Catalog No.
                        FHD67210
                        
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            Species reactivity
                        
                        Human                        
                                                
                                            Host species
                        
                        Human                        
                                                
                                            Isotype
                        
                        IgG1, kappa                        
                                                
                                            Clonality
                        
                        Monoclonal                        
                                                
                                            
                                            Conjugation
                        
                        Unconjugated                        
                                                
                                            
                                            Target
                        
                        APT1, TNFRSF6, FAS1, FASLG receptor, CD95, Apo-1 antigen, Tumor necrosis factor receptor superfamily member 6, FAS, Apoptosis-mediating surface antigen FAS                        
                                                
                                            
                                            Concentration
                        
                        1 mg/ml                        
                                                
                                            Endotoxin level
                        
                        Please contact with the lab for this information.                        
                                                
                                            Purity
                        
                        >95% as determined by SDS-PAGE.                        
                                                
                                            Purification
                        
                        Protein A/G purified from cell culture supernatant.                        
                                                
                                            Accession
                        
                        P25445                        
                                                
                                            
                                            Applications
                        
                        FCM                        
                                                
                                            Form
                        
                        Liquid                        
                                                
                                            Storage buffer
                        
                        0.01M PBS, pH 7.4.                        
                                                
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            Stability and Storage
                        
                        Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.                        
                                                
                                            
                                            
                                                Clone ID
                            SAA0040
                            
                                                    
                                            
                                            
                                        
                 
                
