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Anti-PLSCR1 Polyclonal Antibody

Catalog #:   PHA43601 Specific References (20) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: O15162
Overview

Catalog No.

PHA43601

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human PLSCR1 (Met1-Trp318).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Mg(2+)-dependent nuclease,Erythrocyte phospholipid scramblase,PLSCR1,PL scramblase 1,Phospholipid scramblase 1,MmTRA1b,Ca(2+)-dependent phospholipid scramblase 1

Purification

Purified by antigen affinity column.

Accession

O15162

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • WESTERN BLOT
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with PLSCR1 antibody (PHA43601) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 37 kDa
    Observed MW: 37 kDa
References

PLSCR1 is a cell-autonomous defence factor against SARS-CoV-2 infection., PMID:37438530

Quantitative proteomics of differentiated primary bronchial epithelial cells from chronic obstructive pulmonary disease and control identifies potential novel host factors post-influenza A virus infection., PMID:36713229

Defining resistance and tolerance traits in Covid-19: towards a stratified medicine approach., PMID:35686910

Proteomic analysis of neutrophils in ANCA-associated vasculitis reveals a dysregulation in proteinase 3-associated proteins such as annexin-A1 involved in apoptotic cell clearance., PMID:31142442

Epigenome-wide association study of peripheral blood mononuclear cells in systemic lupus erythematosus: Identifying DNA methylation signatures associated with interferon-related genes based on ethnicity and SLEDAI., PMID:30301579

Development of a multiplexed tumor-associated autoantibody-based blood test for the detection of colorectal cancer., PMID:29074220

Prediction of response to remission induction therapy by gene expression profiling of peripheral blood in Japanese patients with microscopic polyangiitis., PMID:28569178

Phospholipid scramblase 1 amplifies anaphylactic reactions in vivo., PMID:28282470

Presence of an interferon signature in individuals who are anti-nuclear antibody positive lacking a systemic autoimmune rheumatic disease diagnosis., PMID:28245862

Comprehensive molecular profiling of the B7 family of immune-regulatory ligands in breast cancer., PMID:27622076

Phospholipid scramblase 1 is required for β2-glycoprotein I binding in hypoxia and reoxygenation-induced endothelial inflammation., PMID:26216936

Targeting interferon response genes sensitizes aromatase inhibitor resistant breast cancer cells to estrogen-induced cell death., PMID:25588716

Antibody against N-terminal domain of phospholipid scramblase 1 induces apoptosis in colorectal cancer cells through the intrinsic apoptotic pathway., PMID:24766818

Blockade of phospholipid scramblase 1 with its N-terminal domain antibody reduces tumorigenesis of colorectal carcinomas in vitro and in vivo., PMID:23259795

Phospholipid scramblase 1 expression is enhanced in patients with antiphospholipid syndrome., PMID:22526829

Phospholipid scramblase 1 regulates Toll-like receptor 9-mediated type I interferon production in plasmacytoid dendritic cells., PMID:22453241

Phospholipid scramblase 1 is secreted by a lipid raft-dependent pathway and interacts with the extracellular matrix protein 1 in the dermal epidermal junction zone of human skin., PMID:20870722

Proteinase 3, the Wegener autoantigen, is externalized during neutrophil apoptosis: evidence for a functional association with phospholipid scramblase 1 and interference with macrophage phagocytosis., PMID:17712045

Phospholipid flip-flop and phospholipid scramblase 1 (PLSCR1) co-localize to uropod rafts in formylated Met-Leu-Phe-stimulated neutrophils., PMID:14766753

IgE receptor type I-dependent tyrosine phosphorylation of phospholipid scramblase., PMID:11259432

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Anti-PLSCR1 Polyclonal Antibody [PHA43601]
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