Research Grade Anti-Human MET/c-Met/HGFR (MvDN30)

Catalog No.

DHC34217

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Human

Isotype

IgG

Clonality

Monoclonal

Target

Tyrosine-protein kinase Met, Hepatocyte growth factor receptor, Proto-oncogene c-Met, Scatter factor receptor, HGF receptor, SF receptor, HGF/SF receptor, MET

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P08581

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

MvDN30

Clone ID

MvDN30

Met inhibition revokes IFNγ-induction of PD-1 ligands in MET-amplified tumours., PMID:30723303

Targeting the MET oncogene by concomitant inhibition of receptor and ligand via an antibody-"decoy" strategy., PMID:29693242

Dual Constant Domain-Fab: A novel strategy to improve half-life and potency of a Met therapeutic antibody., PMID:27103110

Inhibition of ligand-independent constitutive activation of the Met oncogenic receptor by the engineered chemically-modified antibody DN30., PMID:26119717

Increase of MET gene copy number confers resistance to a monovalent MET antibody and establishes drug dependence., PMID:25011627

Targeted therapy by gene transfer of a monovalent antibody fragment against the Met oncogenic receptor., PMID:24013625

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Research Grade Anti-Human MET/c-Met/HGFR (MvDN30).pdf