                
                                            Phosphatidylglucoside regulates apoptosis of human neutrophilic lineage cells., PMID:40496860
                                            Circulating immunoregulatory B cell and autoreactive antibody profiles predict lack of toxicity to anti-PD-1 checkpoint inhibitor treatment in advanced melanoma., PMID:40449958
                                            Actionable heterogeneity of hepatocellular carcinoma therapy-induced senescence., PMID:40374812
                                            FAS mediates apoptosis, inflammation, and treatment of pathogen infection., PMID:40330016
                                            Single molecule recognition of CD95 receptors on the surface of HepG2 cells under the curcumin., PMID:40300310
                                            Dengue Viral Infection Induces Alteration of CD95 Expression in B Cell Subsets with Potential Involvement of Dengue Viral Non-Structural Protein 1., PMID:40284984
                                            CD73low B-cell phenotypes and distinct cytokine profiles in patients with active anti-Jo-1 antibody positive idiopathic inflammatory myopathies., PMID:40210261
                                            Distinct type 1 immune networks underlie the severity of restrictive lung disease after COVID-19., PMID:40140496
                                            Coordination of Neutrophil and Apoptosis-Inducing Ligand in Inflammatory Diseases., PMID:40099000
                                            T cell receptor usage and epitope specificity amongst CD8+ and CD4+ SARS-CoV-2-specific T cells., PMID:40092978
                                            Deep profiling of B cells responding to various pathogens uncovers compartments in IgG memory B cell and antibody-secreting lineages., PMID:39970201
                                            Spatially Resolved, Multiregion Proteomics for Prediction of Immunotherapy Outcome in Deficient Mismatch Repair Metastatic Colorectal Cancer., PMID:39969975
                                            Neutralizing IL-15 Inhibits Tissue-Damaging Immune Response in Ex Vivo Cultured Untreated Celiac Intestinal Mucosa., PMID:39937025
                                            [Effects of occupational lead exposure on the indicators of immune function of workers]., PMID:39909595
                                            An engineered palivizumab IgG2 subclass for synthetic gp130 and fas-mediated signaling., PMID:39828098
                                            Identification of B Cell Subpopulations with Pro- and Anti-Tumorigenic Properties in an Immunocompetent Mouse Model of Head and Neck Squamous Cell Carcinoma., PMID:39791721
                                            Cervical Cancer Cells Use the CD95 and IL-2 Pathways to Promote Their Proliferation and Survival., PMID:39766250
                                            The Role of TNF Receptor-Associated Factor 5 in the Formation of Germinal Centers by B Cells During the Primary Phase of the Immune Response in Mice., PMID:39596396
                                            Arthritis progressors have a decreased frequency of circulating autoreactive T cells during the at-risk phase of rheumatoid arthritis., PMID:39557489
                                            In vivo analysis of CRISPR-edited germinal center murine B cells., PMID:39483469
                                            Differences in phenotype between long-lived memory B cells against Plasmodium falciparum merozoite antigens and variant surface antigens., PMID:39466842
                                            Transient-resting culture after activation enhances the generation of CD8+ stem cell-like memory T cells from peripheral blood mononuclear cells., PMID:39357466
                                            A Novel Tetravalent CD95/Fas Fusion Protein With Superior CD95L/FasL Antagonism., PMID:39219154
                                            Immunological insights: assessing immune parameters in medical professionals exposed to SARS-CoV-2., PMID:39187767
                                            Diversity of Memory CD8+ T Cells in Tumor-Draining Lymph Nodes from Patients with Bladder Cancer., PMID:39184818
                                            The development of anti-PD-1 antibody-induced spinal cord injury in bone marrow transplant C57BL/6 Rag1-/- mouse model., PMID:39115961
                                            Features of the immune system and levels of blood transport components in residents of the arctic of the Russian Federation., PMID:39032081
                                            Nematode Galectin Inhibits Basophilic Leukaemia RBL-2H3 Cells Apoptosis in IgE-Mediated Activation., PMID:39000527
                                            Adaptive post-COVID-19 immune response in female subjects of the Russian arctic region., PMID:38989746
                                            Differences in phenotype between long-lived memory B cells against Plasmodium falciparum merozoite antigens and variant surface antigens., PMID:38895251
                                            Interleukin-10 induces TNF-driven apoptosis and ROS production in salivary gland cancer cells., PMID:38882335
                                            Molecular signatures in prion disease: altered death receptor pathways in a mouse model., PMID:38802941
                                            Peripheral CX3CR1+ T cells combined with PD-1 blockade therapy potentiates the anti-tumor efficacy for lung cancer., PMID:38798746
                                            Scattered Crypt Intestinal Epithelial Cell Apoptosis Induces Necrotizing Enterocolitis Via Intricate Mechanisms., PMID:38788898
                                            Molecular Hydrogen as a Promising Therapy Could Be Linked With Increased Resting Treg Cells or Decreased Fas+ T Cell Subsets in a IgG4-PF-ILD Patient: A Case Report., PMID:38688598
                                            Early B cell transcriptomic markers of measles-specific humoral immunity following a 3rd dose of MMR vaccine., PMID:38633249
                                            Advancements in γδT cell engineering: paving the way for enhanced cancer immunotherapy., PMID:38576617
                                            Dysregulated FGFR3 signaling alters the immune landscape in bladder cancer and presents therapeutic possibilities in an agent-based model., PMID:38515743
                                            CD40 stimulation via CD40 ligand enhances adenovirus-mediated tumour immunogenicity including 'find-me', 'eat-me', and 'kill-me' signalling., PMID:38494863
                                            Effect of Temperature on the Development of Stages of Spermatogenesis and the Functionality of Sertoli Cells In Vitro., PMID:38396838
                                            Discoidin domain receptor 2 signaling through PIK3C2α in fibroblasts promotes lung fibrosis., PMID:38332727
                                            [Lung pathology in children with a long-term novel coronavirus infection COVID-19]., PMID:38319270
                                            Early allogeneic immune modulation after establishment of donor hematopoietic cell-induced mixed chimerism in a nonhuman primate kidney transplant model., PMID:38318170
                                            Cyclizine induces cytotoxicity and apoptosis in macrophages through the extrinsic and intrinsic apoptotic pathways., PMID:38314619
                                            Membrane-bound CD95 ligand modulates CD19-mediated B cell receptor signaling and EBV activation., PMID:38299675
                                            Immune Control in Repeated Babesia microti Infection in a Patient With B-Cell Deficiency., PMID:38213635
                                            Impaired FADD/BID signaling mediates cross-resistance to immunotherapy in Multiple Myeloma., PMID:38129580
                                            NGAL Mediates Anaplastic Thyroid Carcinoma Cells Survival Through FAS/CD95 Inhibition., PMID:38091978
                                            EGF-Receptor against Amphiregulin (AREG) Influences Costimulatory Molecules on Monocytes and T Cells and Modulates T-Cell Responses., PMID:38046264
                                            The murine meninges acquire lymphoid tissue properties and harbour autoreactive B cells during chronic Trypanosoma brucei infection., PMID:37983289