Research Grade Anti-Human CD269/TNFRSF17/BCMA (HDP-101)

Catalog No.

DHF92416

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Human

Isotype

IgG

Clonality

Monoclonal

Applications

Research Grade Biosimilar

Target

Tumor necrosis factor receptor superfamily member 17, TNFRSF17, CD269, B-cell maturation protein, BCMA, BCM

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q02223

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

HDP-101, HDP 101, HDP101

Clone ID

HDP-101

Note

For research use only. Not suitable for clinical or therapeutic use.

Amanitins and their development as a payload for antibody-drug conjugates., PMID:30553524

CRISPR-based screens uncover determinants of immunotherapy response in multiple myeloma., PMID:32589729

HDP-101, an Anti-BCMA Antibody-Drug Conjugate, Safely Delivers Amanitin to Induce Cell Death in Proliferating and Resting Multiple Myeloma Cells., PMID:33298585

Novel Anti-B-cell Maturation Antigen Alpha-Amanitin Antibody-drug Conjugate HDP-101 Shows Superior Activity to Belantamab Mafodotin and Enhanced Efficacy in Deletion 17p Myeloma Models., PMID:38260385

Document Download

Research Grade Anti-Human CD269/TNFRSF17/BCMA (HDP-101).pdf