Please ensure Javascript is enabled for purposes of website accessibility
Home / Products / Research Biosimilar

Research Grade Anti-Human CD166/ALCAM (AT002)

Catalog #:   DHG64002 Specific References (50) DATASHEET
Host species: Human
Isotype: IgG
Applications: Research Grade Biosimilar
Expression system: Mammalian Cells
Overview

Catalog No.

DHG64002

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Human

Isotype

IgG

Clonality

Monoclonal

Target

Activated leukocyte cell adhesion molecule, MEMD, CD166 antigen, ALCAM, CD166

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q13740

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

AT002

Clone ID

AT002

Data Image
References

Ex vivo expansion of human disc chondrocytes from surgically removed disc tissue: Post-operative tissue stability., PMID:40501087

The cytotoxic effect of quercetin-induced apoptosis on lung metastatic cells from giant cell tumor of bone., PMID:40418557

Itolizumab regulates activating and inhibitory signals on effector cells, improving their cytotoxicity against CD318+ tumor cell lines., PMID:40391211

Activation of cytotoxic lymphocytes through CD6 enhances killing of cancer cells., PMID:38280067

CD6 and Its Interacting Partners: Newcomers to the Block of Cancer Immunotherapies., PMID:38139340

Activation of Cytotoxic Lymphocytes Through CD6 Enhances Killing of Cancer Cells., PMID:37886483

Targeting Stem Cells and Dysplastic Features With Dual MEK/ERK and STAT3 Suppression in Gastric Carcinogenesis., PMID:37802423

Comprehensive cell surface protein profiling of human mesenchymal stromal cells from peritoneal dialysis effluent and comparison with those from human bone marrow and adipose tissue., PMID:37603218

The influence of antibody CD166 on the treatment of tumor and the immunological mechanism in mice bearing oral squamous cell carcinoma., PMID:37180656

Mesenchymal stromal cell-associated migrasomes: a new source of chemoattractant for cells of hematopoietic origin., PMID:36788616

Keratinocyte-induced costimulation of human T cells through CD6 - but not CD2 - activates mTOR and prevents oxidative stress., PMID:36353616

Proteomic Analysis of HCC-1954 and MCF-7 Cell Lines Highlights Crosstalk between αv and β1 Integrins, E-Cadherin and HER-2., PMID:36077593

Preventive cancer stem cell-based vaccination modulates tumor development in syngeneic colon adenocarcinoma murine model., PMID:36040667

Proteomics Study of Mesenchymal Stem Cell-Like Cells Obtained from Tumor Microenvironment of Patients with Malignant and Benign Salivary Gland Tumors., PMID:35674025

Gene Variation at Immunomodulatory and Cell Adhesion Molecules Loci Impacts Primary Sjögren's Syndrome., PMID:35372412

Praluzatamab Ravtansine, a CD166-Targeting Antibody-Drug Conjugate, in Patients with Advanced Solid Tumors: An Open-Label Phase I/II Trial., PMID:35165101

Adipose mesenchymal stem cells and gingival mesenchymal stem cells have a comparable effect in endothelium repair., PMID:34676008

Calcium channel α2δ1 subunit is a functional marker and therapeutic target for tumor-initiating cells in non-small cell lung cancer., PMID:33707423

Simultaneous Fluorescent Identification of Odontoblasts and Ameloblasts., PMID:33289448

A novel molecular magnetic resonance imaging agent targeting activated leukocyte cell adhesion molecule as demonstrated in mouse brain metastasis models., PMID:33153376

SOSTDC1 promotes invasion and liver metastasis in colorectal cancer via interaction with ALCAM/CD166., PMID:32801337

Stem Cell Marker Expression in Early Stage Colorectal Cancer is Associated with Recurrent Intestinal Neoplasia., PMID:32647988

The tumor targeting performance of anti-CD166 Probody drug conjugate CX-2009 and its parental derivatives as monitored by 89Zr-immuno-PET in xenograft bearing mice., PMID:32483421

Plasmacytoma in patients with multiple myeloma: morphology and immunohistochemistry., PMID:32321465

