Catalog No.
DHD14209
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Mouse
Isotype
IgG1, kappa
Clonality
Monoclonal
Target
PEMT, CA 15-3, H23AG, Peanut-reactive urinary mucin, PEM, EMA, Cancer antigen 15-3, MUC-1, Episialin, MUC1-CT, MUC1-beta, Tumor-associated mucin, CD227, Polymorphic epithelial mucin, KL-6, MUC1-alpha, MUC1, PUM, Krebs von den Lungen-6, MUC1-NT, Tumor-associated epithelial membrane antigen, Mucin-1, Breast carcinoma-associated antigen DF3, Carcinoma-associated mucin
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P15941
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
Pemtumomab
Clone ID
Pemtumomab
Staining of MUC1 in ovarian cancer tissues with PankoMab-GEX detecting the tumour-associated epitope, TA-MUC1, as compared to antibodies HMFG-1 and 115D8., PMID:23275306
MUC1 immunotherapy., PMID:20635898
Xanthogranulomatous reaction to a ruptured galactocele., PMID:20202042
Human anti-mouse IgM and IgG responses in ovarian cancer patients after radioimmunotherapy with 90Y-muHMFG1., PMID:19035301
Toll-like receptor agonists and invariant natural killer T-cells enhance antibody-dependent cell-mediated cytotoxicity (ADCC)., PMID:18684557
Induction of IgG antibodies to MUC1 and survival in patients with epithelial ovarian cancer., PMID:18661524
MUC-1 mucin in normal human salivary glands detected by HMFG-1 and HMFG-2 monoclonal antibodies., PMID:18321359
The MUC1 HMFG1 glycoform is a precursor to the 214D4 glycoform in the human uterine epithelial cell line, HES., PMID:17989354
Development of ELISAs for quantification of HMFG1-specific human anti-mouse IgG and IgM antibodies., PMID:17922458
Extraperitoneal leakage as a possible explanation for failure of one-time intraperitoneal treatment in ovarian cancer., PMID:17803445
High level of MUC1 in serum of ovarian and breast cancer patients inhibits huHMFG-1 dependent cell-mediated cytotoxicity (ADCC)., PMID:17692456
Decreased intraperitoneal disease recurrence in epithelial ovarian cancer patients receiving intraperitoneal consolidation treatment with yttrium-90-labeled murine HMFG1 without improvement in overall survival., PMID:17354223
Monoclonal and bispecific antibodies as novel therapeutics., PMID:16648969
Phase III trial of intraperitoneal therapy with yttrium-90-labeled HMFG1 murine monoclonal antibody in patients with epithelial ovarian cancer after a surgically defined complete remission., PMID:16446329
Consolidation for ovarian cancer in remission., PMID:16446325
Concurrent radiotherapy and tumor targeting with 111In-HMFG1-F(ab')2 in patients with MUC1-positive non-small cell lung cancer., PMID:16334158
Characterisation and internalisation of recombinant humanised HMFG-1 antibodies against MUC1., PMID:16265351
[Immunotherapy--perspectives in therapy of ovarian carcinomas]., PMID:15587893
Gastric metaplasia and small bowel ulcerogenesis in a case of ulcerative jejunitis not related to celiac disease., PMID:15494871
Reversal of glandular polarity in the lymphovascular compartment of breast cancer., PMID:15452174
Impact of antibody framework residue VH-71 on the stability of a humanised anti-MUC1 scFv and derived immunoenzyme., PMID:15150594
A phase I trial of idiotypic vaccination with HMFG1 in ovarian cancer., PMID:15127236
Intraperitoneal radioimmunotherapy in an ovarian carcinoma mouse model: Effect of the radionuclide., PMID:14675343
Technology evaluation: R-1549, Antisoma/Roche., PMID:14601527
Biologic and immunologic therapies for ovarian cancer., PMID:12743131
SMART? Time will tell., PMID:12442760
Application of extracorporeal immunoadsorption to reduce circulating blood radioactivity after intraperitoneal administration of indium-111-HMFG1-biotin., PMID:11877758
For research use only. Not for human or drug use.
