Catalog No.
DHF19808
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Human
Isotype
IgG
Clonality
Monoclonal
Target
Claudin-18, CLDN18
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P56856
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
CT041
Clone ID
CT041
Claudin-18 isoform 2-specific CAR T-cell therapy (satri-cel) versus treatment of physician's choice for previously treated advanced gastric or gastro-oesophageal junction cancer (CT041-ST-01): a randomised, open-label, phase 2 trial., PMID:40460847
Exploring the therapeutic efficacy difference in claudin18.2-targeted cell therapy revealed by single-cell sequencing., PMID:39925434
Erratum: Safety and Efficacy of CT041 in Patients With Refractory Metastatic Pancreatic Cancer: A Pooled Analysis of Two Early-Phase Trials., PMID:39083710
Claudin18.2-specific CAR T cells in gastrointestinal cancers: phase 1 trial final results., PMID:38830992
Safety and Efficacy of CT041 in Patients With Refractory Metastatic Pancreatic Cancer: A Pooled Analysis of Two Early-Phase Trials., PMID:38788174
Clinicopathological significance and immunotherapeutic outcome of claudin 18.2 expression in advanced gastric cancer: A retrospective study., PMID:38455365
Metastatic gastric cancer target lesion complete response with Claudin18.2-CAR T cells., PMID:38316518
CT041 CAR T cell therapy for Claudin18.2-positive metastatic pancreatic cancer., PMID:37689733
Claudin18.2-specific CAR T cells in gastrointestinal cancers: phase 1 trial interim results., PMID:35534566
For research use only. Not for human or drug use.
