Catalog No.
RGK08102
Host species
Mouse
Isotype
IgG1, kappa
Clonality
Monoclonal
Target
Hypusine, PubChem: 65396
Concentration
4.8 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
PubChem: 65396
Applications
DB, ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
Hpu98.61
Development of a reliable, sensitive, and convenient assay for the discovery of new eIF5A hypusination inhibitors., PMID:39937781
Novel deoxyhypusine synthase (DHPS) inhibitors target hypusination-induced vasculogenic mimicry (VM) against malignant melanoma., PMID:39393437
DHPS-Mediated Hypusination Regulates METTL3 Self-m6A-Methylation Modification to Promote Melanoma Proliferation and the Development of Novel Inhibitors., PMID:38952061
eIF5A inhibition influences T cell dynamics in the pancreatic microenvironment of the humanized mouse model of Type 1 Diabetes., PMID:30733517
Structural Analysis and Optimization of Context-Independent Anti-Hypusine Antibodies., PMID:26778617
Bifunctional activity of deoxyhypusine synthase/hydroxylase from Trichomonas vaginalis., PMID:26410361
Blocking eIF5A modification in cervical cancer cells alters the expression of cancer-related genes and suppresses cell proliferation., PMID:24220243
Characterization of a novel polyclonal anti-hypusine antibody., PMID:24024105
Mass spectrometrical analysis of bilin-binding protein from the wing of Hebomoia glaucippe (Linnaeus, 1758) (Lepidoptera: Pieridae)., PMID:22740467
Translation initiation factor eIF-5A, the hypusine-containing protein, is phosphorylated on serine and tyrosine and O-glycosylated in Trichomonas vaginalis., PMID:22212642
Identification of two novel Trichomonas vaginalis eif-5a genes., PMID:20060503
The N-terminal region of eukaryotic translation initiation factor 5A signals to nuclear localization of the protein., PMID:17707773
Cloning, expression and functional activity of deoxyhypusine synthase from Plasmodium vivax., PMID:17042947
Inhibition of multidrug-resistant HIV-1 by interference with cellular S-adenosylmethionine decarboxylase activity., PMID:16941339
Eukaryotic initiation factor 5A-1 (eIF5A-1) as a diagnostic marker for aberrant proliferation in intraepithelial neoplasia of the vulva., PMID:15262146
Higher activity of recombinant bovine deoxyhypusine synthase vs. human deoxyhypusine synthase., PMID:15039063
Subcellular localization of the hypusine-containing eukaryotic initiation factor 5A by immunofluorescent staining and green fluorescent protein tagging., PMID:12210765
Inhibition of CD83 cell surface expression during dendritic cell maturation by interference with nuclear export of CD83 mRNA., PMID:10790432
Nuclear pore localization and nucleocytoplasmic transport of eIF-5A: evidence for direct interaction with the export receptor CRM1., PMID:10381392
Synthesis of reagents for the construction of hypusine and deoxyhypusine peptides and their application as peptidic antigens., PMID:9748364
Deoxyhypusine synthase from rat testis: purification and characterization., PMID:7721768
Translation initiation factor eIF-5A, the hypusine-containing protein, is phosphorylated on serine in Saccharomyces cerevisiae., PMID:8325852
Detection of the hypusine-containing protein (HP = eIF-5A) in crude yeast extracts by two-dimensional western blots., PMID:1281091
Differential expression of genes encoding the hypusine-containing translation initiation factor, eIF-5A, in tobacco., PMID:1542563
Polyamines and their derivatives as modulators in growth and differentiation., PMID:2697982
cDNA and derived amino acid sequence of the hypusine containing protein from Dictyostelium discoideum., PMID:2540042
For research use only. Not for human or drug use.
