Catalog No.
DHJ72801
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Humanized
Isotype
IgG1-kappa
Clonality
Monoclonal
Target
IL1R-rp2, IL1RL2, IL1RRP2, IL-1Rrp2, IL-36 receptor, Interleukin-1 receptor-related protein 2, Interleukin-1 receptor-like 2, IL-36R
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9HB29
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
BI 655130, BI655130, MAB92,CAS: 2097104-58-8
Clone ID
Spesolimab
Note
For research use only. Not suitable for clinical or therapeutic use.
Association between lactate dehydrogenase to albumin ratio and ICU mortality in patients with acute kidney injury: a retrospective cohort study., PMID:40530353
Predicting transient performance of a heavy-duty gaseous-fuelled engine using combined phenomenological and machine learning models., PMID:40530355
Sex Hormone Levels and Pain Thresholds in the Luteal Phase of Healthy Women., PMID:40530358
Isolated Feet Edema in Turner Syndrome by Prenatal Ultrasonography - Case Report and Literature Review., PMID:40530359
Retrospective Analysis of Gut Microbiota and Metabolomic Profiles in Pregnant Women: Association with Cesarean Section Risk., PMID:40530360
Recent advances on the mechanism of acupuncture in the treatment of subjective tinnitus., PMID:40530363
Accounting for Withdrawal of Life-Sustaining Treatment in the Analysis of Traumatic Brain Injury Studies., PMID:40530366
Pharmacist-Driven Deprescribing to Reduce Anticholinergic Burden in Veterans With Dementia., PMID:40530371
Antenatal screening for TB disease: a systematic review and meta-analysis., PMID:40530378
Progress and challenges to TB elimination in New South Wales, Australia., PMID:40530385
Sodium houttuyfonate inhibits the cariogenic virulence of Streptococcus mutans through the downregulation of VicRK two components pathway., PMID:40530386
Targeting ApoE-KCC2 Signaling Rescues GABAergic Synaptic Dysfunction and Depression-like Behaviors in Mice., PMID:40530388
Black Women as Superwomen? The Mental Health Effects of Superwoman Schema, Socioeconomic Status, and Financial Strain., PMID:40530389
Sudden Cardiac Arrest With Ventricular Fibrillation in a Patient With Epilepsy and a Vagus Nerve Stimulator., PMID:40530393
Exploring the potential of honokiol as a treatment for cardiovascular disease (Review)., PMID:40530396
Effect of Locoregional Vs General Anesthesia on Incidence of Delayed Neurocognitive Recovery in Patients Undergoing Hip Fracture Surgery: A Randomized Controlled Trial., PMID:40530400
Fu's Subcutaneous Needling Combined with Kinematic Acupuncture versus Electroacupuncture in the Treatment of Cervical Spondylotic Radiculopathy: A Randomized Controlled Trial [Letter]., PMID:40530401
Exploring Psychedelics for Unmet Needs in Women's Reproductive Health., PMID:40530407
Real-time magnetic resonance visualization of tumor acidosis as a precognition indicator of therapeutic efficacy., PMID:40530412
A dual-targeting strategy to inhibit colorectal cancer liver metastasis via tumor cell ferroptosis and cancer-associated fibroblast reprogramming., PMID:40530415
Exploring LLM-powered multi-session human-robot interactions with university students., PMID:40530417
Adjuvant conditioning shapes the adaptive immune response promoting immunotolerance via NLRP3/interleukin-1., PMID:40530419
Neodymium-modified Mg-Zn-Zr magnesium alloy as a biodegradable osteogenic implant., PMID:40530420
Treatment outcomes of successful M1 versus M2 thrombectomy for low-ASPECTS stroke patients., PMID:40530425
Alleviation of myocardial infarction by hydrogen sulfide-releasing nanoparticles: mechanisms and therapeutic effects., PMID:40530426
Efficacy of Mesenchymal Stem Cells in the Treatment of Diabetic Foot Ulcers: A Meta-Analysis of Randomized Controlled Trials., PMID:40530428
Relationships Between Nutrition Risk and Frailty in Candidates for Lung Transplant., PMID:40530437
Desire for Sterilization Reversal in Delaware, US: The Roles of LARC Use, Personal Abortion Acceptability, and Economic Disadvantage., PMID:40530438