Attenuation of Murine Collagen-Induced Arthritis by Targeting CD6., PMID:32307907

In silico Analysis, Molecular Docking, Molecular Dynamic, Cloning, Expression and Purification of Chimeric Protein in Colorectal Cancer Treatment., PMID:32158188

Effect of Rho-associated kinase inhibitor on human corneal endothelial cell apoptosis., PMID:32079844

Radiation-Stimulated Translocation of CD166 and CRYAB to the Endothelial Surface Provides Potential Vascular Targets on Irradiated Brain Arteriovenous Malformations., PMID:31757032

Activated leukocyte cell adhesion molecule regulates B lymphocyte migration across central nervous system barriers., PMID:31723036

Enhanced Immunomodulation in Inflammatory Environments Favors Human Cardiac Mesenchymal Stromal-Like Cells for Allogeneic Cell Therapies., PMID:31396228

Axonal Growth of Midbrain Dopamine Neurons is Modulated by the Cell Adhesion Molecule ALCAM Through Trans-Heterophilic Interactions with L1cam, Chl1, and Semaphorins., PMID:31300520

Quantitative Systems Pharmacology Model of a Masked, Tumor-Activated Antibody., PMID:31250966

Domain-specific CD6 monoclonal antibodies identify CD6 isoforms generated by alternative-splicing., PMID:31162836

Back signaling of HLA class I molecules and T/NK cell receptor ligands in epithelial cells reflects the rejection-specific microenvironment in renal allograft biopsies., PMID:31062482

ALCAM Mediates DC Migration Through Afferent Lymphatics and Promotes Allospecific Immune Reactions., PMID:31031759

Anti-CD166/4-1BB chimeric antigen receptor T cell therapy for the treatment of osteosarcoma., PMID:30995926

Isolation and Identification of Murine Bone Marrow-Derived Macrophages and Osteomacs from Neonatal and Adult Mice., PMID:30539348

A sequence conserved between CD5 and CD6 binds an FERM domain and exerts a restraint on T-cell activation., PMID:30460991

Mapping of equine mesenchymal stromal cell surface proteomes for identification of specific markers using proteomics and gene expression analysis: an in vitro cross-sectional study., PMID:30359315

Prophylactic exposure of human corneal endothelial cells to Rho-associated kinase inhibitor reduced apoptosis rate after phacoemulsification: Ex vivo study., PMID:30172567

Stemness and Regenerative Potential of Corneal Stromal Stem Cells and Their Secretome After Long-Term Storage: Implications for Ocular Regeneration., PMID:30046814

CD6 monoclonal antibodies differ in epitope, kinetics and mechanism of action., PMID:29772075

Clinical and experimental evidence for targeting CD6 in immune-based disorders., PMID:29526637

Isolation and characterization of buffalo (bubalus bubalis) amniotic mesenchymal stem cells derived from amnion from the first trimester pregnancy., PMID:29515060

Activated leucocyte cell adhesion molecule (ALCAM/CD166) regulates T cell responses in a murine model of food allergy., PMID:29363753

ILT3.Fc-CD166 Interaction Induces Inactivation of p70 S6 Kinase and Inhibits Tumor Cell Growth., PMID:29263213

A novel bispecific c-MET/CTLA-4 antibody targetting lung cancer stem cell-like cells with therapeutic potential in human non-small-cell lung cancer., PMID:29187584

Tbx18-positive cells differentiated from murine ES cells serve as proepicardial progenitors to give rise to vascular smooth muscle cells and fibroblasts., PMID:28794400

Different RNA and protein expression of surface markers in rabbit amniotic fluid-derived mesenchymal stem cells., PMID:28653478

Intestinal Epithelial Stem Cells: Distinct Behavior After Surgical Injury and Teduglutide Administration., PMID:28362133

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1486

Contact Information

Order: order@antibodysystem.com

Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

Need help with your order?

Find out more about placing an order here

Research Grade Anti-Human CD166/ALCAM (AT002) [DHG64002]
Terms of sale Website terms of use Cookie policy Privacy
Copyright © 2025 AntibodySystem SAS. All Rights Reserved.            All Products are for Research Use Only