Catalog No.
PHA18301
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human WNT10B (Glu30-Pro322).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
WNT10B,WNT12,Protein Wnt-12,Protein Wnt-10b
Purification
Purified by antigen affinity column.
Accession
O00744
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Adiponectin negatively regulates pigmentation, Wnt/β-catenin and HGF/c-Met signalling within human scalp hair follicles ex vivo., PMID:34854998
Neutralization of oxidized phospholipids attenuates age-associated bone loss in mice., PMID:34278710
Dermal Adipose Tissue Secretes HGF to Promote Human Hair Growth and Pigmentation., PMID:33493531
CTLA-4Ig Improves Hyperalgesia in a Mouse Model of Osteoporosis., PMID:33322156
RANKL, Ephrin-Eph and Wnt10b are key intercellular communication molecules regulating bone remodeling in autologous transplanted goldfish scales., PMID:29886255
Neutralization of CD40 ligand costimulation promotes bone formation and accretion of vertebral bone mass in mice., PMID:29522194
CTLA-4Ig (abatacept) balances bone anabolic effects of T cells and Wnt-10b with antianabolic effects of osteoblastic sclerostin., PMID:29500936
Anti-CXCL4 monoclonal antibody accelerates telogen to anagen transition and attenuates apoptosis of the hair follicle in mice., PMID:28810552
Cytokine and hormonal regulation of bone marrow immune cell Wnt10b expression., PMID:28800644
CD8+ T cells mediate the regenerative PTH effect in hPDL cells via Wnt10b signaling., PMID:28071181
Low-magnitude, high-frequency vibration promotes the adhesion and the osteogenic differentiation of bone marrow-derived mesenchymal stem cells cultured on a hydroxyapatite-coated surface: The direct role of Wnt/β-catenin signaling pathway activation., PMID:28026000
Disruption of c-Kit Signaling in Kit(W-sh/W-sh) Growing Mice Increases Bone Turnover., PMID:27527615
Wnt/β-catenin signaling pathway activates melanocyte stem cells in vitro and in vivo., PMID:27138625
Hoxc8 initiates an ectopic mammary program by regulating Fgf10 and Tbx3 expression and Wnt/β-catenin signaling., PMID:26459221
Directed Differentiation of Human Embryonic Stem Cells into Prostate Organoids In Vitro and its Perturbation by Low-Dose Bisphenol A Exposure., PMID:26222054
CTLA-4Ig-induced T cell anergy promotes Wnt-10b production and bone formation in a mouse model., PMID:24757150
Enhanced immunoprotective effects by anti-IL-17 antibody translates to improved skeletal parameters under estrogen deficiency compared with anti-RANKL and anti-TNF-α antibodies., PMID:24677326
The sclerostin-independent bone anabolic activity of intermittent PTH treatment is mediated by T-cell-produced Wnt10b., PMID:24357520
Inducible brown adipose tissue, or beige fat, is anabolic for the skeleton., PMID:23696565
Autocrine stimulation of osteoblast activity by Wnt5a in response to TNF-α in human mesenchymal stem cells., PMID:23266365
Hepatic stellate cell-derived delta-like homolog 1 (DLK1) protein in liver regeneration., PMID:22298767
Comparison of the biological response of osteoblasts after tension and compression., PMID:21402736
Hepatitis C virus core protein activates Wnt/β-catenin signaling through multiple regulation of upstream molecules in the SMMC-7721 cell line., PMID:21340743
Regulation of bone formation by osteoclasts involves Wnt/BMP signaling and the chemokine sphingosine-1-phosphate., PMID:19075223
Activation of Wnt/beta-catenin pathway mediates growth and survival in B-cell progenitor acute lymphoblastic leukaemia., PMID:17614820
Cross-talk of WNT and FGF signaling pathways at GSK3beta to regulate beta-catenin and SNAIL signaling cascades., PMID:16940750
Wnt ligand expression in malignant melanoma: pilot study indicating correlation with histopathological features., PMID:14514922
Wnt and frizzled receptors as potential targets for immunotherapy in head and neck squamous cell carcinomas., PMID:12242657
For research use only. Not for human or drug use.