Immunomodulatory green nanomedicine production, tumor cellular targeting, in vivo biodistributions and preclinical therapeutic efficacy investigations of resveratrol-functionalized gold and theranostic 198gold nanoparticles., PMID:40530440
Phenotype-specific dynamics of serum albumin and their impact on sepsis mortality., PMID:40530442
Field evaluation of an agricultural weed detector using YOLO image recognition: background conditions affect detection performance., PMID:40530444
Relevance of GDF15 as a biomarker for clinical outcomes after bariatric surgery., PMID:40530451
Outcomes Following Transoral Laser Microsurgery for T1b and T2a Glottic Squamous Cell Carcinoma With and Without Anterior Commissure Involvement: A Retrospective Chart Review., PMID:40530452
Extreme Drought Decreases the Stability of Above- but Not Below-Ground Productivity Across Eurasian Steppes., PMID:40530453
From Consensus to Innovation: Advancing the Science of Eating-Disorder Measurement., PMID:40530454
Exploring the Role of Artificial Intelligence in Oral Pathology: Diagnostic and Prognostic Implications., PMID:40530456
Clinical forensic medical examinations conducted by the Department of Forensic Medicine in Copenhagen in child abuse cases., PMID:40530457
A Novel COL12A1 Mutation Causes Oral Tissue Abnormalities by Regulating Gingival Fibroblast Function., PMID:40530458
Efficacy and safety of thalidomide for oncology-related uses approved in Brazil: An overview of systematic reviews., PMID:40530461
Place of Death in Patients with Motor Neuron Disease and the Association with Comorbidities During the Coronavirus Disease 2019 Pandemic: A Population-Based Analysis., PMID:40530462
Lethal effects of allyl isothiocyanate on the egg masses of flighted spongy moth complex Lymantria dispar japonica (Lepidoptera: Erebidae)., PMID:40530467
4D Printing in Veterinarian Science: The Coming Technology., PMID:40530471
Educational Attainment Level and Risk of Mortality and Cardiopulmonary Outcomes in High-Risk Patients With Cardiovascular Disease: The INVESTED Trial., PMID:40530474
The Role of Elemental Factors in the Reactivity of Combination Reactions between Heavy Vinylidene-Like Molecules and Carbene Analogues., PMID:40530475
Preclinical Evaluation of a Growth-Accommodating Transcatheter Pulmonary Valve System for Young Children., PMID:40530477
Impact of Multiple Cardiovascular Events on Long-Term Outcomes and Bleeding Risk in Patients With Acute Coronary Syndrome: A Nationwide Population-Based Cohort Study., PMID:40530479
Transcatheter Aortic Valve Durability: Focus on Structural Valve Deterioration., PMID:40530490
Circ-myh8/KAT7 Affects PANoptosis in Pulmonary Arterial Smooth Muscle Cells: Involvement of Super-Enhancers in FOSL2 Expression., PMID:40530493
Hereditary Elliptocytosis Resulting From Heterozygosity for β Spectrin Tandil., PMID:40530495
The interleukin-1 family cytokines in psoriasis: pathogenetic role and therapeutic perspectives, PMID: 33538202
Target molecules for future hidradenitis suppurativa treatment, PMID: 34085329
Study protocol of the global Effisayil 1 Phase II, multicentre, randomised, double-blind, placebo-controlled trial of spesolimab in patients with generalized pustular psoriasis presenting with an acute flare, PMID: 33785490
Spesolimab: A Novel Treatment for Pustular Psoriasis, PMID: 32208020
Spesolimab, an Anti-Interleukin-36 Receptor Antibody, in Patients with Palmoplantar Pustulosis: Results of a Phase IIa, Multicenter, Double-Blind, Randomized, Placebo-Controlled Pilot Study, PMID: 33661508
Inhibition of the Interleukin-36 Pathway for the Treatment of Generalized Pustular Psoriasis, PMID: 30855749
Exploring the Role of IL-36 Cytokines as a New Target in Psoriatic Disease, PMID: 33919434
Diagnosis, Screening and Treatment of Patients with Palmoplantar Pustulosis (PPP): A Review of Current Practices and Recommendations, PMID: 32884319
For research use only. Not for human or drug use.
