Catalog No.
PHA04301
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human LGALS9 (Met1-Gln148).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Ecalectin,LGALS9,Galectin-9,Gal-9,Tumor antigen HOM-HD-21
Purification
Purified by antigen affinity column.
Accession
O00182
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Adaptive-like NK cell responses to influenza correlate with humoral immunity and are influenced by age and sex., PMID:40501653
Dynamic analysis of intrahepatic T cells reveals a unique group of restorative Cxcr3+ tissue-resident CD4 T cells in acute liver injury., PMID:39828240
Galectin 9 rescues the inducibility of IL-10 expression in regulatory B cells of patients with food allergy., PMID:39747510
Immunomodulation by galectin-9: Distinct role in T cell populations, current therapeutic avenues and future potential., PMID:39571310
Cell-autonomous targeting of arabinogalactan by host immune factors inhibits mycobacterial growth., PMID:39495223
Monocyte-derived Galectin-9 and PD-L1 differentially impair adaptive and innate immune response in chronic HBV infection and their expression remain unaltered after antiviral therapy., PMID:39445017
[Research progress on T-cell immunoglobulin mucin 3/galectin 9 (TIM-3/galectin-9) in tumour immunity]., PMID:39215674
Enhanced expression of galectin-9 in triple negative breast cancer cells following radiotherapy: Implications for targeted therapy., PMID:39077999
In chronic spontaneous urticaria, increased Galectin-9 expression on basophils and eosinophils is linked to high disease activity, endotype-specific markers, and response to omalizumab treatment., PMID:39021347
Expression of Intracellular Galectin-8 and -9 in Endometrial Cancer., PMID:39000016
A novel anti-galectin-9 immunotherapy limits the early progression of pancreatic neoplastic lesions in transgenic mice., PMID:38098486
A spatially resolved timeline of the human maternal-fetal interface., PMID:37468587
Increased Galectin-9 Levels Correlate with Disease Activity in Patients with DMARD-Naïve Rheumatoid Arthritis and Modulate the Secretion of MCP-1 and IL-6 from Synovial Fibroblasts., PMID:36672263
Contribution of the TIM-3/Gal-9 immune checkpoint to tropical parasitic diseases., PMID:36509129
The Correlation of Ten Immune Checkpoint Gene Expressions and Their Association with Gastric Cancer Development., PMID:36430322
Galectin-9 contributes to the pathogenesis of atopic dermatitis via T cell immunoglobulin mucin-3., PMID:35967337
A new emerging target in cancer immunotherapy: Galectin-9 (LGALS9)., PMID:37554219
Revealing the Immune Heterogeneity between Systemic Lupus Erythematosus and Rheumatoid Arthritis Based on Multi-Omics Data Analysis., PMID:35563556
Development and characterization of anti-galectin-9 antibodies that protect T cells from galectin-9-induced cell death., PMID:35283189
Obesity-induced galectin-9 is a therapeutic target in B-cell acute lymphoblastic leukemia., PMID:35241678
Galectin-9 mediates neutrophil capture and adhesion in a CD44 and β2 integrin-dependent manner., PMID:34847625
Chemoradiation induces upregulation of immunogenic cell death-related molecules together with increased expression of PD-L1 and galectin-9 in gastric cancer., PMID:34112882
THE ROLE OF GALECTIN-9 IN PATIENTS WITH CHRONIC VIRAL HEPATITIS C AND ITS CONNECTION WITH THE TYPE OF THERAPY, THE DEGREE OF FIBROSIS, CLINICAL, LABORATORY, AUTOIMMUNE AND INTEGRATIVE INDICATORS., PMID:34090287
High Levels of the Cleaved Form of Galectin-9 and Osteopontin in the Plasma Are Associated with Inflammatory Markers That Reflect the Severity of COVID-19 Pneumonia., PMID:34067072
Expression and Prognostic Value of the Immune Checkpoints Galectin-9 and PD-L1 in Glioblastomas., PMID:33990845
Serial transplantation unmasks galectin-9 contribution to tumor immune escape in the MB49 murine model., PMID:33664349
Galectin-9 interacts with PD-1 and TIM-3 to regulate T cell death and is a target for cancer immunotherapy., PMID:33547304
Galectin-9 regulates follicular helper T cells to inhibit humoral autoimmunity-induced pulmonary fibrosis., PMID:33316546
Galectin-9 expression defines exhausted T cells and impaired cytotoxic NK cells in patients with virus-associated solid tumors., PMID:33310773
Galectin-9 bridges human B cells to vascular endothelium while programming regulatory pathways., PMID:33285511
Increased serum levels of galectin-9 in patients with chikungunya fever., PMID:32565125
Galectin-9 expression as a poor prognostic factor in patients with renal cell carcinoma., PMID:32424467
Differential regulation and correlation between galectin-9 and anti-CCP antibody (ACPA) in rheumatoid arthritis patients., PMID:32293530
Endothelial and Inflammation Biomarker Profiles at Diagnosis Reflecting Clinical Heterogeneity and Serving as a Prognostic Tool for Treatment Response in Two Independent Cohorts of Patients With Juvenile Dermatomyositis., PMID:32103637
Soluble T cell immunoglobulin mucin domain 3 (sTim-3) in maternal sera: a potential contributor to immune regulation during pregnancy., PMID:32019363
Possible therapeutic applicability of galectin-9 in cutaneous T-cell lymphoma., PMID:31787505
Galectin-1-driven T cell exclusion in the tumor endothelium promotes immunotherapy resistance., PMID:31710313
Aspergillus fumigatus enhances human NK cell activity by regulating M1 macrophage polarization., PMID:31173233
N-Linked Glycosylation Regulates CD22 Organization and Function., PMID:31019513
Tim-3 regulates inflammatory cytokine expression and Th17 cell response induced by monocytes from patients with chronic hepatitis B., PMID:30729555
Plasma Galectin-9 Concentrations in Normal and Diseased Condition., PMID:30396167
Secreted IgD Amplifies Humoral T Helper 2 Cell Responses by Binding Basophils via Galectin-9 and CD44., PMID:30291028
Characterization of neutralizing antibodies reacting with the 213-224 amino-acid segment of human galectin-9., PMID:30204750
Galectin-9 is an easy to measure biomarker for the interferon signature in systemic lupus erythematosus and antiphospholipid syndrome., PMID:30185417
Endogenous Galectin-9 Suppresses Apoptosis in Human Rheumatoid Arthritis Synovial Fibroblasts., PMID:30150656
Galectin-9 binds IgM-BCR to regulate B cell signaling., PMID:30120235
Galectin-9 suppresses B cell receptor signaling and is regulated by I-branching of N-glycans., PMID:30120234
Immunosuppression of Human Adipose-Derived Stem Cells on T Cell Subsets via the Reduction of NF-kappaB Activation Mediated by PD-L1/PD-1 and Gal-9/TIM-3 Pathways., PMID:29978730
Soluble galectin 9 potently enhanced regulatory T-cell formation, a pathway impaired in patients with intracranial aneurysm., PMID:29978574
Galectin-9 inhibits TLR7-mediated autoimmunity in murine lupus models., PMID:29611821
For research use only. Not for human or drug use.
