Catalog No.
DHJ72801
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Humanized
Isotype
IgG1-kappa
Clonality
Monoclonal
Target
FIL1D, Interleukin-1 family member 5, IL-36Ra, IL1HY1, Interleukin-36 receptor antagonist protein, IL1RP3, IL-1RP3, IL-1ra homolog 1, Interleukin-1-like protein 1, IL-1-related protein 3, IL1L1, Interleukin-1 HY1, IL-1HY1, Interleukin-1 delta, FIL1 delta, IL-1 delta, IL-1L1, Interleukin-1 receptor antagonist homolog 1, IL36RN, IL1F5, IL-1F5
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9UBH0
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
BI 655130, BI655130, MAB92,CAS: 2097104-58-8
Clone ID
Spesolimab
Diagnosis, Screening and Treatment of Patients with Palmoplantar Pustulosis (PPP): A Review of Current Practices and Recommendations, PMID: 32884319
Exploring the Role of IL-36 Cytokines as a New Target in Psoriatic Disease, PMID: 33919434
Inhibition of the Interleukin-36 Pathway for the Treatment of Generalized Pustular Psoriasis, PMID: 30855749
Spesolimab, an Anti-Interleukin-36 Receptor Antibody, in Patients with Palmoplantar Pustulosis: Results of a Phase IIa, Multicenter, Double-Blind, Randomized, Placebo-Controlled Pilot Study, PMID: 33661508
Spesolimab: A Novel Treatment for Pustular Psoriasis, PMID: 32208020
Study protocol of the global Effisayil 1 Phase II, multicentre, randomised, double-blind, placebo-controlled trial of spesolimab in patients with generalized pustular psoriasis presenting with an acute flare, PMID: 33785490
Target molecules for future hidradenitis suppurativa treatment, PMID: 34085329
The interleukin-1 family cytokines in psoriasis: pathogenetic role and therapeutic perspectives, PMID: 33538202
Hereditary Elliptocytosis Resulting From Heterozygosity for β Spectrin Tandil., PMID:40530495
Circ-myh8/KAT7 Affects PANoptosis in Pulmonary Arterial Smooth Muscle Cells: Involvement of Super-Enhancers in FOSL2 Expression., PMID:40530493
Transcatheter Aortic Valve Durability: Focus on Structural Valve Deterioration., PMID:40530490
Impact of Multiple Cardiovascular Events on Long-Term Outcomes and Bleeding Risk in Patients With Acute Coronary Syndrome: A Nationwide Population-Based Cohort Study., PMID:40530479
Preclinical Evaluation of a Growth-Accommodating Transcatheter Pulmonary Valve System for Young Children., PMID:40530477
The Role of Elemental Factors in the Reactivity of Combination Reactions between Heavy Vinylidene-Like Molecules and Carbene Analogues., PMID:40530475
Educational Attainment Level and Risk of Mortality and Cardiopulmonary Outcomes in High-Risk Patients With Cardiovascular Disease: The INVESTED Trial., PMID:40530474
4D Printing in Veterinarian Science: The Coming Technology., PMID:40530471
Lethal effects of allyl isothiocyanate on the egg masses of flighted spongy moth complex Lymantria dispar japonica (Lepidoptera: Erebidae)., PMID:40530467
Place of Death in Patients with Motor Neuron Disease and the Association with Comorbidities During the Coronavirus Disease 2019 Pandemic: A Population-Based Analysis., PMID:40530462
Efficacy and safety of thalidomide for oncology-related uses approved in Brazil: An overview of systematic reviews., PMID:40530461
A Novel COL12A1 Mutation Causes Oral Tissue Abnormalities by Regulating Gingival Fibroblast Function., PMID:40530458
Clinical forensic medical examinations conducted by the Department of Forensic Medicine in Copenhagen in child abuse cases., PMID:40530457
Exploring the Role of Artificial Intelligence in Oral Pathology: Diagnostic and Prognostic Implications., PMID:40530456
From Consensus to Innovation: Advancing the Science of Eating-Disorder Measurement., PMID:40530454
Extreme Drought Decreases the Stability of Above- but Not Below-Ground Productivity Across Eurasian Steppes., PMID:40530453
Outcomes Following Transoral Laser Microsurgery for T1b and T2a Glottic Squamous Cell Carcinoma With and Without Anterior Commissure Involvement: A Retrospective Chart Review., PMID:40530452
Relevance of GDF15 as a biomarker for clinical outcomes after bariatric surgery., PMID:40530451
