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Anti-MEN1 Polyclonal Antibody

Catalog #:   PHA07201 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: O00255
Overview

Catalog No.

PHA07201

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human MEN1 (Ser224-Pro395).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

MEN1,Menin,SCG2

Purification

Purified by antigen affinity column.

Accession

O00255

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • WESTERN BLOT
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with MEN1 antibody (PHA07201) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 22 kDa
    Observed MW: 22 kDa
References

Immunohistochemical Glucagon-like Peptide-1 Receptor Expression in Human Insulinomas., PMID:37894845

Thymic atypical carcinoid tumors with elevated mitotic counts in a patient with multiple endocrine neoplasia: A case report., PMID:36941083

Acromegaly caused by a GHRH-producing pancreatic neuroendocrine tumor: a rare manifestation of MEN1 syndrome., PMID:35199646

[Morphological characteristics of pituitary adenomas in the phenocopy of multiple endocrine neoplasia type 1]., PMID:35018761

A case report of multiple endocrine neoplasia type 1 and autoimmune disease: Coincidence or correlation?, PMID:34889280

The LEDGF/p75 Integrase Binding Domain Interactome Contributes to the Survival, Clonogenicity, and Tumorsphere Formation of Docetaxel-Resistant Prostate Cancer Cells., PMID:34685704

Identification of novel autoantibodies based on the protein chip encoded by cancer-driving genes in detection of esophageal squamous cell carcinoma., PMID:33457096

B7 immune-checkpoints as targets for the treatment of neuroendocrine tumors., PMID:33410766

Differentiated thyroid carcinoma in sporadic and familial presentations of acromegaly: A case series., PMID:32822652

Current and emerging therapies for PNETs in patients with or without MEN1., PMID:29449689

EXPRESSION OF MENIN IN THE HUMAN THYROID GLAND., PMID:31149167

Menin mediates Tat-induced neuronal apoptosis in brain frontal cortex of SIV-infected macaques and in Tat-treated cells., PMID:28178646

Loss of menin in osteoblast lineage affects osteocyte-osteoclast crosstalk causing osteoporosis., PMID:28106886

Silent subtype 3 pituitary adenomas are not always silent and represent poorly differentiated monomorphous plurihormonal Pit-1 lineage adenomas., PMID:26743473

Menin immunoreactivity in secretory granules of human pancreatic islet cells., PMID:25153502

Management of endocrine disease: a clinical update on tumor-induced hypoglycemia., PMID:24459236

A novel atypical presentation of insulin autoimmune syndrome (Hirata's disease) in a child., PMID:23843578

Proliferation rates of multiple endocrine neoplasia type 1 (MEN1)-associated tumors., PMID:23024266

[The role and mechanism of high expression of cyclin B2 in MEN1 insulinoma]., PMID:22193451

Epitope selection to male specific antigens for sex selection in swine., PMID:21397337

MEN1 in pancreatic endocrine tumors: analysis of gene and protein status in 169 sporadic neoplasms reveals alterations in the vast majority of cases., PMID:20566584

Unusual clinical and pathological presentation of a neuroendocrine tumor in a patient with multiple endocrine neoplasia type 1., PMID:19564705

Decreased expression and promoter methylation of the menin tumor suppressor in pancreatic ductal adenocarcinoma., PMID:19170121

MEN1 missense mutations impair sensitization to apoptosis induced by wild-type menin in endocrine pancreatic tumor cells., PMID:18775714

Tumour suppressor menin is essential for development of the pancreatic endocrine cells., PMID:18772165

Loss of membrane localization and aberrant nuclear E-cadherin expression correlates with invasion in pancreatic endocrine tumors., PMID:18300809

Novel association of duodenal gastrinoma and atrophic gastritis: case report and literature review., PMID:18194935

Blocking vascular endothelial growth factor-A inhibits the growth of pituitary adenomas and lowers serum prolactin level in a mouse model of multiple endocrine neoplasia type 1., PMID:18172277

Tacrolimus-related polyneuropathy: case report and review of the literature., PMID:18055100

Carcinogenic hypergastrinemia: signet-ring cell carcinoma in a patient with multiple endocrine neoplasia type 1 with Zollinger-Ellison's syndrome., PMID:17609302

Increased gastric expression of MMP-7 in hypergastrinemia and significance for epithelial-mesenchymal signaling., PMID:17218472

Establishment and characterization of cell lines from three human thyroid carcinomas: responses to all-trans-retinoic acid and mutations in the BRAF gene., PMID:17134824

Tumor suppressor menin: the essential role of nuclear localization signal domains in coordinating gene expression., PMID:16449969

Ghrelin expression in neuroendocrine tumours of the gastrointestinal tract with multiple endocrine neoplasia type 1., PMID:16278790

Differential expression of menin in sporadic pituitary adenomas., PMID:15163308

Frequent overexpression of cyclin D1 in sporadic pancreatic endocrine tumours., PMID:14529567

Menin, a tumor suppressor, associates with nonmuscle myosin II-A heavy chain., PMID:14508515

In situ analysis of human menin in normal and neoplastic pancreatic tissues: evidence for differential expression in exocrine and endocrine cells., PMID:12915685

Proangiogenic properties of human myeloma cells: production of angiopoietin-1 and its potential relationship to myeloma-induced angiogenesis., PMID:12649156

A case of multicentric gastric carcinoids without hypergastrinemia., PMID:12510233

The 32-kilodalton subunit of replication protein A interacts with menin, the product of the MEN1 tumor suppressor gene., PMID:12509449

Potential role of the angiopoietin/tie2 system in ischemia-induced retinal neovascularization., PMID:12506101

Isolation of precursor endothelial cells from peripheral blood for donor-specific crossmatching before organ transplantation., PMID:12490778

Angiopoietin-1 and angiopoietin-2 share the same binding domains in the Tie-2 receptor involving the first Ig-like loop and the epidermal growth factor-like repeats., PMID:12427764

Increased fibroblast growth factor-like autoantibodies in serum from a subset of patients with cancer-associated hypercalcemia., PMID:12384179

Menin's interaction with glial fibrillary acidic protein and vimentin suggests a role for the intermediate filament network in regulating menin activity., PMID:12169273

NERF2, a member of the Ets family of transcription factors, is increased in response to hypoxia and angiopoietin-1: a potential mechanism for Tie2 regulation during hypoxia., PMID:11967990

Production and characterization of a Tie2 agonist monoclonal antibody., PMID:11824375

Angiopoietin 2 stimulates migration and tube-like structure formation of murine brain capillary endothelial cells through c-Fes and c-Fyn., PMID:11801735

Differential expression of menin in various adrenal tumors. The role of menin in adrenal tumors., PMID:11745215

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-MEN1 Polyclonal Antibody [PHA07201]
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