Catalog No.
PHA73501
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human PSCA (Leu12-Ser86).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:200, WB: 1:1000-1:4000
Target
Prostate stem cell antigen,PSCA
Concentration
1.6 mg/ml
Purification
Purified by antigen affinity column.
Accession
O43653
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
A facile yeast-display approach for antibody mask discovery., PMID:40381213
Impact of tumor localization on antitumor immunity with conditionally activated CTLA-4 blockade., PMID:40180419
Targeting the tumour cell surface in advanced prostate cancer., PMID:40169837
Developmental Therapeutics in Metastatic Prostate Cancer: New Targets and New Strategies., PMID:39272956
Immunoliposome-based targeted delivery of the CRISPR/Cas9gRNA-IL30 complex inhibits prostate cancer and prolongs survival., PMID:39232121
Discovery of a novel highly specific, fully human PSCA antibody and its application as an antibody-drug conjugate in prostate cancer., PMID:39113562
T-Cell redirecting bispecific antibodies: a review of a novel class of immuno-oncology for advanced prostate cancer., PMID:38801069
64Cu tumor labeling with hexadentate picolinic acid-based bispidine immunoconjugates., PMID:38506263
Tandem CAR-T cells targeting MUC1 and PSCA combined with anti-PD-1 antibody exhibit potent preclinical activity against non-small cell lung cancer., PMID:37660477
Fabrication of Antibody Conjugated Super Magnetic Oxide Nanoparticles for Early Detection of Prostate Cancer., PMID:37378940
Bispecific PSMA antibodies and CAR-T in metastatic castration-resistant prostate cancer., PMID:37359737
Preclinical Characterization of the 177Lu-Labeled Prostate Stem Cell Antigen (PSCA)-Specific Monoclonal Antibody 7F5., PMID:37298374
Palbociclib impairs the proliferative capacity of activated T cells while retaining their cytotoxic efficacy., PMID:36817127
Development and Functional Characterization of a Versatile Radio-/Immunotheranostic Tool for Prostate Cancer Management., PMID:35454902
Targeted Transposition of Minicircle DNA Using Single-Chain Antibody Conjugated Cyclodextrin-Modified Poly (Propylene Imine) Nanocarriers., PMID:35454835
Novel Redirected T-Cell Immunotherapies for Advanced Prostate Cancer., PMID:34675084
Post-transplant Cyclophosphamide Versus Thymoglobulin in HLA-Mismatched Unrelated Donor Transplant for Acute Myelogenous Leukemia and Myelodysplastic Syndrome., PMID:34174469
Targeted RNAi of BIRC5/Survivin Using Antibody-Conjugated Poly(Propylene Imine)-Based Polyplexes Inhibits Growth of PSCA-Positive Tumors., PMID:34066833
Immunotherapy of prostate cancer using novel synthetic DNA vaccines targeting multiple tumor antigens., PMID:33884106
The Anti-Proliferative Effect of a Newly-Produced Anti-PSCA-Peptide Antibody by Multiple Bioinformatics Tools, on Prostate Cancer Cells., PMID:33176663
Serum total prostate-specific antigen (tPSA): correlation with diagnosis and grading of prostate cancer in core needle biopsy., PMID:32815673
Evaluation of [131I]I- and [177Lu]Lu-DTPA-A11 Minibody for Radioimmunotherapy in a Preclinical Model of PSCA-Expressing Prostate Cancer., PMID:32661830
In Pursuit of Stability Enhancement of a Prostate Cancer Targeting Antibody Derived from a Transgenic Animal Platform., PMID:32546687
Artificial feeder cells expressing ligands for killer cell immunoglobulin-like receptors and CD94/NKG2A for expansion of functional primary natural killer cells with tolerance to self., PMID:32451262
Bovine papillomavirus prostate cancer antigen virus-like particle vaccines are efficacious in advanced cancers in the TRAMP mouse spontaneous prostate cancer model., PMID:32016503