Field evaluation of an agricultural weed detector using YOLO image recognition: background conditions affect detection performance., PMID:40530444
Phenotype-specific dynamics of serum albumin and their impact on sepsis mortality., PMID:40530442
Immunomodulatory green nanomedicine production, tumor cellular targeting, in vivo biodistributions and preclinical therapeutic efficacy investigations of resveratrol-functionalized gold and theranostic 198gold nanoparticles., PMID:40530440
Desire for Sterilization Reversal in Delaware, US: The Roles of LARC Use, Personal Abortion Acceptability, and Economic Disadvantage., PMID:40530438
Relationships Between Nutrition Risk and Frailty in Candidates for Lung Transplant., PMID:40530437
Efficacy of Mesenchymal Stem Cells in the Treatment of Diabetic Foot Ulcers: A Meta-Analysis of Randomized Controlled Trials., PMID:40530428
Alleviation of myocardial infarction by hydrogen sulfide-releasing nanoparticles: mechanisms and therapeutic effects., PMID:40530426
Treatment outcomes of successful M1 versus M2 thrombectomy for low-ASPECTS stroke patients., PMID:40530425
Neodymium-modified Mg-Zn-Zr magnesium alloy as a biodegradable osteogenic implant., PMID:40530420
Adjuvant conditioning shapes the adaptive immune response promoting immunotolerance via NLRP3/interleukin-1., PMID:40530419
Exploring LLM-powered multi-session human-robot interactions with university students., PMID:40530417
A dual-targeting strategy to inhibit colorectal cancer liver metastasis via tumor cell ferroptosis and cancer-associated fibroblast reprogramming., PMID:40530415
Real-time magnetic resonance visualization of tumor acidosis as a precognition indicator of therapeutic efficacy., PMID:40530412
Exploring Psychedelics for Unmet Needs in Women's Reproductive Health., PMID:40530407
Fu's Subcutaneous Needling Combined with Kinematic Acupuncture versus Electroacupuncture in the Treatment of Cervical Spondylotic Radiculopathy: A Randomized Controlled Trial [Letter]., PMID:40530401
Effect of Locoregional Vs General Anesthesia on Incidence of Delayed Neurocognitive Recovery in Patients Undergoing Hip Fracture Surgery: A Randomized Controlled Trial., PMID:40530400
Exploring the potential of honokiol as a treatment for cardiovascular disease (Review)., PMID:40530396
Sudden Cardiac Arrest With Ventricular Fibrillation in a Patient With Epilepsy and a Vagus Nerve Stimulator., PMID:40530393
Black Women as Superwomen? The Mental Health Effects of Superwoman Schema, Socioeconomic Status, and Financial Strain., PMID:40530389
Targeting ApoE-KCC2 Signaling Rescues GABAergic Synaptic Dysfunction and Depression-like Behaviors in Mice., PMID:40530388
Sodium houttuyfonate inhibits the cariogenic virulence of Streptococcus mutans through the downregulation of VicRK two components pathway., PMID:40530386
Progress and challenges to TB elimination in New South Wales, Australia., PMID:40530385
Antenatal screening for TB disease: a systematic review and meta-analysis., PMID:40530378
Pharmacist-Driven Deprescribing to Reduce Anticholinergic Burden in Veterans With Dementia., PMID:40530371
Accounting for Withdrawal of Life-Sustaining Treatment in the Analysis of Traumatic Brain Injury Studies., PMID:40530366
Recent advances on the mechanism of acupuncture in the treatment of subjective tinnitus., PMID:40530363
Retrospective Analysis of Gut Microbiota and Metabolomic Profiles in Pregnant Women: Association with Cesarean Section Risk., PMID:40530360
Isolated Feet Edema in Turner Syndrome by Prenatal Ultrasonography - Case Report and Literature Review., PMID:40530359
Sex Hormone Levels and Pain Thresholds in the Luteal Phase of Healthy Women., PMID:40530358
Predicting transient performance of a heavy-duty gaseous-fuelled engine using combined phenomenological and machine learning models., PMID:40530355
Association between lactate dehydrogenase to albumin ratio and ICU mortality in patients with acute kidney injury: a retrospective cohort study., PMID:40530353
For research use only. Not for human or drug use.
