Cargo of small extracellular vesicles from neuronal origin shows progression of dementia in individuals with Down syndrome., PMID:40524460
Immunohistochemical evaluation of a trial of gantenerumab or solanezumab in dominantly inherited Alzheimer disease., PMID:40459787
Fluid biomarkers in atypical Parkinsonism: current state and future perspectives., PMID:40392273
Supramolecular Copolymerization of Glycopeptide Amphiphiles and Amyloid Peptides Improves Neuron Survival., PMID:40365999
High precision and cost-effective multiplex quantification of amyloid-β40, amyloid-β42, p181Tau, p217Tau, neurofilament light chain, and glial fibrillary acidic protein from plasma and serum., PMID:40356374
Stamp-Imprinted Polymer EIS Biosensor for Amyloid-Beta Detection: A Novel Approach Towards Alzheimer's Screening., PMID:40277542
ACE-dependent Alzheimer's disease: Further assessment of the impact of ACE mutations on blood ACE levels., PMID:40164395
Amyloid-β-regulated gene circuits for programmable Alzheimer's disease therapy., PMID:40161792
Multianalyte Nanopore Detection of Alzheimer's Biomarkers: A Label-Free Platform with Improved Sensitivity and Range., PMID:40129019
Identification of the binding site and immunoreactivity of anti-Aβ antibody 11A1: Comparison with the toxic conformation-specific TxCo-1 antibody., PMID:40120343
Influence of apolipoprotein E genotype on the proteomic profile in cerebral microdialysis after human severe traumatic brain injury: a prospective observational study., PMID:40109561
Association between amyloid-β42 levels and neuropsychiatric symptoms in Alzheimer's disease trials., PMID:40046340
Utilizing Functionalized Dual-Microbead Interfaces for Measurements of Amyloid-beta (1-42) with Femtomolar Sensitivity., PMID:39993947
Associations of Cerebrospinal Fluid Orexin-A, Alzheimer Disease Biomarkers, and Cognitive Performance., PMID:39957622
Olfactory deprivation promotes amyloid β deposition in a mouse model of Alzheimer's disease., PMID:39922408
Biomarker treatment effects in two phase 3 trials of gantenerumab., PMID:39887500
Mapping of Amyloid-β Aggregates In Vivo by a Fluorescent Probe with Dual Recognition Moieties., PMID:39873275
Longitudinally persisting KCNA2-autoantibodies in mild amnestic dementia with Alzheimer´s pathology - Report and literature review., PMID:39855473
Multi-Targeting Macrocyclic Peptides as Nanomolar Inhibitors of Self- and Cross-Seeded Amyloid Self-Assembly of α-Synuclein., PMID:39822034
A colorimetric nano-enzyme assay with Ni@Pt nanoparticles as signal labels for rapid and sensitive detection of exosomal Aβ42 in plasma., PMID:39753867
Brain MRI volumetry and atrophy rating scales as predictors of amyloid status and eligibility for anti-amyloid treatment in a real-world memory clinic setting., PMID:39708177
Alzheimer's disease-associated CD83(+) microglia are linked with increased immunoglobulin G4 and human cytomegalovirus in the gut, vagal nerve, and brain., PMID:39698934
Amyloid-β and phosphorylated tau screening in bottlenose dolphin (Tursiops truncatus) and striped dolphin (Stenella coeruleoalba) brains from Italy reveals distinct immunohistochemical patterns correlating with age and co-morbidity., PMID:39591474
Amyloid-Related Imaging Abnormalities (ARIA) in Clinical Trials of Gantenerumab in Early Alzheimer Disease., PMID:39556389
Ultrasensitive Detection of Blood-Based Alzheimer's Disease Biomarkers: A Comprehensive SERS-Immunoassay Platform Enhanced by Machine Learning., PMID:39537190
[Possibility of short synthetic peptides with activities of suppressing amyloid β aggregation and resolving its aggregated form as therapeutic drugs for Alzheimer's disease]., PMID:39496417
Molecular Mechanisms Underlying Amyloid Beta Peptide Mediated Upregulation of Vascular Cell Adhesion Molecule-1 in Alzheimer Disease., PMID:39455283
Morphological and Molecular Profiling of Amyloid-β Species in Alzheimer's Pathogenesis., PMID:39446217
Early divergent modulation of NLRP2's and NLRP3's inflammasome sensors vs. AIM2's one by signals from Aβ·Calcium-sensing receptor complexes in human astrocytes., PMID:39426463
Safety, tolerability, pharmacokinetics and pharmacodynamics of a single intravenous dose of SHR-1707 in healthy adult subjects: two randomized, double-blind, single-ascending-dose, phase 1 studies., PMID:39390616
Performance of Plasma Biomarkers Combined with Structural MRI to Identify Candidate Participants for Alzheimer's Disease-Modifying Therapy., PMID:39350364
MEDI1814 selectively reduces free Aβ42 in cerebrospinal fluid of non-clinical species and Alzheimer's disease patients., PMID:39319998
Increases in amyloid-β42 slow cognitive and clinical decline in Alzheimer's disease trials., PMID:39259179
Glia maturation factor-γ regulates amyloid-β42 phagocytosis through scavenger receptor class A type I in murine macrophages., PMID:39243388
Efficient characterization of multiple binding sites of small molecule imaging ligands on amyloid-beta, tau and alpha-synuclein., PMID:38953933
Crystal Violet Selectively Detects Aβ Oligomers but Not Fibrils In Vitro and in Alzheimer's Disease Brain Tissue., PMID:38927020
Lecanemab demonstrates highly selective binding to Aβ protofibrils isolated from Alzheimer's disease brains., PMID:38906341
Disease modifying effects of the amyloid-beta protofibril-selective antibody mAb158 in aged Tg2576 transgenic mice., PMID:38901655
Aβ42 and ROS dual-targeted multifunctional nanocomposite for combination therapy of Alzheimer's disease., PMID:38783363
Quantitative systems pharmacology-based exploration of relevant anti-amyloid therapy challenges in clinical practice., PMID:38774587
Recalibrating the Risk-Benefit Profiles of Lecanemab and Donanemab: Scales, Immunoreactivity, and Changes in Amyloid-β42., PMID:38701151
Effect of Regulation of Chemerin/Chemokine-like Receptor 1/Stimulator of Interferon Genes Pathway on Astrocyte Recruitment to Aβ Plaques., PMID:38673909
Dual sensitivity-enhanced microring resonance-based integrated microfluidic biosensor for Aβ42 detection., PMID:38657362
Divergent Age-Dependent Conformational Rearrangement within Aβ Amyloid Deposits in APP23, APPPS1, and AppNL-F Mice., PMID:38652895
Generation and Study of Antibodies against Two Triangular Trimers Derived from Aβ., PMID:38644932
Label-free detection of Aβ-42: a liquid crystal droplet approach for Alzheimer's disease diagnosis., PMID:38628477
Ultrathin Parylene C-based sensitivity-gain nanoplasmonic sensor integrated on VCSEL for Aβ42 detection., PMID:38518564
Disease staging of Alzheimer's disease using a CSF-based biomarker model., PMID:38514824
Comparison of cerebrospinal fluid, plasma and neuroimaging biomarker utility in Alzheimer's disease., PMID:38505230
For research use only. Not for human or drug use.
