of effusion tumor cells under different storage and processing conditions., PMID:38373107
BerEP4-Negative Basal Cell Carcinoma: An Immunophenotype Not to Forget., PMID:38457681
Utilizing Magnetic Levitation to Detect Lung Cancer-Associated Exosomes., PMID:38520356
Fine-tuning spatial-temporal dynamics and surface receptor expression support plasma cell-intrinsic longevity., PMID:38896451
Fluorescent identification of immunomagnetically captured CTCs using triplex-aptamer-targeted dendritic SiO2@Fe3O4 nanocomposite., PMID:38922365
Intracellular domain of epithelial cell adhesion molecule induces Wnt receptor transcription to promote colorectal cancer progression., PMID:39010070
Chimeric antigen receptor-T cells targeting epithelial cell adhesion molecule antigens are effective in the treatment of colorectal cancer., PMID:39107717
Durable response to pembrolizumab in hepatic metastasis from colonic carcinoma with Lynch syndrome: a case report., PMID:39247185
ImmunoPET imaging of EpCAM in solid tumours with nanobody tracers: a preclinical study., PMID:39249490
Combining rVAR2 and Anti-EpCAM to Increase the Capture Efficiency of Non-Small-Cell Lung Cancer Cell Lines in the Flow Enrichment Target Capture Halbach (FETCH) Magnetic Separation System., PMID:39337304
Enhanced capture system for mesenchymal‑type circulating tumor cells using a polymeric microfluidic device 'CTC‑Chip' incorporating cell‑surface vimentin., PMID:39364763
Clinicopathologic Characteristics of Trop Family Proteins (Trop-2 and EpCAM) in Gastric Carcinoma., PMID:39375055
High-Affinity Fully Human Anti-EpCAM Antibody with Biased IL-2 Exhibits Potent Antitumor Activity., PMID:39595576
Optimizing combination targeted immunotoxin therapy: Insights from HER2 and EpCAM expression profiles., PMID:39752974
The interplay of cancer-associated fibroblasts and apoptotic cancer cells suppresses lung cancer cell growth through WISP-1-integrin ανβ3-STAT1 signaling pathway., PMID:39966869
Dual-antibody functionalized transistor biosensor for specific diagnosis of liver cancer., PMID:40203597
For research use only. Not for human or drug use.