Tri-functional platform for construction of modular antibody fragments for in vivo 18F-PET or NIRF molecular imaging., PMID:34123276
Impact of PSCA Polymorphisms on the Risk of Duodenal Ulcer., PMID:31839644
In-vitro prostate cancer biomarker detection by directed conjugation of anti-PSCA antibody to super paramagnetic iron oxide nanoparticless., PMID:31380306
[89Zr]A2cDb Immuno-PET of Prostate Cancer in a Human Prostate Stem Cell Antigen Knock-in (hPSCA KI) Syngeneic Model., PMID:31209779
A Dual-Modality Linker Enables Site-Specific Conjugation of Antibody Fragments for 18F-Immuno-PET and Fluorescence Imaging., PMID:30877181
Targeted delivery of TLR3 agonist to tumor cells with single chain antibody fragment-conjugated nanoparticles induces type I-interferon response and apoptosis., PMID:30824859
Dual-Modality ImmunoPET/Fluorescence Imaging of Prostate Cancer with an Anti-PSCA Cys-Minibody., PMID:30613270
Quantum dot-based fluorescent probes for targeted imaging of the EJ human bladder urothelial cancer cell line., PMID:30546399
Near-Infrared Dye-Labeled Anti-Prostate Stem Cell Antigen Minibody Enables Real-Time Fluorescence Imaging and Targeted Surgery in Translational Mouse Models., PMID:30301826
Improved Conjugation, 64-Cu Radiolabeling, in Vivo Stability, and Imaging Using Nonprotected Bifunctional Macrocyclic Ligands: Bis(Phosphinate) Cyclam (BPC) Chelators., PMID:30180567
Dual-Modality Immuno-PET and Near-Infrared Fluorescence Imaging of Pancreatic Cancer Using an Anti-Prostate Stem Cell Antigen Cys-Diabody., PMID:29602820
Evaluation of a Pretargeting Strategy for Molecular Imaging of the Prostate Stem Cell Antigen with a Single Chain Antibody., PMID:29491468
Multiplex Gene Expression Profiling of In Vivo Isolated Circulating Tumor Cells in High-Risk Prostate Cancer Patients., PMID:29122836
Formulation of the bivalent prostate cancer vaccine with surgifoam elicits antigen-specific effector T cells in PSA-transgenic mice., PMID:28939158
Exploratory investigation of PSCA-protein expression in primary breast cancer patients reveals a link to HER2/neu overexpression., PMID:28903367
Atopy and prostate cancer: Is there a link between circulating levels of IgE and PSA in humans?, PMID:28795218
Novel PSCA targeting scFv-fusion proteins for diagnosis and immunotherapy of prostate cancer., PMID:28667390
Interaction of the Mineralocorticoid Receptor With RACK1 and Its Role in Aldosterone Signaling., PMID:28472300
Construction of a fusion plasmid containing the PSCA gene and cytotoxic T-lymphocyte associated antigen-4 (CTLA-4) and its anti-tumor effect in an animal model of prostate cancer., PMID:27783810
Engineering A11 Minibody-Conjugated, Polypeptide-Based Gold Nanoshells for Prostate Stem Cell Antigen (PSCA)-Targeted Photothermal Therapy., PMID:27659802
Fluorescent Image-Guided Surgery with an Anti-Prostate Stem Cell Antigen (PSCA) Diabody Enables Targeted Resection of Mouse Prostate Cancer Xenografts in Real Time., PMID:26490315
Nanoparticle mediated chemotherapy of hormone refractory prostate cancer with a novel combi-molecule., PMID:26396674
A genome-wide association study for clinical mastitis in first parity US Holstein cows using single-step approach and genomic matrix re-weighting procedure., PMID:25658712
Applications of immunoPET: using 124I-anti-PSCA A11 minibody for imaging disease progression and response to therapy in mouse xenograft models of prostate cancer., PMID:25326233
Redirection of CD4+ and CD8+ T lymphocytes via a novel antibody-based modular targeting system triggers efficient killing of PSCA+ prostate tumor cells., PMID:25053504
For research use only. Not for human or drug use.
