Catalog No.
RVV15401
Species reactivity
Epstein-Barr virus (strain B95-8) (HHV-4) (Human herpesvirus 4), Epstein-Barr virus (strain AG876) (HHV-4) (Human herpesvirus 4)
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
Envelope glycoprotein L, gL, BKRF2, Envelope glycoprotein H, gH, gH
Concentration
0.52 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P03212, Q1HVF6, P03231
Applications
ELISA, IF
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
E1D1
Structural basis for Epstein-Barr virus host cell tropism mediated by gp42 and gHgL entry glycoproteins. PMID: 27929061
Serum antibodies to periodontal bacteria. PMID: 2117654
Epstein-Barr virus lacking glycoprotein gp85 cannot infect B cells and epithelial cells. PMID: 11021994
The Epstein-Barr virus (EBV) BZLF2 gene product associates with the gH and gL homologs of EBV and carries an epitope critical to infection of B cells but not of epithelial cells. PMID: 7539502
Serum antibody reactive with predominant organisms in the subgingival flora of young adults with generalized severe periodontitis. PMID: 3988337
Co-expression of the Epstein-Barr virus BXLF2 and BKRF2 genes with a recombinant baculovirus produces gp85 on the cell surface with antigenic similarity to the native protein. PMID: 8847522
Identification of the gene encoding the Escherichia coli lipid A 4'-kinase. Facile phosphorylation of endotoxin analogs with recombinant LpxK. PMID: 9268317
Neutralizing antibodies against Epstein-Barr virus infection of B cells can protect from oral viral challenge in the rhesus macaque animal model. PMID: 34337567
Influence of dentin and enamel pretreatment with acidic sulfur compounds on adhesive performance. PMID: 23138454
Growth pattern and NGF-dependent survival of dorsal root ganglia neurons of distinct glyco-phenotype. PMID: 9485046
[A non-invasive quantitative measurement of cerebral blood flow using N-isopropyl-[123I]p-iodoamphetamine and single photon emission CT]. PMID: 1770653
Eph Receptor Tyrosine Kinases Are Functional Entry Receptors for Murine Gammaherpesvirus 68., PMID:40501621
High IgG titers against EBV glycoprotein 42 correlate with lower risk of nasopharyngeal carcinoma., PMID:39959976
Association Between Antibodies That Bind Epstein-Barr Virus (EBV) gp350 and gH/gL and Shedding of EBV in Saliva From Nasopharyngeal Carcinoma Multiplex Family Members in Taiwan., PMID:39229285
A gH/gL-encoding replicon vaccine elicits neutralizing antibodies that protect humanized mice against EBV challenge., PMID:38926438
Vaccination with nanoparticles displaying gH/gL from Epstein-Barr virus elicits limited cross-protection against rhesus lymphocryptovirus., PMID:38781964
Epstein-Barr virus gp42 antibodies reveal sites of vulnerability for receptor binding and fusion to B cells., PMID:38479361
Urgency and necessity of Epstein-Barr virus prophylactic vaccines., PMID:36494369
Epstein-Barr virus gH/gL has multiple sites of vulnerability for virus neutralization and fusion inhibition., PMID:36306784
Immunization with a self-assembling nanoparticle vaccine displaying EBV gH/gL protects humanized mice against lethal viral challenge., PMID:35705092
Antibody Generation and Immunogenicity Analysis of EBV gp42 N-Terminal Region., PMID:34960650
Immunization with Components of the Viral Fusion Apparatus Elicits Antibodies That Neutralize Epstein-Barr Virus in B Cells and Epithelial Cells., PMID:30979688
An Antibody Targeting the Fusion Machinery Neutralizes Dual-Tropic Infection and Defines a Site of Vulnerability on Epstein-Barr Virus., PMID:29669253
Inhibition of EBV-mediated membrane fusion by anti-gHgL antibodies., PMID:28939750
Structural basis for potent antibody-mediated neutralization of human cytomegalovirus., PMID:28783665
Scanning Mutagenesis of Human Cytomegalovirus Glycoprotein gH/gL., PMID:26656708
Human Cytomegalovirus gH/gL/gO Promotes the Fusion Step of Entry into All Cell Types, whereas gH/gL/UL128-131 Broadens Virus Tropism through a Distinct Mechanism., PMID:26085146
Fusion of Epstein-Barr virus with epithelial cells can be triggered by αvβ5 in addition to αvβ6 and αvβ8, and integrin binding triggers a conformational change in glycoproteins gHgL., PMID:21957301
Structure of a core fragment of glycoprotein H from pseudorabies virus in complex with antibody., PMID:21149698
Point mutations in EBV gH that abrogate or differentially affect B cell and epithelial cell fusion., PMID:17307213
Cell-surface expression of a mutated Epstein-Barr virus glycoprotein B allows fusion independent of other viral proteins., PMID:15583133
Epstein-Barr virus gH is essential for penetration of B cells but also plays a role in attachment of virus to epithelial cells., PMID:10864642
Epstein-Barr virus lacking glycoprotein gp42 can bind to B cells but is not able to infect., PMID:9420211
Epstein-Barr virus uses HLA class II as a cofactor for infection of B lymphocytes., PMID:9151859
The Epstein-Barr virus (EBV) BZLF2 gene product associates with the gH and gL homologs of EBV and carries an epitope critical to infection of B cells but not of epithelial cells., PMID:7539502
For research use only. Not for human or drug use.
